Noninvasive diagnosis of hepatocellular carcinoma on gadoxetic acid-enhanced MRI: can hypointensity on the hepatobiliary phase be used as an alternative to washout?

2015 ◽  
Vol 25 (10) ◽  
pp. 2859-2868 ◽  
Author(s):  
Ijin Joo ◽  
Jeong Min Lee ◽  
Dong Ho Lee ◽  
Ju Hyeon Jeon ◽  
Joon Koo Han ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Gadoxetic Acid ◽  
Noninvasive Diagnosis ◽  
Hepatobiliary Phase ◽  
Enhanced Mri

scholarly journals Diagnostic Per-Patient Accuracy of an Abbreviated Hepatobiliary Phase Gadoxetic Acid–Enhanced MRI for Hepatocellular Carcinoma Surveillance

2015 ◽  
Vol 204 (3) ◽  
pp. 527-535 ◽  
Author(s):  
Robert M. Marks ◽  
Andrew Ryan ◽  
Elhamy R. Heba ◽  
An Tang ◽  
Tanya J. Wolfson ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Gadoxetic Acid ◽  
Hepatobiliary Phase ◽  
Enhanced Mri ◽  
Hepatocellular Carcinoma Surveillance

Hepatobiliary phase images of gadoxetic acid-enhanced MRI may improve accuracy of predicting the size of hepatocellular carcinoma at pathology

2021 ◽  
pp. 028418512110141
Author(s):  
San-Yuan Dong ◽  
Yu-Tao Yang ◽  
Wen-Tao Wang ◽  
Shuo Zhu ◽  
Wei Sun ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Correlation Coefficient ◽  
Tumor Size ◽  
Pearson Correlation ◽  
Gadoxetic Acid ◽  
Arterial Phase ◽  
Hepatobiliary Phase ◽  
Enhanced Mri ◽  
Phase Images ◽  
Mri Sequences

Background Gadoxetic acid-enhanced magnetic resonance imaging (MRI) has been widely used in clinical practice. However, scientific evidence is lacking for recommending a particular sequence for measuring tumor size. Purpose To retrospectively compare the size of hepatocellular carcinoma (HCC) measured on different gadoxetic acid-enhanced MRI sequences using pathology as a reference. Material and Methods A total of 217 patients with single HCC who underwent gadoxetic acid-enhanced MRI before surgery were included. The size of the HCC was measured by two abdominal radiologists independently on the following sequences: T1-weighted; T2-weighted; b-500 diffusion-weighted imaging (DWI); and arterial, portal venous, transitional, and hepatobiliary phases. Tumor size measured on MRI was compared with pathological size by using Pearson correlation coefficient, independent-sample t test, and Bland–Altman plot. Agreement between two readers was evaluated with intraclass correlation coefficient (ICC). Results Correlation between the MR images and pathology was high for both readers (0.899–0.955). Absolute error between MRI and pathologic assessment was lowest on hepatobiliary phase images for both readers (reader 1, 2.8±4.2 mm; reader 2, 3.2±3.4 mm) and highest on arterial phase images for reader 1 (4.9±4.4 mm) and DWI phase images for reader 2 (5.1±4.9 mm). Absolute errors were significantly different for hepatobiliary phase compared with other sequences for both readers (reader 1, P≤0.012; reader 2, P≤0.037). Inter-reader agreements for all sequence measurements were strong (0.971–0.997). Conclusion The performance of gadoxetic acid-enhanced MRI sequences varied with HCC size, and the hepatobiliary phase may be optimal among these sequences.

Added value of smooth hypointense rim in the hepatobiliary phase of gadoxetic acid-enhanced MRI in identifying tumour capsule and diagnosing hepatocellular carcinoma

2016 ◽  
Vol 27 (6) ◽  
pp. 2610-2618 ◽  
Author(s):  
Chansik An ◽  
Hyungjin Rhee ◽  
Kyunghwa Han ◽  
Jin-Young Choi ◽  
Young-Nyun Park ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Gadoxetic Acid ◽  
Added Value ◽  
Hepatobiliary Phase ◽  
Enhanced Mri

Gadoxetic acid-enhanced MRI for hepatocellular carcinoma and hypointense nodule observed in the hepatobiliary phase

2013 ◽  
Author(s):  
Elsa Iannicelli ◽  
Marco Di Pietropaolo ◽  
Massimo Marignani ◽  
Chiara Briani ◽  
Giulia Francesca Federici ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Gadoxetic Acid ◽  
Hepatobiliary Phase ◽  
Enhanced Mri

Intra-individual comparison of hepatocellular carcinoma imaging features on contrast-enhanced computed tomography, gadopentetate dimeglumine-enhanced MRI, and gadoxetic acid-enhanced MRI

2017 ◽  
Vol 59 (6) ◽  
pp. 639-648 ◽  
Author(s):  
Yo Na Kim ◽  
Ji Soo Song ◽  
Woo Sung Moon ◽  
Hong Pil Hwang ◽  
Young Kon Kim
Keyword(s):  
Computed Tomography ◽  
Hepatocellular Carcinoma ◽  
Contrast Ratio ◽  
Gadopentetate Dimeglumine ◽  
Gadoxetic Acid ◽  
Arterial Phase ◽  
Hepatobiliary Phase ◽  
Imaging Features ◽  
Enhanced Mri ◽  
Individual Comparison

Background Gadoxetic acid is being widely used for detection and characterization of hepatic nodules. However, there are no data regarding intra-individual comparison of imaging features of hepatocellular carcinoma (HCC) on dynamic computed tomography (CT), gadopentetate dimeglumine-enhanced magnetic resonance imaging (Gd-DTPA-MRI), and gadoxetic acid-enhanced MRI (Gd-EOB-MRI). Purpose To evaluate typical imaging features of HCC and capsule appearance with dynamic CT, Gd-DTPA-MRI, and Gd-EOB-MRI. Material and Methods We retrospectively reviewed 56 HCCs in 49 patients. Lesion attenuation/signal intensity was graded using a five-point scale based on dynamic phase and hepatobiliary phase (HBP) imaging. Subjective washout and capsule appearance were evaluated on portal venous phase (PVP) or delayed/transitional phase (DP/TP) imaging. The tumor-to-liver contrast ratio (TLCR) was calculated. Results Gd-DTPA-MRI and Gd-EOB-MRI was graded higher than CT on arterial phase ( P < 0.001). Gd-EOB-MRI was graded lower than Gd-DTPA-MRI on PVP and DP/TP ( P < 0.05). The detection rate of subjective washout and capsule appearance did not differ among the three imaging studies on either PVP or DP/TP. TLCR of Gd-EOB-MRI was lower than CT on PVP ( P = 0.004) and was lower than Gd-DTPA-MRI on DP/TP ( P = 0.001). Conclusion Arterial phase hyperenhancement and washout appearance of HCC were well demonstrated in Gd-EOB-MRI. The detection of capsule appearance using Gd-EOB-MRI was not inferior to Gd-DTPA-MRI or CT.

Feasibility of semiautomated MR volumetry using gadoxetic acid-enhanced MRI at hepatobiliary phase for living liver donors

2013 ◽  
Vol 72 (3) ◽  
pp. 640-645 ◽  
Author(s):  
Jeongjin Lee ◽  
Kyoung Won Kim ◽  
So Yeon Kim ◽  
Bohyoung Kim ◽  
So Jung Lee ◽  
...  
Keyword(s):  
Gadoxetic Acid ◽  
Hepatobiliary Phase ◽  
Enhanced Mri ◽  
Living Liver Donors ◽  
Mr Volumetry ◽  
Liver Donors
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