Muscle imbalance as a cause of scoliosis: a study in a fetal lamb abdominal wall defect model

2021 ◽  
Author(s):  
Kohei Kawaguchi ◽  
Juma Obayashi ◽  
Junki Koike ◽  
Kunihide Tanaka ◽  
Yasuji Seki ◽  
...  
Keyword(s):  
Abdominal Wall ◽  
Abdominal Wall Defect ◽  
Defect Model ◽  
Wall Defect ◽  
Muscle Imbalance ◽  
Fetal Lamb

scholarly journals Nitro-Oleic Acid (NO2-OA) Release Enhances Regional Angiogenesis in a Rat Abdominal Wall Defect Model

2018 ◽  
Vol 24 (11-12) ◽  
pp. 889-904 ◽  
Author(s):  
Antonio D'Amore ◽  
Marco Fazzari ◽  
Hong-Bin Jiang ◽  
Samuel K. Luketich ◽  
Michael E. Luketich ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Abdominal Wall ◽  
Abdominal Wall Defect ◽  
Defect Model ◽  
Wall Defect

Thein vivoevaluation of tissue-based biomaterials in a rat full-thickness abdominal wall defect model

2013 ◽  
Vol 102 (4) ◽  
pp. 709-720 ◽  
Author(s):  
Nicholas Bryan ◽  
Helen Ahswin ◽  
Neil Smart ◽  
Yves Bayon ◽  
Stephen Wohlert ◽  
...  
Keyword(s):  
Abdominal Wall ◽  
Abdominal Wall Defect ◽  
Full Thickness ◽  
Defect Model ◽  
Wall Defect

scholarly journals Effects of Three Different Types of Anti-adhesive Agents in a Rat Abdominal Wall Defect Model

2009 ◽  
Vol 77 (1) ◽  
pp. 7 ◽  
Author(s):  
Hyung Jun Song ◽  
Jong Won Kim ◽  
Jun Seok Park ◽  
Yong Seok Kim ◽  
Yoo Shin Choi ◽  
...  
Keyword(s):  
Abdominal Wall ◽  
Abdominal Wall Defect ◽  
Defect Model ◽  
Wall Defect ◽  
Different Types

scholarly journals An Immunopathological Evaluation of the Porcine Cholecyst Matrix as a Muscle Repair Graft in a Male Rat Abdominal Wall Defect Model

2018 ◽  
Vol 46 (2) ◽  
pp. 169-183 ◽  
Author(s):  
Dhanush Krishna Balakrishnan-nair ◽  
Narayanan Divakaran Nair ◽  
Syam Kunnekkattu Venugopal ◽  
Vijayan Narayana Das ◽  
Sisilamma George ◽  
...  
Keyword(s):  
Abdominal Wall ◽  
Abdominal Wall Defect ◽  
Host Tissue ◽  
Tissue Response ◽  
Male Rat ◽  
M2 Macrophages ◽  
Muscle Repair ◽  
Defect Model ◽  
Tissue Scaffold ◽  
Wall Defect

With the increasing use of animal-based biomaterials for regenerative medical applications, the need for their safety assessment is paramount. A porcine cholecyst-derived scaffold (CDS), intended as a muscle repair graft, prepared by a nondetergent/enzymatic method was engrafted in a rat abdominal wall defect model. Host tissue–scaffold interface samples were collected 2, 8, and 16 weeks postimplantation and evaluated by histopathology, immunohistochemistry, and electron microscopy. The nature of the tissue reaction was compared with those induced by a jejunum-derived scaffold (JDS) prepared by the same method and a commercial-grade small intestinal submucosa (CSIS) scaffold. A study of the immunopathological response in major lymphoid tissues and immunophenotyping for M1 and M2 macrophages was performed at the host tissue–scaffold interface. Further, “irritancy scores” for CDS and JDS were determined using CSIS as the reference material. Both CDS and JDS appeared to be potential biomaterials for muscle grafts, but the former stimulated a skeletal muscle tissue remodeling response predominated by M2 macrophages. The data support the notion that biomaterials with similar biocompatibility, based on local tissue response on implantation, may cause differential immunogenicity. Additionally, CDS compared to JDS and CSIS was found to be less immunotoxic.

Exploring the match between the degradation of the ECM-based composites and tissue remodeling in full-thickness abdominal wall defect model

2021 ◽  
Author(s):  
Guangxiu Cao ◽  
Wei He ◽  
Yubo Fan ◽  
Xiaoming Li
Keyword(s):  
Extracellular Matrix ◽  
Small Intestine ◽  
Abdominal Wall ◽  
Abdominal Wall Defect ◽  
Full Thickness ◽  
Small Intestine Submucosa ◽  
Defect Model ◽  
Wall Defect ◽  
Clinical Challenge ◽  
A Current

The repair of abdominal wall defect is a current clinical challenge. Naturally derived extracellular matrix (ECM) such as small intestine submucosa (SIS) has received great attention in abdominal wall defect...

Histopathologic host response to polypropylene-based surgical mesh materials in a rat abdominal wall defect model

2011 ◽  
Vol 100B (3) ◽  
pp. 709-717 ◽  
Author(s):  
Alexander Huber ◽  
Alan V. Boruch ◽  
Alejandro Nieponice ◽  
Hongbin Jiang ◽  
Christopher Medberry ◽  
...  
Keyword(s):  
Abdominal Wall ◽  
Host Response ◽  
Surgical Mesh ◽  
Abdominal Wall Defect ◽  
Defect Model ◽  
Wall Defect
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