Prevalence of colorectal cancer in acute uncomplicated diverticulitis and the role of the interval colonoscopy

2018 ◽  
Vol 33 (7) ◽  
pp. 991-994 ◽  
Author(s):  
Nicholas Yock Teck Soh ◽  
Daryl Kai Ann Chia ◽  
Nan Zun Teo ◽  
Calvin Jian Ming Ong ◽  
Ramesh Wijaya
Keyword(s):  
Colorectal Cancer ◽  
Uncomplicated Diverticulitis ◽  
Acute Uncomplicated Diverticulitis

scholarly journals Correction to: Prevalence of colorectal cancer in acute uncomplicated diverticulitis and the role of the interval colonoscopy

2018 ◽  
Vol 33 (8) ◽  
pp. 1145-1145
Author(s):  
Nicholas Yock Teck Soh ◽  
Daryl Kai Ann Chia ◽  
Nan Zun Teo ◽  
Calvin Jian Ming Ong ◽  
Ramesh Wijaya
Keyword(s):  
Colorectal Cancer ◽  
Uncomplicated Diverticulitis ◽  
Acute Uncomplicated Diverticulitis

scholarly journals 321 Role of Antibiotics in Acute uncomplicated diverticulitis, A Systematic Review and Meta-Analysis

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
A A Tahir ◽  
K M Ali ◽  
A U Khan ◽  
S Kamal ◽  
A Hussain ◽  
...  
Keyword(s):  
Systematic Review ◽  
Statistical Analysis ◽  
Treatment Failure ◽  
Hospital Stay ◽  
Meta Analysis ◽  
Dietary Advice ◽  
Duration Of Hospital Stay ◽  
Uncomplicated Diverticulitis ◽  
Acute Uncomplicated Diverticulitis

Abstract Introduction Diverticular disease is a common health problem with a wide clinical spectrum. About 75% of the patients would have uncomplicated diverticulitis. Cornerstones of treatment are antibiotics, analgesia, and dietary advice. Recent evidence has shown that its treatment is controversial, questioning the use of antibiotics. Aim is to assess the role of antibiotics in the treatment of acute uncomplicated diverticulitis. Method This is a systematic review and Meta-analysis. Literature review of the available studies was conducted using search engines like Pubmed, Medline, Embase, Google Scholar, and Cochrane databases. Statistical analysis was conducted using RevMan5.4. Results Out of 1754 records 1324 were duplicates, 430 studies were screened. 395 were further excluded.35 full text articles were assessed and in the final review 10 studies were included. PRISMA guidelines were used. Pooled OR for recurrence = 0.92 (95% CI = 0.74 to 1.13). Pooled OR for Hospital stay= -0.66 (95% CI= -1.12 to -0.21). Pooled OR for complications = 1.06 (95% CI = 0.69 to 1.64). Pooled OR for treatment failure= 1.24 (95% CI = 0.90-1.69). Conclusions We conclude that from the available evidence antibiotics have no role in reducing recurrence, complications, treatment failure, and duration of hospital stay in acute uncomplicated diverticulitis.

The role of antibiotics in acute uncomplicated diverticulitis: A systematic review and meta-analysis

2018 ◽  
Vol 216 (3) ◽  
pp. 604-609 ◽  
Author(s):  
Valentin Mocanu ◽  
Jerry T. Dang ◽  
Noah Switzer ◽  
Iran Tavakoli ◽  
Chunhong Tian ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Uncomplicated Diverticulitis ◽  
Acute Uncomplicated Diverticulitis

scholarly journals A163 THE ROLE OF ANTIBIOTICS IN ACUTE UNCOMPLICATED DIVERTICULITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS

2018 ◽  
Vol 1 (suppl_2) ◽  
pp. 244-245
Author(s):  
V Mocanu ◽  
J Dang ◽  
N Switzer ◽  
I Tavakoli ◽  
C Tian ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Uncomplicated Diverticulitis ◽  
Acute Uncomplicated Diverticulitis

Tumour Characteristics of Patients with Colorectal Cancer after Acute Uncomplicated Diverticulitis

2018 ◽  
Vol 36 (5) ◽  
pp. 362-368 ◽  
Author(s):  
Winesh Ramphal ◽  
Jennifer M.J. Schreinemakers ◽  
Tom C.J. Seerden ◽  
Paul D. Gobardhan
Keyword(s):  
Colorectal Cancer ◽  
Observational Study ◽  
Primary Endpoint ◽  
Poor Prognosis ◽  
Acute Diverticulitis ◽  
Uncomplicated Diverticulitis ◽  
Tumour Characteristics ◽  
Epidemiological Characteristics ◽  
Acute Uncomplicated Diverticulitis

Background: The association between diverticulitis and colorectal cancer (CRC) remains unclear, though both share epidemiological characteristics. The aim of this study was to investigate whether there is higher risk for CRC after an episode of uncomplicated diverticulitis. Furthermore, in cases of CRC, we sought to determine specific tumour characteristics. Methods: This retrospective observational study includes patients with acute diverticulitis (Hinchey 0 and 1) who were conservatively treated with or without antibiotics between 2008 and 2013. Patients with endoscopic follow-up were included for analysis. Tumour characteristics of patients diagnosed with CRC during colonoscopic follow-up according to patients’ presentation of alarm symptoms were considered to be the primary endpoint. Results: A total of 977 patients were conservatively treated for an episode of acute diverticulitis, 645 of whom underwent colonoscopy during follow-up. Ten patients were diagnosed with CRC, nine of whom exhibited alarm symptoms. One patient was diagnosed with stage I disease, 4 had stage II, and 5 had stage III disease. Conclusions: This study strongly suggests that even though CRC is rare after uncomplicated diverticulitis, in cases of alarm symptoms, a colonoscopy is indicated. In cases where CRC is diagnosed, it is often advanced with a higher TNM stage and poor prognosis.

T04.02.4 THE EFFICACY OF A MIX OF THREE PROBIOTIC STRAINS IN REDUCING ABDOMINAL PAIN AND INFLAMMATORY BIOMARKERS IN ACUTE UNCOMPLICATED DIVERTICULITIS

2020 ◽  
Vol 52 ◽  
pp. S129
Author(s):  
C. Petruzziello ◽  
M. Marannino ◽  
A. Migneco ◽  
M. Brigida ◽  
A. Saviano ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Inflammatory Biomarkers ◽  
Uncomplicated Diverticulitis ◽  
Probiotic Strains ◽  
Acute Uncomplicated Diverticulitis

The Contemporary Role of Resection and Ablation in Colorectal Cancer Liver Metastases

2020 ◽  
Vol 04 (03) ◽  
pp. 291-302
Author(s):  
Mariam F. Eskander ◽  
Christopher T. Aquina ◽  
Aslam Ejaz ◽  
Timothy M. Pawlik
Keyword(s):  
Colorectal Cancer ◽  
Portal Vein ◽  
Surgical Oncology ◽  
Portal Vein Ligation ◽  
Safe Alternative ◽  
Colorectal Cancer Liver Metastases ◽  
Liver Remnant ◽  
New Era ◽  
Ablation Therapy

AbstractAdvances in the field of surgical oncology have turned metastatic colorectal cancer of the liver from a lethal disease to a chronic disease and have ushered in a new era of multimodal therapy for this challenging illness. A better understanding of tumor behavior and more effective systemic therapy have led to the increased use of neoadjuvant therapy. Surgical resection remains the gold standard for treatment but without the size, distribution, and margin restrictions of the past. Lesions are considered resectable if they can safely be removed with tumor-free margins and a sufficient liver remnant. Minimally invasive liver resections are a safe alternative to open surgery and may offer some advantages. Techniques such as portal vein embolization, association of liver partition with portal vein ligation for staged hepatectomy, and radioembolization can be used to grow the liver remnant and allow for resection. If resection is not possible, nonresectional ablation therapy, including radiofrequency and microwave ablation, can be performed alone or in conjunction with resection. This article presents the most up-to-date literature on resection and ablation, with a discussion of current controversies and future directions.

The Critical Role of the miR-21-MEG2 Axis in Colorectal Cancer

2020 ◽  
Vol 30 (6) ◽  
pp. 509-518
Author(s):  
Zengtao Bao ◽  
Shanting Gao ◽  
Baoming Zhang ◽  
Wenchao Shi ◽  
Aimin Li ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Critical Role

THE ROLE OF RADIATION METHODS IN DIAGNOSIS AND STAGING OF COLORECTAL CANCER

2018 ◽  
pp. 93-102
Author(s):  
V. A. Solodkiy ◽  
N. V. Nudnov ◽  
V. D. Chhikvadze ◽  
U. S. Stanojevich ◽  
N. I. Sergeev ◽  
...  
Keyword(s):  
Colorectal Cancer
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