Visual assessment of dopaminergic degeneration pattern in 123I-FP-CIT SPECT differentiates patients with atypical parkinsonian syndromes and idiopathic Parkinson's disease

2011 ◽  
Vol 259 (2) ◽  
pp. 251-260 ◽  
Author(s):  
Deniz Kahraman ◽  
Carsten Eggers ◽  
Harald Schicha ◽  
Lars Timmermann ◽  
Matthias Schmidt
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Visual Assessment ◽  
Idiopathic Parkinson’S Disease ◽  
Parkinsonian Syndromes ◽  
Idiopathic Parkinson's Disease ◽  
Dopaminergic Degeneration

Brain metabolic correlates of dopaminergic degeneration in de novo idiopathic Parkinson’s disease

2009 ◽  
Vol 37 (3) ◽  
pp. 537-544 ◽  
Author(s):  
Valentina Berti ◽  
Cristina Polito ◽  
Silvia Ramat ◽  
Eleonora Vanzi ◽  
Maria Teresa De Cristofaro ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
De Novo ◽  
Idiopathic Parkinson’S Disease ◽  
Idiopathic Parkinson's Disease ◽  
Dopaminergic Degeneration

scholarly journals Environment, Genetics and Idiopathic Parkinson's Disease

1991 ◽  
Vol 18 (1) ◽  
pp. 70-76 ◽  
Author(s):  
Judes Poirier ◽  
Sandra Kogan ◽  
Serge Gauthier
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Current Knowledge ◽  
Idiopathic Parkinson’S Disease ◽  
Parkinsonian Syndromes ◽  
Idiopathic Parkinson's Disease ◽  
Radical Generation ◽  
Review Current ◽  
Aging Factor

ABSTRACT:Since Idiopathic Parkinson's disease (IPD) was first described more than 170 years ago, there have been major advances in the understanding of the etiology of the disease as well as in its treatment. This article will review current knowledge concerning the role of the environment, genetic hypotheses and the aging factor in the etiology of IPD and proposes a complex interaction involving all these factors. Hypotheses regarding mitochondrial inhibition and free radical generation in IPD are discussed in relation to the mechanism of action of neurotoxins known to produce parkinsonian syndromes.

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