Breast sarcoma showing myofibroblastic differentiation

2003 ◽  
Vol 443 (2) ◽  
pp. 222-224 ◽  
Author(s):  
Ksenija Lucin ◽  
Elvira Mustac ◽  
Nives Jonjic
Keyword(s):  
Breast Sarcoma ◽  
Myofibroblastic Differentiation

Radiation-induced breast sarcoma

2002 ◽  
Vol 184 (4) ◽  
pp. 356-358 ◽  
Author(s):  
D.Kay Blanchard ◽  
Carol Reynolds ◽  
Clive S Grant ◽  
David R Farley ◽  
John H Donohue
Keyword(s):  
Breast Sarcoma ◽  
Radiation Induced

Nasal Chondromesenchymal Hamartoma in Children

2001 ◽  
Vol 125 (3) ◽  
pp. 400-403 ◽  
Author(s):  
Chuen Hsueh ◽  
Swei Hsueh ◽  
Frank Gonzalez-Crussi ◽  
Ta-jen Lee ◽  
Jen-liang Su
Keyword(s):  
Immunohistochemical Study ◽  
Correct Diagnosis ◽  
S100 Protein ◽  
Soft Tissue Tumors ◽  
Biological Behavior ◽  
Ultrastructural Examination ◽  
Spindle Cells ◽  
Nasal Chondromesenchymal Hamartoma ◽  
Myofibroblastic Differentiation ◽  
Malignant Soft Tissue

Abstract Hamartoma in the nasal cavity of children is especially rare. Most documented cases occurred in infants, with characteristic histologic features of a mixture of various mesenchymal tissues. McDermott et al designated it nasal chondromesenchymal hamartoma in 1998, and it has since been considered a distinct clinicopathological entity. We report 2 such examples in a full-term male newborn and a 9-month-old boy, respectively. Histologically, both cases were characterized by a mixture of various mesenchymal elements, including spindle cells, collagen fibers, and irregular islands of osseous and chondroid tissue. Immunohistochemical study showed positivity to vimentin and S100 protein. Ultrastructural examination of case 1 demonstrated fibroblastic and myofibroblastic differentiation in tumor cells. There were 11 cases of nasal chondromesenchymal hamartoma in children published to date. The tumor has a benign biological behavior, and complete resection is the treatment of choice. It is apt to be misdiagnosed because of overlapping histologic features shared with a number of benign and malignant soft tissue tumors. Awareness of this entity is essential for correct diagnosis and adequate therapy.

scholarly journals Primary breast sarcoma: case report

2004 ◽  
Vol 81 (7) ◽  
Author(s):  
S Hassan ◽  
G Adari
Keyword(s):  
Case Report ◽  
Breast Sarcoma

Breast Sarcoma

1987 ◽  
Vol 11 (11) ◽  
pp. 905-906 ◽  
Author(s):  
Janez Lamovec
Keyword(s):  
Breast Sarcoma

scholarly journals BILATERAL BREAST SARCOMA IN WOMEN WITH MACROMASTIA

2017 ◽  
Vol 4 ◽  
pp. 49-54
Author(s):  
Igor Galaychuk ◽  
Larysa Nitefor ◽  
Irina Perepyolkina
Keyword(s):  
Ultrasound Examination ◽  
Radical Surgery ◽  
Fibrous Histiocytoma ◽  
Disease Recurrence ◽  
Postoperative Treatment ◽  
Unknown Etiology ◽  
First Year ◽  
Histological Subtypes ◽  
Breast Sarcoma ◽  
Breast Malignancies

Bilateral breast sarcomas are rare malignancies of unknown etiology. Most common histological subtypes of breast sarcoma are angiosarcoma, fibrosarcoma and malignant fibrous histiocytoma. Phyllodes tumors have a predisposition to transform into sarcoma. The present clinical case describes bilateral breast fibrosarcomas in a 39 years-old female with macromastia. This peculiarity gave possibilities to do wide local excision of both tumors within 3.0 cmresection margins and preserve both breasts. Histological and immunohistochemical (ERG, CK-AE1/AE3) examination confirmed fibrosarcomas in both breast (in right – stage IIB, in left – stage IIA). Patient carried on postoperative treatment with radiation therapy (36.1 Gy for both breasts) and four cycles of adjuvant chemotherapy (doxorubicin, cisplatin, cyclophosphamide). For the first year patient had clinical and ultrasound examination every three months, then every 6 months. CT scan of chest and abdomen was every year. In seven post-op years there was no evidence of disease recurrence. Thus, macromastia gives an exceptional chance to carry out organ-sparing radical surgery in women with advanced breast malignancies.

scholarly journals Myofibroblastic Differentiation of Human Skeletal Muscle‐Derived Progenitors Is Inhibited by Pirfenidone

2015 ◽  
Vol 29 (S1) ◽  
Author(s):  
Yasaman Alinejad ◽  
Jennifer Downey ◽  
Genevieve Drouin ◽  
Meggie Morand ◽  
Alex Daviau ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Human Skeletal Muscle ◽  
Myofibroblastic Differentiation
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