Congenital unilateral facial nerve palsy as an unusual presentation of BOR syndrome

2012 ◽  
Vol 172 (2) ◽  
pp. 273-275 ◽  
Author(s):  
Augustina Jankauskienė ◽  
Karolis Azukaitis
Keyword(s):  
Facial Nerve ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Unusual Presentation ◽  
Bor Syndrome

scholarly journals Facial nerve palsy as an unusual presentation of orbital apex syndrome

2021 ◽  
Vol 17 (2) ◽  
pp. 176-179
Author(s):  
Rafiqahmed Abdulkarim Vasiwala ◽  
◽  
Wong Zhen Yu ◽  
Tee Chen Giap ◽  
Ashiya Rafiq ◽  
...  
Keyword(s):  
Facial Nerve ◽  
Nerve Palsy ◽  
Multidisciplinary Approach ◽  
Facial Nerve Palsy ◽  
Unusual Presentation ◽  
Diabetic Patients ◽  
Fungal Sinusitis ◽  
Orbital Apex ◽  
Orbital Apex Syndrome ◽  
Diagnostic Challenge

Clinical cases of orbital apex syndrome are rare and most commonly manifested as a complication of fungal sinusitis, mainly in immunocompromised and poorly controlled diabetic patients. Rhino-orbital mucormycosis is a rare opportunistic, aggressive and fatal infection caused by mucor. The complex presentation of orbital apex syndrome not only poses a diagnostic challenge but also demands a multidisciplinary approach in patient management. Facial nerve palsy is an unusual presentation in orbital apex syndrome. We report the case of a 64-year-old diabetic patient presenting with ophthalmoplegia and visual loss associated with facial nerve palsy. Prompt ophthalmologic and otolaryngologic intervention with imaging and histologic confirmation, followed by early initiation of antifungal and antimicrobial therapy, were integral to preventing further complications, and reducing morbidity and mortality.

scholarly journals Facial Nerve Palsy: An Unusual Presentation in Patients with Rhino Cerebral Mucormycosis

2018 ◽  
Vol 71 (S3) ◽  
pp. 2110-2113 ◽  
Author(s):  
Rajashri Mane ◽  
Balasaheb Patil ◽  
Anjana Mohite ◽  
Roshni Mohanty
Keyword(s):  
Facial Nerve ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Unusual Presentation

TRANSIENT FACIAL NERVE PALSY AFTER SCALP BLOCK FOR AWAKE CRANIOTOMY: A CASE REPORT

2018 ◽  
Vol 4 (5) ◽  
pp. 369-371
Author(s):  
Rajashree U Gandhe . ◽  
Chinmaya P Bhave . ◽  
Avinash S Kakde . ◽  
Neha T Gedam .
Keyword(s):  
Case Report ◽  
Facial Nerve ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Awake Craniotomy ◽  
Scalp Block

scholarly journals Facial nerve palsy as the presenting feature of metastatic prostatic cancer in the temporal bone

2020 ◽  
Vol 6 (1) ◽  
pp. 1-5
Author(s):  
Daichi Fujii ◽  
Hikari Shimoda ◽  
Natsumi Uehara ◽  
Takeshi Fujita ◽  
Masanori Teshima ◽  
...  
Keyword(s):  
Facial Nerve ◽  
Temporal Bone ◽  
Prostatic Cancer ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Metastatic Prostatic Cancer

scholarly journals HGG-48. ROS1 INHIBITOR ENTRECTINIB USE IN RELAPSE/REFRACTORY INFANTILE GLIOBLASTOMA WITH POSITIVE ROS1 FUSION - A CASE REPORT WITH PROMISING RESPONSE

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii352-iii352
Author(s):  
Dennis Tak-Loi Ku ◽  
Matthew Ming-Kong Shing ◽  
Godfrey Chi-Fung Chan ◽  
Eric Fu ◽  
Ping-Wa Yau ◽  
...  
Keyword(s):  
Targeted Therapy ◽  
Facial Nerve ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Tumour Progression ◽  
Molecular Study ◽  
Subtotal Resection ◽  
Residual Tumour ◽  
Molecular Assay ◽  
Debulking Surgery

Abstract INTRODUCTION Infantile glioblastoma is rare with poor prognosis. Recent molecular study for infantile hemispheric high grade glioma found its association with ALK/ROS1/NTRK/MET pathway. This suggested the potential use of targeted therapy for refractory / relapse patients. CASE: A newborn presented with apnea, CT brain showed intracranial haemorrhage. MRI then showed a left parietal tumour with bleeding and mass effect. Craniotomy achieved subtotal resection. Chemotherapy VCR/CPM alternating with CDDP/VP-16 was given for one year. Patient was stable with static residual tumour during chemotherapy. However patient developed status epilepticus two weeks after off treatment. MRI showed significant tumour progression which required 2nd & 3rd debulking surgery. Molecular assay by nanostring panel showed BRAF-KIAA1549 fusion. MEK inhibitor Trametinib was tried for 3 months and stopped as disease progression. Further molecular assay by RNASeq showed presence of ROS1 fusion (ZCCHC8-ROS1) while absent of BRAF fusion. Patient underwent 4th debulking surgery as impending herniation while waiting for the targeted therapy. It was complicated with right hemiplegia and facial nerve palsy postoperatively. Finally, ROS1 inhibitor Entrectinib was started 2 weeks later. It was well tolerated without significant adverse reaction. Patient made dramatic neurological recovery including improved facial nerve palsy, able to walk unaided and self feed. MRI brain 1 and 3 months after Entrectinib showed interval reduction in residual tumour. Patient is currently progression-free for 6 months. CONCLUSION Early molecular study for infantile glioblastoma is useful to guide novel therapy. Molecular result may varies between different panels or change over time, to be interpreted with caution.

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