Prediction of type 1 diabetes in Sardinian schoolchildren using islet cell autoantibodies: 10-year follow-up of the Sardinian schoolchildren type 1 diabetes prediction study

2015 ◽  
Vol 53 (1) ◽  
pp. 73-79 ◽  
Author(s):  
Fernanda Velluzzi ◽  
◽  
Gianni Secci ◽  
Vincenzo Sepe ◽  
Catherine Klersy ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Islet Cell ◽  
Diabetes Prediction ◽  
Islet Cell Autoantibodies

scholarly journals Validity of ICA 512 As in Combination with other ISLET Cell Autoantibodies for Prediction Studies in Type 1 Diabetes

1999 ◽  
Vol 45 (3) ◽  
pp. 439-439
Author(s):  
G Krochik ◽  
C A Mazza ◽  
M Papouchado ◽  
R Stumpo ◽  
S Valdéz ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Islet Cell ◽  
Islet Cell Autoantibodies

scholarly journals Frequency of islet cell autoantibodies (IA-2 and GAD) in young Brazilian type 1 diabetes patients

1999 ◽  
Vol 32 (10) ◽  
pp. 1195-1198 ◽  
Author(s):  
V.C. Pardini ◽  
D.M. Mourão ◽  
P.D. Nascimento ◽  
M.A. Vívolo ◽  
S.R.G. Ferreira ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Islet Cell ◽  
Islet Cell Autoantibodies ◽  
Diabetes Patients

Slowly Progressing Type 1 Diabetes: Persistence of Islet Cell Autoantibodies is Related to Glibenclamide Treatment

Autoimmunity ◽  
2002 ◽  
Vol 35 (7) ◽  
pp. 469-474 ◽  
Author(s):  
Eduardo Cabrera-Rode ◽  
Pedro Perich ◽  
Oscar Diaz-Horta ◽  
Claudio Tiberti ◽  
Gisela Molina ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Islet Cell ◽  
Islet Cell Autoantibodies

scholarly journals Autoantibodies to a 38-kDa Glycosylated Islet Cell Membrane-Associated Antigen in (Pre)type 1 Diabetes: Association with IA-2 and islet cell autoantibodies

Diabetes Care ◽  
2001 ◽  
Vol 24 (7) ◽  
pp. 1181-1186 ◽  
Author(s):  
F. Winnock ◽  
M. R. Christie ◽  
M. R. Batstra ◽  
H.-J. Aanstoot ◽  
I. Weets ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Cell Membrane ◽  
Islet Cell ◽  
Islet Cell Autoantibodies

scholarly journals Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes – Type 1 Diabetes Prediction and Prevention Study (DIPP)

2018 ◽  
Author(s):  
Santosh Lamichhane ◽  
Linda Ahonen ◽  
Thomas Sparholt Dyrlund ◽  
Esko Kemppainen ◽  
Heli Siljander ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Diabetes Type ◽  
Islet Autoimmunity ◽  
Islet Autoantibody ◽  
Prevention Study ◽  
At Risk Children ◽  
Prediction And Prevention ◽  
Diabetes Prediction

AbstractType 1 diabetes (T1D) is one of the most prevalent autoimmune diseases among children in Western countries. Earlier metabolomics studies suggest that T1D is preceded by dysregulation of lipid metabolism. Here we used a lipidomics approach to analyze molecular lipids in a prospective series of 428 plasma samples from 40 children who progressed to T1D (PT1D), 40 children who developed at least a single islet autoantibody but did not progress to T1D during the follow-up (P1Ab) and 40 matched controls (CTR). Sphingomyelins were found to be persistently downregulated in PT1D when compared to the P1Ab and CTR groups. Triacylglycerols and phosphatidylcholines were mainly downregulated in PT1D as compared to P1Ab at the age of 3 months. Our study suggests that children who progressed to islet autoimmunity or overt T1D are characterized by distinct lipidomic signatures, which may be helpful in the identification of at-risk children before the initiation of autoimmunity.

Type 1 diabetes genes and islet cell autoantibodies in different cominations predict age at onset

2000 ◽  
Vol 50 ◽  
pp. 89-90
Author(s):  
Åke Lernmark ◽  
Jinko Graham ◽  
Robert Lowe ◽  
Ingrid Kockum ◽  
Mona Landin-Olsson
Keyword(s):  
Type 1 Diabetes ◽  
Islet Cell ◽  
Age At Onset ◽  
Islet Cell Autoantibodies
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