Long-term survival after a repetitive surgical approach in a patient with acinar cell carcinoma of the pancreas and recurrent liver metastases: Report of a case

Surgery Today ◽  
2010 ◽  
Vol 40 (7) ◽  
pp. 679-683 ◽  
Author(s):  
Atsushi Suzuki ◽  
Takanori Sakaguchi ◽  
Yoshifumi Morita ◽  
Kosuke Oishi ◽  
Kazuhiko Fukumoto ◽  
...  
2013 ◽  
Vol 99 (2) ◽  
pp. e61-e64 ◽  
Author(s):  
Celina Ang ◽  
Luis A Herran ◽  
Diane Reidy Lagunes ◽  
David S Klimstra ◽  
Nancy E Kemeny

2020 ◽  
Vol 27 (1) ◽  
pp. 107327482096944
Author(s):  
Wentao Zhou ◽  
Xu Han ◽  
Yuan Fang ◽  
Siyang Han ◽  
Yumeng Cai ◽  
...  

Backgrounds: Acinar cell carcinoma of the pancreas is a rare malignancy, and its features remain unclear. We aimed to analyze the clinical characteristics, treatment and prognosis of acinar cell carcinoma with our institutional case series. Methods: Patients diagnosed with acinar cell carcinoma in our hospital between 2005 and 2019 were reviewed. Investigations on clinicopathological features, treatment details and long-term survival were performed. Results: A total of 45 pathologically confirmed acinar cell carcinomas were identified. The median age at diagnosis was 58 years with a male-to-female ratio of 3.1:1. There were 24 (53.3%) localized, 5 (11.1%) locally advanced and 16 (35.6%) metastatic cases, with a pancreatic head-to-body/tail ratio of 1:1.4 for all the primary lesions. In the localized group, there were 10 pancreatoduodenectomy, 12 distal pancreatectomy, 1 total pancreatectomy, and 1 distal pancreatectomy combined with proximal gastrectomy. Among the locally advanced and metastatic cases, 13 patients received chemotherapy, 1 received concurrent radiochemotherapy, 1 underwent synchronous resection of primary tumor and liver metastasis, 1 underwent palliative operation, 1 underwent exploratory laparotomy, and 4 required no treatment. The median overall survival of this series was 18.9 months with a 5-year survival rate of 19.6%. Moreover, the resected acinar cell carcinoma patients were associated with prolonged survival compared with the unresected cases (36.6 vs. 8.5 months, P < 0.001). Conclusions: Surgical resection could improve the long-term survival of acinar cell carcinoma patients, which might also improve the prognosis of selected metastatic cases. Large-scale studies are needed to further clarify the biological behavior and clinical features, and to seek the optimal treatments.


2020 ◽  
Vol 8 (7) ◽  
pp. 1241-1250 ◽  
Author(s):  
Mariacristina Di Marco ◽  
Riccardo Carloni ◽  
Stefania De Lorenzo ◽  
Elisa Grassi ◽  
Andrea Palloni ◽  
...  

Medicine ◽  
2015 ◽  
Vol 94 (1) ◽  
pp. e378 ◽  
Author(s):  
Tatsuaki Sumiyoshi ◽  
Yasuo Shima ◽  
Takehiro Okabayashi ◽  
Akihito Kozuki ◽  
Jun Iwata ◽  
...  

Surgery Today ◽  
1999 ◽  
Vol 29 (3) ◽  
pp. 233-237 ◽  
Author(s):  
Naofumi Eriguchi ◽  
Shigeaki Aoyagi ◽  
Masao Hara ◽  
Shuichi Fukuda ◽  
Eiji Tanaka ◽  
...  

Surgery Today ◽  
1999 ◽  
Vol 29 (3) ◽  
pp. 233-237 ◽  
Author(s):  
Naofumi Eriguchi ◽  
Shigeaki Aoyagi ◽  
Masao Hara ◽  
Shuichi Fukuda ◽  
Eiji Tanaka ◽  
...  

Pancreatology ◽  
2016 ◽  
Vol 16 (4) ◽  
pp. S175
Author(s):  
Naoki Yoshida ◽  
Atsushi Kanno ◽  
Atsushi Masamune ◽  
Seiji Hongo ◽  
Eriko Nakano ◽  
...  

2008 ◽  
Vol 69 (9) ◽  
pp. 2331-2336 ◽  
Author(s):  
Yuji OSHIMA ◽  
Naohide ISAKA ◽  
Toshiaki TAKEUCHI ◽  
Seiji ARITA ◽  
Hajime TANAKA ◽  
...  

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S821
Author(s):  
R.C. Miksch ◽  
T.S. Schiergens ◽  
M.N. Thomas ◽  
M. Ilmer ◽  
J. Hidding ◽  
...  

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