Indirect Complexometric Determination of Mercury(II) Using Potassium Bromide as Selective Masking Agent

2002 ◽  
Vol 140 (1-2) ◽  
pp. 63-67 ◽  
Author(s):  
Naracham Veedu Sreekumar ◽  
Ronald Aquin Nazareth ◽  
Badiadka Narayana ◽  
Prashant Hegde ◽  
Busnur Rachotappa Manjunatha
Keyword(s):  
Potassium Bromide ◽  
Complexometric Determination

Development and Validation of an Eco-Friendly and Low-Cost Method for the Quantification of Cefepime Hydrochloride in Powder for Injectable Solution Using Infrared (IR) Spectroscopy

2020 ◽  
Vol 16 (4) ◽  
pp. 456-464
Author(s):  
Danilo F. Rodrigues ◽  
Hérida R.N. Salgado
Keyword(s):  
Ir Spectroscopy ◽  
Low Cost ◽  
Pharmaceutical Preparations ◽  
Potassium Bromide ◽  
Pharmaceutical Products ◽  
Injectable Formulation ◽  
Ich Guidelines ◽  
Lactam Ring ◽  
Development And Validation

Background: A simple, eco-friendly and low-cost Infrared (IR) method was developed and validated for the analysis of Cefepime Hydrochloride (CEF) in injectable formulation. Different from some other methods, which employ organic solvents in the analyses, this technique does not use these types of solvents, removing large impacts on the environment and risks to operators. Objective: This study aimed at developing and validating a green analytical method using IR spectroscopy for the determination of CEF in pharmaceutical preparations. Methods: The method was validated according to ICH guidelines and the quantification of CEF was performed in the spectral region absorbed at 1815-1745 cm-1 (stretching of the carbonyl group of β- lactam ring). Results: The validated method showed to be linear (r = 0.9999) in the range of 0.2 to 0.6 mg/pellet of potassium bromide, as well as for the parameters of selectivity, precision, accuracy, robustness and Limits of Detection (LOD) and Quantification (LOQ), being able to quantify the CEF in pharmaceutical preparations. The CEF content obtained by the IR method was 103.86%. Conclusion: Thus, the method developed may be an alternative in the quality control of CEF sample in lyophilized powder for injectable solution, as it presented important characteristics in the determination of the pharmaceutical products, with low analysis time and a decrease in the generation of toxic wastes to the environment.

Complexometric determination of aluminum in vanadium-containing slag

Refractories ◽  
1975 ◽  
Vol 16 (3-4) ◽  
pp. 245-247
Author(s):  
G. G. Lopachak ◽  
L. F. Gudz
Keyword(s):  
Complexometric Determination

Determination of Ethisterone by the Potassium Bromide Disk Technique

1963 ◽  
Vol 46 (4) ◽  
pp. 646-649
Author(s):  
Alma L Hayden
Keyword(s):  
Potassium Bromide ◽  
Commercial Sources

Abstract Results of determining ethisterone by the KBr disk technique are presented. Two mixtures and tablets from 2 commercial sources were analyzed by the Associate Referee and 4 collaborators. In general, the average recoveries agreed, within 4.5%, with the amounts of ethisterone which were added or declared. In most cases, the recoveries from replicate determinations agreed within 3.8%. The method is recommended for adoption as official, first action.

Infrared Determination of Barium, Strontium, and Calcium Carbonates, Singly and Together, by the Pellet Technique

1971 ◽  
Vol 25 (2) ◽  
pp. 226-228 ◽  
Author(s):  
David E. Chasan ◽  
George Norwitz
Keyword(s):  
Potassium Bromide ◽  
Calcium Carbonates ◽  
Barium Strontium

Methods are proposed for the ir determination of barium, strontium, and calcium carbonates, singly or together, by the pellet technique. The sample is weighed into a tarred mortar using a semimicrobalance and is mixed with 300 mg of potassium bromide. The pellet is then formed and the peak heights are determined at the appropriate peak. The measurements for barium, strontium, and calcium carbonates are made at 693 cm−1, 704 cm−1 (or 698 cm−1), or 712 cm−1, respectively. The method for the mixed carbonates can be used down to a concentration of 5% of the minor ingredient. Sulfates and nitrates do not interfere with any of the procedures.

scholarly journals Selective Complexometric Determination of Palladium by Using L-Cystine as Releasing Agent

2015 ◽  
Vol 27 (3) ◽  
pp. 882-884
Author(s):  
K.G. Chandrashekhara ◽  
N. Gopalakrishna Bhat ◽  
P. Nagaraj
Keyword(s):  
Complexometric Determination

Complexometric Determination of Sulfate

1958 ◽  
Vol 30 (6) ◽  
pp. 1032-1035 ◽  
Author(s):  
K. F. Sporek
Keyword(s):  
Complexometric Determination
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