A one-pot multicomponent reaction for synthesis of 1-amidoalkyl-2-naphthols catalyzed by PEG-based dicationic acidic ionic liquids under solvent-free conditions

2011 ◽  
Vol 142 (9) ◽  
pp. 923-930 ◽  
Author(s):  
Jun Luo ◽  
Qiang Zhang
Keyword(s):  
Ionic Liquids ◽  
Multicomponent Reaction ◽  
Solvent Free ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Acidic Ionic Liquids

One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones Catalyzed by Acidic Ionic Liquids Under Solvent-Free Conditions

2009 ◽  
Vol 39 (19) ◽  
pp. 3436-3443 ◽  
Author(s):  
Jianzhou Gui ◽  
Dan Liu ◽  
Chan Wang ◽  
Feng Lu ◽  
Jingzhao Lian ◽  
...  
Keyword(s):  
Ionic Liquids ◽  
Solvent Free ◽  
One Pot ◽  
One Pot Synthesis ◽  
Solvent Free Conditions ◽  
Acidic Ionic Liquids

scholarly journals Long-chain Brønsted Acidic Ionic Liquids Catalyzed one-pot three-component Biginelli Reaction under Solvent-Free Conditions

2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Leqin He
Keyword(s):  
Ionic Liquids ◽  
Biginelli Reaction ◽  
Aromatic Aldehydes ◽  
Catalytic Performance ◽  
Solvent Free ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Acidic Ionic Liquids ◽  
Halogen Free ◽  
Long Chain

A series of halogen-free quaternary ammonium Brønsted acidic ionic liquids (ILs) were prepared and used for Biginelli reaction among aromatic aldehydes, urea or thiourea and β-dicarbonyl compounds. The influencing factors, such as the type and amount of catalyst, solvent, reaction time and reaction temperature, were investigated. The results demonstrated that the 3-(N,N-dimethylhexadecylammonium) propanesulfonic acid toluene sulfate ([DHPA][Tos]) provide the best catalytic activity, with good catalytic performance and reusability under solvent-free conditions. A possible mechanism that accounted for the [DHPA][Tos]-catalyzed reaction was proposed.

scholarly journals Assembly of fully substituted triazolochromenes via a novel multicomponent reaction or mechanochemical synthesis

2018 ◽  
Vol 14 ◽  
pp. 2689-2697 ◽  
Author(s):  
Robby Vroemans ◽  
Yenthel Verhaegen ◽  
My Tran Thi Dieu ◽  
Wim Dehaen
Keyword(s):  
Multicomponent Reaction ◽  
Mechanochemical Synthesis ◽  
Solvent Free ◽  
Viable Alternative ◽  
Dipolar Cycloaddition ◽  
One Pot ◽  
Biologically Relevant ◽  
Metal Free ◽  
Organic Azides ◽  
Solvent Free Conditions

A new metal-free one-pot three-component procedure towards fully substituted triazolochromenes has been developed, starting from commercially available materials. Salicylaldehydes and nitroalkenes were reacted under solvent-free conditions, followed by a 1,3-dipolar cycloaddition of the intermediate 3-nitro-2H-chromenes with organic azides in a one-pot two-step sequence. The triazolochromenes were formed with complete regioselectivity and new biologically relevant structures were synthesized via extension of the developed procedure and via postfunctionalization. The mechanochemical synthesis was carried out for several salicylaldehydes and gave a clear improvement in the yield of the corresponding triazolochromenes and consequently showed to be a viable alternative for solid salicylaldehydes.

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