Ionic interaction of tri-armed structure based on benzene ring: synthesis and characterization

2021 ◽  
Author(s):  
Mohammed Hadi Ali Al-Jumaili ◽  
Nihat Akkurt ◽  
Lokman Torun
Keyword(s):  
Benzene Ring ◽  
Synthesis And Characterization ◽  
Ionic Interaction ◽  
Ring Synthesis

scholarly journals Synthesis and Characterization of New Mannich Bases Derived from 7-hydroxy-4-methyl Coumarin

2016 ◽  
Vol 13 (2) ◽  
pp. 235-243
Author(s):  
Baghdad Science Journal
Keyword(s):  
Spectral Analysis ◽  
Mass Spectrum ◽  
Physical Properties ◽  
Benzene Ring ◽  
Sodium Acetate ◽  
Mannich Bases ◽  
Primary Amines ◽  
Synthesis And Characterization ◽  
Coumarin Derivatives

Coumarin is a natural substance isolated from different plants. It belonges to a group of benzobyrones which consists of a benzene ring joined to a pyrone nucleus. In the present research, a new series of coumarin derivatives were formed. Compound (1) (7-hydroxy-4-methyl Coumarin) was converted into 4-methylquinolin-2(H) derivative (2) by reaction with acetamide, and then reaction of (2) with thiosemicarbazide in ethanol leads to the synthesize of hydrazincarbothioamide derivative (3).The reaction of (3) with ethylchloroacetate in presence of sodium acetate leads to closure ring to get [(1-(5-oxo-2-thioxoimidazolidin-1-ylimino) ethyl)]quinolin-2(1H)-one (4). Mannich bases were prepared through the reaction of (4) with primary amines to form compounds (5-6). New coumarin derivatives were characterized by their physical properties and various spectral analysis like: FTIR, 1HNMR spectra and GC-Mass spectrum for some of them.

scholarly journals Six-armed Structures Based on Benzene Ring, Synthesis and Characterization Via Sonogashira Coupling

2020 ◽  
Vol 20 (3) ◽  
pp. 705
Author(s):  
Mohammed Hadi Ali Al-Jumaili ◽  
Ahmed Solaiman Hamed ◽  
Nihat Akkurt ◽  
Lokman Torun
Keyword(s):  
Differential Scanning Calorimetry ◽  
Benzene Ring ◽  
Organic Salt ◽  
Synthesis And Characterization ◽  
Spectroscopic Methods ◽  
Sonogashira Coupling ◽  
Scanning Calorimetry ◽  
Organic Salts ◽  
Crystal Property ◽  
Liquid Crystal Property

A new six-armed compounds consist of benzene ring as a central core substituted with aromatic ring and three rod-like armed of 2-chloro-4,6-bis(dodecyloxy)-1,3,5-triazine as the peripheral arms unit which obtained by sequential nucleophilic substitution of chlorine atoms in cyanuric chloride. The substitution took place at the acetylenic periphery on the central benzene ring by Sonogashira coupling. Equimolar mixtures of the six-armed compounds based on the benzene core with the complementary 4-dodecyloxybenzoic acid, which already possessed liquid crystal property, resulted in an organic salt. The organic salts and structures were investigated by differential scanning calorimetry (DSC), and confirmed by spectroscopic methods (1H-NMR, 13C-NMR and Mass spectroscopy)

scholarly journals Difluoro-Substituted bicyclo[1.1.1]pentanes as Novel Motifs for Medicinal Chemistry: Design, Synthesis and Characterization

2019 ◽  
Author(s):  
Roman Bychek ◽  
Valeriia Hutskalova ◽  
Julia Bas ◽  
Olga A. Zaporozhets ◽  
Sergei Zozulya ◽  
...  
Keyword(s):  
Drug Discovery ◽  
Benzene Ring ◽  
Medicinal Chemistry ◽  
Synthesis And Characterization ◽  
Synthetic Approach ◽  
Design Synthesis ◽  
New Generation

Herein we developed a practical synthetic approach to the previously unknown difluoro-substituted bicyclo[1.1.1]pentanes. The key step was an addition of difluorocarbene to electron-rich bicyclo[1.1.0]butanes by CF<sub>3</sub>TMS/NaI system. The obtained difluoro-bicyclo[1.1.1]pentanes are a new generation of saturated bioisosteres of the benzene ring for drug discovery projects.

A Triple Newman-Kwart Rearrangement at a Fully Substituted Benzene Ring

2009 ◽  
Vol 64 (11-12) ◽  
pp. 1633-1638 ◽  
Author(s):  
Hubert Theil ◽  
Roland Fröhlich ◽  
Thorsten Glaser
Keyword(s):  
Single Crystal ◽  
Benzene Ring ◽  
Structure Analysis ◽  
Synthesis And Characterization ◽  
X Ray ◽  
Benzene Rings

The Newman-Kwart rearrangement of O-thiocarbamates to S-thiocarbamates is a versatile method for the conversion of phenols into thiophenols. The triple rearrangement of the O-trithiocarbamate 2,4,6-triacetyl-1,3,5-tri-(dimethylthiocarbamoyloxy)benzene (2) to the S-trithiocarbamate 2,4,6- triacetyl-1,3,5-tri-(dimethylthiocarbamoylthio)benzene (3) is performed, which is unprecendented for fully substituted benzene rings. The synthesis and characterization of the O-trithiocarbamate 2 and the S-trithiocarbamate 3 including the single-crystal X-ray structure analysis of compound 3 are presented

Poly-guanidinoethylphenylethers organised around a benzene ring: Synthesis and evaluation of their antibacterial and cytotoxic properties

2014 ◽  
Vol 24 (20) ◽  
pp. 4791-4793 ◽  
Author(s):  
Hugues Massimba Dibama ◽  
Maxime Mourer ◽  
Raphaël E. Duval ◽  
Jean-Bernard Regnouf-de-Vains
Keyword(s):  
Benzene Ring ◽  
Ring Synthesis
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