Long-term retention rates of adalimumab and infliximab in non-infectious intermediate, posterior, and panuveitis

2018 ◽  
Vol 38 (1) ◽  
pp. 63-70 ◽  
Author(s):  
Claudia Fabiani ◽  
Antonio Vitale ◽  
Giacomo Emmi ◽  
Alice Bitossi ◽  
Giuseppe Lopalco ◽  
...  
Keyword(s):  
Retention Rates ◽  
Term Retention ◽  
Long Term Retention

scholarly journals Long-term retention rates of antiepileptic drugs used in acute seizures

Seizure ◽  
2018 ◽  
Vol 61 ◽  
pp. 78-82 ◽  
Author(s):  
Manuel Toledo ◽  
Elena Fonseca ◽  
Marta Olivé ◽  
Manuel Requena ◽  
Manuel Quintana ◽  
...  
Keyword(s):  
Antiepileptic Drugs ◽  
Retention Rates ◽  
Acute Seizures ◽  
Term Retention ◽  
Long Term Retention

scholarly journals Prevalence, Safety and Long-Term Retention Rates of Biologics in Hong Kong from 2001 to 2015

Drug Safety ◽  
2019 ◽  
Vol 42 (9) ◽  
pp. 1091-1102
Author(s):  
Mengqin Ge ◽  
Kenneth K. Man ◽  
Celine S. Chui ◽  
Esther W. Chan ◽  
Ian C. Wong ◽  
...  
Keyword(s):  
Hong Kong ◽  
Retention Rates ◽  
Term Retention ◽  
Long Term Retention

Long-term Retention Rates and Complications of Silicone Punctal Plugs in Dry Eye

2008 ◽  
Vol 145 (3) ◽  
pp. 586 ◽  
Author(s):  
Zeynel A. Karcioglu ◽  
J. Chris Fleming
Keyword(s):  
Dry Eye ◽  
Retention Rates ◽  
Punctal Plugs ◽  
Term Retention ◽  
Long Term Retention

scholarly journals P.005 Long-term retention on adjunctive brivaracetam in adults with focal seizures and previous carbamazepine, lamotrigine, levetiracetam, or topiramate use: Post-hoc analysis

2019 ◽  
Vol 46 (s1) ◽  
pp. S14-S15
Author(s):  
K Foris ◽  
M Martin ◽  
S Dimova ◽  
S Elmoufti ◽  
C Laloyaux ◽  
...  
Keyword(s):  
Retention Rates ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Post Hoc Analysis ◽  
Focal Seizures ◽  
Term Retention ◽  
Kaplan Meier ◽  
Long Term Retention ◽  
Post Hoc

Background: Previous post-hoc analysis of three 12-week, double-blind, placebo-controlled trials of adjunctive brivaracetam (BRV) in patients with focal seizures demonstrated similar efficacy over placebo regardless of previous carbamazepine (CBZ), lamotrigine (LTG), levetiracetam (LEV), or topiramate (TPM) failure. This analysis explored long-term retention of adjunctive BRV in patients with previous CBZ/LTG/LEV/TPM. Methods: Post-hoc analysis of double-blind, placebo-controlled trial (N01358 [NCT01261325]) and open-label extension (N01379 [NCT01339559]; cut-off 15-March-2017) of adjunctive BRV in patients (≥16 years) with focal seizures. Outcomes were assessed in patients randomized to BRV (100 or 200 mg/day) who had previous CBZ/LTG/LEV/TPM (stopped ≥90 days before BRV initiation). Results: 503 patients were analyzed. Baseline characteristics were generally similar in subgroups with previous CBZ/LTG/LEV/TPM (n=209/162/256/182). Overall, Kaplan-Meier-estimated BRV retention at 1-, 3-, and 5-years was 71.0%, 50.9%, and 32.4%. Across previous antiepileptic drug (AED) subgroups, Kaplan-Meier-estimated BRV retention (1-year: 64.8%–73.2%; 3-year: 41.9%–49.9%; 5-year: 31.5%–35.7%), BRV discontinuations (58.4%–63.0%), and most common reasons for discontinuation (lack of efficacy: 23.0%–25.3%; adverse event: 16.7%–22.2%) were generally similar. Conclusions: Post-hoc analysis demonstrated similar long-term retention rates and discontinuation reasons with adjunctive BRV in adults previously treated with CBZ/LTG/LEV/TPM. Adjunctive BRV provides long-term effectiveness in patients who failed common AED treatments, including LEV.UCB Pharma-sponsored

Long-term retention rates for antiepileptic drugs: A review of long-term extension studies and comparison with brivaracetam

2017 ◽  
Vol 138 ◽  
pp. 53-61 ◽  
Author(s):  
Manuel Toledo ◽  
Rebecca Beale ◽  
Jennifer S. Evans ◽  
Sara Steeves ◽  
Sami Elmoufti ◽  
...  
Keyword(s):  
Antiepileptic Drugs ◽  
Retention Rates ◽  
Term Retention ◽  
Long Term Retention

scholarly journals The Effects of Three Spacing Methods on Students’ Mid- to Long-term Retention of Lexis

2016 ◽  
Vol 40 (2) ◽  
pp. 3
Author(s):  
James Bury
Keyword(s):  
Student Performance ◽  
Retention Rates ◽  
Japanese University ◽  
Positive Effects ◽  
Spaced Retrieval ◽  
Term Retention ◽  
Spacing Interval ◽  
Learning Conditions ◽  
Long Term Retention

This article investigates the effect that six different lexical spacing interval schedules had on Japanese university students’ retention of lexis on a translation test completed in the first and last lessons of a 15-lecture course. Two schedules used an expanded spaced retrieval (ESR) technique, two employed a uniform spaced retrieval (USR) technique, and two were based on massed retrieval (MR) methods. It was found that the ESR and USR schedules had greater positive effects on student performance than MR. It is also posited that the challenging learning conditions created by expanding the intervals between the initial encoding of a lexical item and subsequent retrieval attempts can positively affect students’ retention rates and overall learning experiences. Consequently, it is suggested that teachers and curriculum developers implement ESR and USR techniques more when planning and adapting materials. 本論は、日本の大学生が全15回の講義の初回と最終回に行う訳の試験での語彙定着力に、6つの異なる語彙分散間隔スケジュールがどのような効果を与えるかを調査したものである。2つで間隔伸張検索（ESR: expanded spaced retrieval）法を使用し、別の2つで均一間隔検索(USR: uniform spaced retrieval) 法、残りの2つは集中検索 (MR: massed retrieval) 法を用いた。結果としてESRとUSRは、MRよりも学生の成績により良い影響を与えた。また、語彙の最初の発信と次の検索の間隔を延ばすという厳しい学習条件が、学生の語彙の定着率と総体的な学習経験に良い影響を与えると仮定される。そのため、教師やカリキュラム作成者は、教材の教授予定を作成する際、より多くのESRやUSR法を取り入れるよう推奨したい。

scholarly journals Long-Term Retention of Passive Integrated Transponder Tags Injected into the Pelvic Girdle of Adult Walleye

2020 ◽  
Vol 11 (2) ◽  
pp. 593-596
Author(s):  
Jonathan R. Meerbeek
Keyword(s):  
Pelvic Girdle ◽  
Retention Rates ◽  
Passive Integrated Transponder ◽  
Pit Tags ◽  
Natural Lakes ◽  
Term Retention ◽  
Low Probability ◽  
Long Term Retention ◽  
Pit Tagging

Abstract We assessed long-term retention of passive integrated transponder (PIT) tags injected into the subcutaneous musculature between the pelvic fins of adult Walleye Sander vitreus via collecting fish from natural lakes in northwestern Iowa during April 2015, examining fish for the presence of an existing visual implant tag (used as secondary mark), implanting PIT tags in a representative subsample of previously marked fish, and recapturing fish during subsequent annual surveys. Of the 332 Walleye (range = 444–706 mm; mean total length = 544 mm; standard deviation = 43) PIT tagged in 2015, 87 of 88 (98.9%) recaptured from 1 to 4 y after tagging retained their tag. We captured 23 Walleye more than once (≥ 2 y after tagging) and all Walleye had retained their tag on their second or third recapture. This study and others demonstrate that the pelvic girdle was an effective PIT-tagging location for long-term studies evaluating adult Walleye population dynamics. In addition, the low probability of tags being encountered in fish fillets by anglers makes this a desirable tag location for Walleye studies where Walleye are often targeted for consumption. These studies collectively demonstrate that PIT tags inserted into the pelvic girdle of a range of Walleye sizes yield retention rates suitable for advanced population modeling or stocking evaluations.

scholarly journals Sustained Long-Term Retention Rates of Abatacept in Combination with Conventional Synthetic Disease-Modifying Antirheumatic Drugs in Elderly Patients with Rheumatoid Arthritis

Medicina ◽  
2021 ◽  
Vol 57 (9) ◽  
pp. 914
Author(s):  
Shuzo Sato ◽  
Haruki Matsumoto ◽  
Jumpei Temmoku ◽  
Yuya Fujita ◽  
Naoki Matsuoka ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Concomitant Administration ◽  
Retention Rates ◽  
Disease Modifying Antirheumatic Drugs ◽  
Antirheumatic Drugs ◽  
Younger Patients ◽  
Term Retention ◽  
Long Term Retention ◽  
Disease Modifying

Background and Objectives: Treatment for elderly (aged ≥75 years) patients with rheumatoid arthritis (RA) is important because they usually have several complications and organ dysfunction and are more susceptible to drug-related adverse events. Abatacept (ABT) treatment is relatively safe in elderly RA patients; however, the real-world data of efficacy and long-term retention of ABT is sparse in such patients. This study aimed to investigate the clinical efficacy and long-term retention rates of ABT in elderly Japanese RA patients. Materials and Methods: This 10-year retrospective observational cohort study was performed in two centers in Fukushima, Japan. We reviewed the clinical features of elderly RA patients who received ABT and investigated the differences in retention rates with concomitant administration of conventional synthetic disease-modifying antirheumatic drugs (csDMARDs). Results: The clinical characteristics of younger (<75 years old, 39 cases) and elderly (≥75 years old, 20 cases) RA patients were generally similar. Although the efficacy was also similar, the concomitant administration of csDMARDs with ABT differed between the two groups. Younger patients significantly decreased methotrexate (MTX) administration than elderly patients (p < 0.01), and elderly patients significantly received tacrolimus (TAC) (p < 0.01) or salazosulfapyridine (SASP; p = 0.01) than younger patients. The overall retention and infection-free survival rates were similar between the two groups. Conclusion: Elderly RA patients showed sustained retention rates compared to younger RA patients. TAC and SASP can help to maintain sustained retention rates in elderly RA patients.

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