Computational simulation-derived hemodynamic and biomechanical properties of the pulmonary arterial tree early in the course of ventricular septal defects

2021 ◽  
Author(s):  
Melody L. Dong ◽  
Ingrid S. Lan ◽  
Weiguang Yang ◽  
Marlene Rabinovitch ◽  
Jeffrey A. Feinstein ◽  
...  
Keyword(s):  
Computational Simulation ◽  
Biomechanical Properties ◽  
Ventricular Septal Defects ◽  
Arterial Tree ◽  
Septal Defects ◽  
Pulmonary Arterial

THE NATURAL HISTORY OF PULMONARY HYPERTENSION IN CHILDREN WITH VENTRICULAR SEPTAL DEFECTS ASSESSED BY SERIAL RIGHT-HEART CATHETERIZATION

PEDIATRICS ◽  
1961 ◽  
Vol 27 (4) ◽  
pp. 621-626
Author(s):  
Robert E. Stanton ◽  
Donald C. Fyler
Keyword(s):  
Natural History ◽  
Arterial Pressure ◽  
Pulmonary Arterial Pressure ◽  
Clinical Status ◽  
Right Heart Catheterization ◽  
Heart Catheterization ◽  
Ventricular Septal Defects ◽  
Septal Defects ◽  
History Of ◽  
Pulmonary Arterial

The natural history of the pulmonary arterial pressure in 23 children with isolated ventricular septal defects has been evaluated by serial night heart catheterization. In none of the 23 patients was there a significant increase in pulmonary arterial pressure. Eight patients showed a significant decrease. The direction of shunts did not change between procedures, and the clinical status was stable. Our experience correlated well with the majority of institutions. It would appear that the natural course of pulmonary arterial pressure in ventricular septal defect is not commonly one of progressive rise.

scholarly journals Unidirectional valved patch closure of ventricular septal defects with severe pulmonary arterial hypertension: Hemodynamic outcomes

2014 ◽  
Vol 148 (6) ◽  
pp. 2570-2575 ◽  
Author(s):  
Sachin Talwar ◽  
Vikas Kumar Keshri ◽  
Shiv Kumar Choudhary ◽  
Saurabh Kumar Gupta ◽  
Sivasubramanian Ramakrishnan ◽  
...  
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Ventricular Septal Defects ◽  
Septal Defects ◽  
Patch Closure ◽  
Pulmonary Arterial ◽  
Severe Pulmonary Arterial Hypertension

Pulmonary arterial changes in patients with ventricular septal defects and severe pulmonary hypertension

1986 ◽  
Vol 7 (3) ◽  
pp. 147-154 ◽  
Author(s):  
Ruthellen Fried ◽  
George Falkovsky ◽  
Jane Newburger ◽  
A. I. Gorchakova ◽  
Marlene Rabinovitch ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Severe Pulmonary Hypertension ◽  
Ventricular Septal Defects ◽  
Septal Defects ◽  
Pulmonary Arterial

INCREASING PULMONARY VASCULAR RESISTANCE DURING INFANCY IN ASSOCIATION WITH VENTRICULAR SEPTAL DEFECT

PEDIATRICS ◽  
1966 ◽  
Vol 38 (2) ◽  
pp. 220-230 ◽  
Author(s):  
Julien I. E. Hoffman ◽  
Abraham M. Rudolph
Keyword(s):  
Ventricular Septal Defect ◽  
Vascular Disease ◽  
Pulmonary Vascular Resistance ◽  
Vascular Resistance ◽  
Septal Defect ◽  
The Other ◽  
Pulmonary Vascular Disease ◽  
Ventricular Septal Defects ◽  
Septal Defects ◽  
Pulmonary Arterial

Three children with big ventricular septal defects, large pulmonary blood flows, and pulmonary hypertension were catheterized at the ages of 3, 6, and 6 months. Pulmonary vascular resistance was low in two and slightly raised in the other. Recatheterization at the ages of 9, 16, and 26 months, respectively, showed increases of pulmonary vascular resistance in all, and the ventricular septal defects were successfully closed by open-heart operation soon thereafter. In the one child who was recatheterized only after there was clinical evidence of a raised pulmonary vascular resistance, postoperative catheterization showed a progressive rise in pulmonary vascular resistance indicating progressive pulmonary vascular disease. The other two children who were clinically well were recatheterized specifically to try and detect early pulmonary vascular changes and, in contrast, in both of these children pulmonary arterial pressures and vascular resistances have returned to normal after operation. These patients demonstrate that in those at risk of developing pulmonary vascular disease (big ventricular septal defect with high pressures and flows), pulmonary vascular resistance can rise rapidly in early life. In these patients progressive pulmonary vascular disease could be prevented if surgery to lower pulmonary arterial pressure and blood flow is done early enough. Even in patients who appear to be improving, recatheterization is necessary to demonstrate a moderate rise in pulmonary vascular resistance, since a moderate rise is not detectable by current clinical techniques.

Pulmonary arterial development in infants with large perimembranous ventricular septal defects associated with overriding of the aortic valve

1985 ◽  
Vol 7 (3) ◽  
pp. 223-230 ◽  
Author(s):  
Ernesto Janeda ◽  
Adriana Gittenberger de Groot ◽  
Arentje Oppenheimer-Dekker ◽  
Sheila G. Haworth
Keyword(s):  
Aortic Valve ◽  
Ventricular Septal Defects ◽  
Septal Defects ◽  
Pulmonary Arterial ◽  
Arterial Development

scholarly journals Hemodynamic effects of pulmonary arterial stenosis in experimental ventricular septal defects

1968 ◽  
Vol 55 (3) ◽  
pp. 340-349
Author(s):  
Allyn G. May ◽  
Erling B. Christopher sen ◽  
Stanley Middleman ◽  
James A. DeWeese ◽  
Earle B. Mahoney
Keyword(s):  
Arterial Stenosis ◽  
Hemodynamic Effects ◽  
Ventricular Septal Defects ◽  
Septal Defects ◽  
Pulmonary Arterial ◽  
Pulmonary Arterial Stenosis

scholarly journals Trans-pulmonary arterial repair of supracristal ventricular septal defects in infancy

1980 ◽  
Vol 80 (6) ◽  
pp. 948-950 ◽  
Author(s):  
J. Tharion ◽  
T.B. Cartmill ◽  
D.C. Johnson ◽  
J.M. Celermajer
Keyword(s):  
Ventricular Septal Defects ◽  
Septal Defects ◽  
Arterial Repair ◽  
Pulmonary Arterial
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