scholarly journals Ischemia reperfusion-facilitated sinusoidal endothelial cell injury in liver transplantation and the resulting impact of extravasated platelet aggregation

2015 ◽  
Vol 48 (2) ◽  
pp. 92-98 ◽  
Author(s):  
T. Miyashita ◽  
S. Nakanuma ◽  
A.K. Ahmed ◽  
I. Makino ◽  
H. Hayashi ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Endothelial Cell ◽  
Platelet Aggregation ◽  
Cell Injury ◽  
Ischemia Reperfusion ◽  
Sinusoidal Endothelial Cell ◽  
Endothelial Cell Injury

Sinusoidal endothelial cell injury by superoxide anion and iron in the Propionibacterium acnes -pretreated and lipopolysaccharide-stimulated rat liver

2001 ◽  
Vol 21 (6) ◽  
pp. 415-424 ◽  
Author(s):  
Tadashi Hasegawa ◽  
Minoru Nakano ◽  
Takashi Hashimoto ◽  
Katsuya Hiraishi ◽  
Keiji Suzuki ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Rat Liver ◽  
Superoxide Anion ◽  
Cell Injury ◽  
Propionibacterium Acnes ◽  
Sinusoidal Endothelial Cell ◽  
Endothelial Cell Injury

Endothelial Cell Injury in Cardiovascular Surgery: The Systemic Inflammatory Response11Recent discoveries in the field of vascular biology have led to an expanded understanding of the pathogenesis of many of the immediate and long-term complications of patients undergoing cardiovascular operations and interventional cardiologic procedures. In particular, the vascular endothelium has emerged as the central focus of many of the biologic events that affect the preoperative, operative, and postoperative course of nearly all heart surgery patients. A recurring theme in the study of endothelial cell biology is the crucial role that endothelial cell injury plays in the difficulties that our patients encounter. The deleterious effects of endothelial cell injury are most evident in the acute syndromes of vasospasm, coagulopathy, ischemia/reperfusion injury, and the systemic inflammatory response to cardiopulmonary bypass. In addition, chronic endothelial cell injury contributes to the development of anastomotic narrowing and the progression of atherosclerosis, both of which limit the long-term success of coronary artery bypass grafting. Because of the increasingly recognized role of the endothelium in cardiovascular function there is a tremendous amount of basic science information detailing the response of the endothelium to injury. This is the fifth in a series of seven reviews intended as an introduction to the major topics of endothelial cell biology that are of importance to the practicing cardiothoracic surgeon. In particular, the authors have focused on the role that the endothelium has on the development of vasomotor dysfunction, bleeding and thrombosis, neutrophil-endothelial cell interaction, and obstructive arteriopathy. The aim of these reviews is to provide a concise reference point for cardiothoracic surgeons as they evaluate the ever-accumulating research findings and new therapies that stem from the study of the endothelium in response to the insults encountered in cardiothoracic surgery.Edward D. Verrier, MD

1997 ◽  
Vol 63 (1) ◽  
pp. 277-284 ◽  
Author(s):  
Edward M Boyle, MD ◽  
Timothy H Pohlman, MD ◽  
Marion C Johnson, MD ◽  
Edward D Verrier, MD
Keyword(s):  
Endothelial Cell ◽  
Cell Biology ◽  
Heart Surgery ◽  
Cell Injury ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Artery Bypass ◽  
Cell Interaction ◽  
Endothelial Cell Injury

scholarly journals Sinusoidal endothelial cell repopulation following ischemia/reperfusion injury in rat liver transplantation

Hepatology ◽  
2007 ◽  
Vol 46 (5) ◽  
pp. 1464-1475 ◽  
Author(s):  
Donna Beer Stolz ◽  
Mark A. Ross ◽  
Atsushi Ikeda ◽  
Koji Tomiyama ◽  
Takashi Kaizu ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Endothelial Cell ◽  
Reperfusion Injury ◽  
Rat Liver ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Sinusoidal Endothelial Cell ◽  
Rat Liver Transplantation ◽  
Cell Repopulation

Endothelial Cell Injury in Cardiovascular Surgery: Ischemia-Reperfusion

1996 ◽  
Vol 62 (6) ◽  
pp. 1868-1875 ◽  
Author(s):  
Edward M. Boyle ◽  
Timothy H. Pohlman ◽  
Carol J. Cornejo ◽  
Edward D. Verrier
Keyword(s):  
Endothelial Cell ◽  
Cell Injury ◽  
Cardiovascular Surgery ◽  
Ischemia Reperfusion ◽  
Endothelial Cell Injury

scholarly journals Liver sinusoidal endothelial cell injury by neutrophils in rats with acute obstructive cholangitis

2002 ◽  
Vol 8 (2) ◽  
pp. 342 ◽  
Author(s):  
Jian-Ping Gong ◽  
Chuan-Xin Wu ◽  
Chang-An Liu ◽  
Sheng-Wei Li ◽  
Yu-Jun Shi ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Cell Injury ◽  
Sinusoidal Endothelial Cell ◽  
Liver Sinusoidal Endothelial Cell ◽  
Endothelial Cell Injury ◽  
Obstructive Cholangitis
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