Neuroticism and Attention Toward Sexual and Non-Sexual Images During an Oddball Task: Evidence from Event-Related Potentials

The lateral distribution of the P300 component of the event-related brain potential (ERP) was studied in five epileptic patients whose corpus callosum had been surgically sectioned and in seven neurologically intact controls. The P300 was elicited in an auditory “oddball” task using high- and low-pitched tones and in a visual oddball task in which target words were presented either to the left or right visual fields, or to both fields simultaneously. Commissurotomy altered the normal pattern of bilaterally symmetrical P300 waves over the left and right hemispheres, but in a different manner for auditory and visual stimuli. The auditory P3 to binaural tones was larger in amplitude over the right than the left hemisphere for the patients. In the visual task, the laterality of the P300 varied with the visual field of the target presentation. Left field targets elicited much larger P300 amplitudes over the right than the left hemisphere, as did bilateral targets. In contrast, right field targets triggered P300 waves of about the same amplitude over the two hemispheres. The overall amplitude of the P300 to simultaneous bilateral targets was less than the sum of the individual P300 amplitudes produced in response to the unilateral right and left field targets. These shifts in P300 laterality argue against the view that the P300 is an index of diffuse arousal or activation that is triggered in both hemispheres simultaneously irrespective of which hemisphere processes the target information. The results further demonstrate that the P300 does not depend for its production on interhemispheric comparisons of information mediated by the corpus callosum, as suggested recently by Knight et al. (1989).

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The P300 component decreases in a bimodal oddball task in individuals with depression: An event-related potentials study

Clinical Neurophysiology ◽

10.1016/j.clinph.2018.09.012 ◽

2018 ◽

Vol 129 (12) ◽

pp. 2525-2533 ◽

Cited By ~ 5

Author(s):

Cai Nan ◽

Gaohua Wang ◽

Huiling Wang ◽

Xiaoping Wang ◽

Zhongchun Liu ◽

...

Keyword(s):

Event Related Potentials ◽

P300 Component ◽

Oddball Task ◽

Related Potentials

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Identical event-related potentials to target and frequent stimuli of visual oddball task recorded by intracerebral electrodes

Clinical Neurophysiology ◽

10.1016/s1388-2457(03)00108-1 ◽

2003 ◽

Vol 114 (7) ◽

pp. 1292-1297 ◽

Cited By ~ 8

Author(s):

M. Kukleta ◽

M. Brázdil ◽

R. Roman ◽

P. Jurák

Keyword(s):

Event Related Potentials ◽

Oddball Task ◽

Related Potentials ◽

Visual Oddball

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Event-related potentials in an auditory semantic oddball task in humans

Neuroscience Letters ◽

10.1016/s0304-3940(01)02057-2 ◽

2001 ◽

Vol 310 (2-3) ◽

pp. 93-96 ◽

Cited By ~ 32

Author(s):

Boris Kotchoubey ◽

Simone Lang

Keyword(s):

Event Related Potentials ◽

Oddball Task ◽

Related Potentials

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Event-related potentials in adults with Attention-Deficit/Hyperactivity Disorder: An investigation using an inter-modal auditory/visual oddball task

International Journal of Psychophysiology ◽

10.1016/j.ijpsycho.2008.09.009 ◽

2009 ◽

Vol 71 (2) ◽

pp. 124-131 ◽

Cited By ~ 42

Author(s):

Robert J. Barry ◽

Adam R. Clarke ◽

Rory McCarthy ◽

Mark Selikowitz ◽

Christopher R. Brown ◽

...

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Attention Deficit ◽

Event Related Potentials ◽

Hyperactivity Disorder ◽

Oddball Task ◽

Related Potentials ◽

Visual Oddball

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The Effect of Transcutaneous Auricular Vagal Nerve Stimulation (taVNS) on P3 Event-Related Potentials during a Bayesian Oddball Task

Brain Sciences ◽

10.3390/brainsci10060404 ◽

2020 ◽

Vol 10 (6) ◽

pp. 404 ◽

Cited By ~ 1

Author(s):

Claire V. Warren ◽

María J. Maraver ◽

Alberto de Luca ◽

Bruno Kopp

Keyword(s):

Nerve Stimulation ◽

Event Related Potentials ◽

Vagal Nerve ◽

Event Related Potential ◽

Vagal Nerve Stimulation ◽

Healthy Individuals ◽

Non Invasive ◽

Oddball Task ◽

Related Potentials ◽

Stimulation Technique

Transcutaneous auricular Vagal Nerve Stimulation (taVNS) is a non-invasive brain stimulation technique associated with possible modulation of norepinephrinergic (NE) activity. NE is suspected to contribute to generation of the P3 event-related potential. Recent evidence has produced equivocal evidence whether taVNS influences the P3 in healthy individuals during oddball tasks. We examined the effect of taVNS on P3 amplitudes using a novel visual Bayesian oddball task, which presented 200 sequences of three stimuli. The three consecutive stimuli in each sequence are labelled Draw 1, Draw 2 and Draw 3. In total, 47 Subjects completed this visual Bayesian oddball task under randomised sham and active taVNS stimulation in parallel with an electroencephalographic (EEG) recording. We conducted exploratory analyses of the effect of taVNS on P3 amplitudes separately for Draws. We found typical oddball effects on P3 amplitudes at Draws 1 and 2, but not Draw 3. At Draw 2, the oddball effect was enhanced during active compared to sham taVNS stimulation. These data provide evidence that taVNS influences parietal P3 amplitudes under specific circumstances. Only P3 amplitudes at Draw 2 were affected, which may relate to closure of Bayesian inference after Draw 2. Our findings seemingly support previously reported links between taVNS and the NE system.

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Effects of chronic antipsychotic treatment on neurophysiological correlates of the auditory oddball task in schizophrenia: A preliminary report from a multicentre study

European Psychiatry ◽

10.1016/j.eurpsy.2017.01.2124 ◽

2017 ◽

Vol 41 (S1) ◽

pp. S192-S192

Author(s):

G. Di Lorenzo ◽

A. Mucci ◽

A. Vignapiano ◽

G. Giordano ◽

F. Ferrentino ◽

...

Keyword(s):

Brain Function ◽

Event Related Potentials ◽

Chronic Administration ◽

P300 Amplitude ◽

P300 Latency ◽

Antipsychotic Treatment ◽

Auditory Oddball ◽

Oddball Task ◽

Related Potentials ◽

Auditory Oddball Task

IntroductionThe effects of chronic antipsychotic administration on the human brain are debated. In particular, first-generation (FGAs) and second-generation antipsychotics (SGAs) seem to have different impacts on brain function and structure in subjects with schizophrenia. Few studies have investigated the effect of chronic administration of FGAs and SGAs on indices of brain function, such as event-related potentials (ERP) or neuropsychological performance.ObjectivesWithin the Italian Network for Research on Psychoses study, subjects stabilized on FGAs or SGAs were compared on P300, an ERP component, thought to reflect attention, working memory and context integration and on neurocognitive indices.MethodsERPs were recorded in 110 chronic, stabilized patients with Schizophrenia (28 used FGAs) during a standard auditory oddball task. P300 latency and amplitude were assessed at Pz channel. MATRICS Consensus Cognitive Battery (MCCB) was used for cognitive assessment.ResultsCompared with the SGAs group, patients on FGAs showed significant increased P300 latency (P = 0.003; Cohen's d = 0.67) and significant decreased P300 amplitudes (P = 0.023; Cohen's d = 0.38). The two groups did not differ on psychopathology and MCCB scores. Multiple linear regressions revealed that “FGAs vs. SGAs” (β = 0.298, P = 0.002) and MCCB neurocognitive composite T-score (β = –0.273, P = 0.004) were independent predictors of P300 latency, whereas only age (β = –0.220, P = 0.027) was an independent predictor of P300 amplitude.ConclusionsFGAs seem to affect the functional brain activity more than SGAs, particularly slowing cortical processing. Our results suggest that discrepant findings concerning P300 latency in schizophrenia might be related to the type of antipsychotic treatment used. Longitudinal studies are needed to further address this issue.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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