Highly regioselective synthesis of undecylenic acid esters of purine nucleosides catalyzed by Candida antarctica lipase B

2011 ◽  
Vol 33 (11) ◽  
pp. 2233-2240 ◽  
Author(s):  
Wen-Li Gao ◽  
Ning Li ◽  
Min-Hua Zong
Keyword(s):  
Candida Antarctica ◽  
Regioselective Synthesis ◽  
Candida Antarctica Lipase B ◽  
Undecylenic Acid ◽  
Candida Antarctica Lipase ◽  
Lipase B ◽  
Acid Esters

Engineering of Candida antarctica lipase B for hydrolysis of bulky carboxylic acid esters

2010 ◽  
Vol 150 (4) ◽  
pp. 474-480 ◽  
Author(s):  
P.B. Juhl ◽  
K. Doderer ◽  
F. Hollmann ◽  
O. Thum ◽  
J. Pleiss
Keyword(s):  
Carboxylic Acid ◽  
Candida Antarctica ◽  
Candida Antarctica Lipase B ◽  
Candida Antarctica Lipase ◽  
Lipase B ◽  
Hydrolysis Of ◽  
Acid Esters

Combinatorial enzymic synthesis for functional testing of phenolic acid esters catalysed by Candida antarctica lipase B (Novozym 435®)

2007 ◽  
Vol 40 (5) ◽  
pp. 1078-1086 ◽  
Author(s):  
David E. Stevenson ◽  
Shanthi G. Parkar ◽  
Jingli Zhang ◽  
Roger A. Stanley ◽  
Dwayne J. Jensen ◽  
...  
Keyword(s):  
Phenolic Acid ◽  
Candida Antarctica ◽  
Candida Antarctica Lipase B ◽  
Novozym 435 ◽  
Functional Testing ◽  
Candida Antarctica Lipase ◽  
Lipase B ◽  
Enzymic Synthesis ◽  
Acid Esters

Sequential resolution of ethyl 3-aminobutyrate with carboxylic acid esters by Candida antarctica lipase B

1999 ◽  
Vol 10 (13) ◽  
pp. 2573-2581 ◽  
Author(s):  
Szilvia Gedey ◽  
Arto Liljeblad ◽  
Ferenc Fülöp ◽  
Liisa T. Kanerva
Keyword(s):  
Carboxylic Acid ◽  
Candida Antarctica ◽  
Candida Antarctica Lipase B ◽  
Candida Antarctica Lipase ◽  
Lipase B ◽  
Acid Esters

Pore-expanded SBA-15 for the immobilization of a recombinant Candida antarctica lipase B: Application in esterification and hydrolysis as model reactions

2018 ◽  
Vol 129 ◽  
pp. 12-24 ◽  
Author(s):  
Nathalia Saraiva Rios ◽  
Maisa Pessoa Pinheiro ◽  
Magno Luís Bezerra Lima ◽  
Denise Maria Guimarães Freire ◽  
Ivanildo José da Silva ◽  
...  
Keyword(s):  
Candida Antarctica ◽  
Candida Antarctica Lipase B ◽  
Candida Antarctica Lipase ◽  
Lipase B ◽  
Model Reactions

Structural effects on chemo- and enantioselectivity of Candida antarctica lipase B - Resolution of β-amino esters

2002 ◽  
Vol 80 (6) ◽  
pp. 565-570 ◽  
Author(s):  
Szilvia Gedey ◽  
Arto Liljeblad ◽  
László Lázár ◽  
Ferenc Fülöp ◽  
Liisa T Kanerva
Keyword(s):  
Key Words ◽  
Candida Antarctica ◽  
Diisopropyl Ether ◽  
The Other ◽  
Candida Antarctica Lipase B ◽  
Candida Antarctica Lipase ◽  
Structural Effects ◽  
Lipase B ◽  
Amino Esters ◽  
Catalyzed Reactions

The Candida antarctica lipase B-catalyzed reactions of five β-amino esters with neat butyl butanoate and with 2,2,2-trifluoroethyl butanoate in diisopropyl ether were studied, as were the reactions of the same β-amino esters and their N-butanamides with neat butanol. The possibility for sequential resolution, where the amino and ester functions of the substrate both react with an achiral butanoate, became less likely with increasing size of the substrate from ethyl 3-aminobutanoate (1a) to pentanoate (1b) or larger. On the other hand, the alcoholyses of N-acylated β-amino esters successfully proceeded in butanol with E > 100. Gram-scale resolution of the N-butanoylated 1a was performed to demonstrate the usefulness of the method. Key words: lipase, interesterification, acylation, alcoholysis, resolution, β-amino esters.

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