Prognostic significance of androgen receptor expression in invasive breast cancer: transcriptomic and protein expression analysis

2016 ◽  
Vol 159 (2) ◽  
pp. 215-227 ◽  
Author(s):  
Mohammad A. Aleskandarany ◽  
Rezvan Abduljabbar ◽  
Ibraheem Ashankyty ◽  
Ahmed Elmouna ◽  
Dena Jerjees ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Androgen Receptor ◽  
Protein Expression ◽  
Expression Analysis ◽  
Invasive Breast Cancer ◽  
Prognostic Significance ◽  
Receptor Expression ◽  
Androgen Receptor Expression

scholarly journals Prognostic significance of androgen receptor expression in HER2-positive and triple-negative breast cancer

2018 ◽  
Vol 69 (2) ◽  
pp. 157-168 ◽  
Author(s):  
Betul Bolat Kucukzeybek ◽  
Ibrahım V. Bayoglu ◽  
Yuksel Kucukzeybek ◽  
Yasar Yıldız ◽  
Utku Oflazoglu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Androgen Receptor ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Prognostic Significance ◽  
Receptor Expression ◽  
Androgen Receptor Expression ◽  
Her2 Positive

Evaluation of the prognostic significance of androgen receptor expression in metastatic breast cancer

2006 ◽  
Vol 449 (1) ◽  
pp. 24-30 ◽  
Author(s):  
Walter Schippinger ◽  
Peter Regitnig ◽  
Nadia Dandachi ◽  
Klaus-Dieter Wernecke ◽  
Thomas Bauernhofer ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Metastatic Breast Cancer ◽  
Androgen Receptor ◽  
Prognostic Significance ◽  
Metastatic Breast ◽  
Receptor Expression ◽  
Androgen Receptor Expression

scholarly journals Expression level of androgen receptors in tumor tissue and its prognostic significance in primary operable luminal breast cancer without overexpression of Her2/neu in postmenopausal women

2019 ◽  
Vol 100 (1) ◽  
pp. 112-116 ◽  
Author(s):  
O I Kit ◽  
Yu S Shatova ◽  
V V Tokmakov ◽  
I A Novikova ◽  
E P Ul’yanova ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Androgen Receptor ◽  
Postmenopausal Women ◽  
Androgen Receptors ◽  
Prognostic Significance ◽  
Receptor Expression ◽  
Androgen Receptor Expression ◽  
Luminal Breast Cancer ◽  
Luminal A ◽  
Luminal B

Aim. To evaluate the expression level and prognostic significance of androgen in primary operable luminal breast cancer without overexpression of Her2/neu in postmenopausal women. Methods. We analyzed treatment outcomes of 60 cases of primary operable (T1-2N0M0) luminal breast cancer without overexpression of Her2/neu in postmenopausal women. The follow-up period was 5 years. All cases were divided by immunohistochemical method into luminal A (20 females) and luminal B (40 patients) subtypes. Along with the standard panel of immunohistochemical markers, expression of nuclear androgen receptors was measured in tumor tissues of all patients. Depending on the expression levels, patients with luminal A and B subtypes were divided into three groups: (1) with high, (2) moderate and (3) low or negative expression. Results. Mean levels of androgen receptor expression in the nuclei of tumor cells in patients with luminal A subtype (57.3±5.9%) were higher than those of luminal B subtype (21.4±4.04%) by 62.7% (Mann-Whitney test, р=0.0026). In patients with luminal A subtype, the maximal accumulation of androgen receptors in the nuclei of tumor cells was 2.7 times higher (р=0.0023) than in patients with luminal B subtype. All cases diagnosed with the disease progression were characterized by low or negative level of nuclear androgen receptor expression. Conclusion. Negative and low levels of androgen receptor expression in tumor tissues of postmenopausal patients with luminal primary operable breast cancer without overexpression of Her2/neu might be an independent factor associated with poor prognosis.

scholarly journals Are There Differences in Androgen Receptor Expression in Invasive Breast Cancer in African (Tanzanian) Population in Comparison With the Caucasian (Italian) Population?

2018 ◽  
Vol 9 ◽  
Author(s):  
Sara Bravaccini ◽  
Sara Ravaioli ◽  
Dino Amadori ◽  
Emanuela Scarpi ◽  
Maurizio Puccetti ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Androgen Receptor ◽  
Invasive Breast Cancer ◽  
Receptor Expression ◽  
Androgen Receptor Expression ◽  
Italian Population

scholarly journals Prognostic Significance of Androgen Receptor Expression in Triple Negative Breast Cancer: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 20 (4) ◽  
pp. e385-e396 ◽  
Author(s):  
Meng Xu ◽  
Yuan Yuan ◽  
Peijing Yan ◽  
Jiongjiong Jiang ◽  
Peilan Ma ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Systematic Review ◽  
Androgen Receptor ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Meta Analysis ◽  
Prognostic Significance ◽  
Receptor Expression ◽  
Androgen Receptor Expression

Clinicopathologic significance of androgen receptor expression in invasive breast cancer: A comprehensive analysis in large cohorts

2016 ◽  
Vol 61 ◽  
pp. S207
Author(s):  
M.A. Aleskandarany ◽  
R. Abduljabbar ◽  
S. Sonbul ◽  
C.F. Lai ◽  
S. Ali ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Androgen Receptor ◽  
Invasive Breast Cancer ◽  
Comprehensive Analysis ◽  
Receptor Expression ◽  
Androgen Receptor Expression

Androgen receptor expression in breast cancer: implications on prognosis and treatment, a brief review

2021 ◽  
pp. 111324
Author(s):  
Nusrat Jahan ◽  
Catherine Jones ◽  
Rakhshanda Layeequr Rahman
Keyword(s):  
Breast Cancer ◽  
Androgen Receptor ◽  
Receptor Expression ◽  
Androgen Receptor Expression

Clinical significance of immunohistochemical androgen receptor expression in triple negative breast cancer

The Breast ◽  
2017 ◽  
Vol 32 ◽  
pp. S45-S46
Author(s):  
E. Sakata ◽  
A. Makino ◽  
H. Miyahira ◽  
Y. Endo ◽  
H. Shibuya ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Androgen Receptor ◽  
Clinical Significance ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Receptor Expression ◽  
Androgen Receptor Expression
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