Total Parenteral Nutrition Causes Circumferential Intestinal Atrophy, Remodeling of the Intestinal Wall, and Redistribution of Eosinophils in the Rat Gastrointestinal Tract

2007 ◽  
Vol 52 (8) ◽  
pp. 1833-1839 ◽  
Author(s):  
Mikael Ekelund ◽  
Elin Kristensson ◽  
Mats Ekelund ◽  
Eva Ekblad
1977 ◽  
Vol 11 (9) ◽  
pp. 536-541 ◽  
Author(s):  
Robert Lee Hull ◽  
Dennis Cassidy

The diagnostic features of copper deficiency are discussed, and a case presentation is compared with other reports in the literature. The need for copper supplement is stressed when total parenteral nutrition (TPN) is given to patients whose gastrointestinal tract is either shortened or incapable of reabsorbing copper. Since copper is recycled through the small bowel by way of the bile, any dysfunction of this area can lead to copper deficiency during TPN if inadequate amounts of copper are added to the basic TPN solutions. It is suggested that Dr. Shils' formula be used twice weekly for prophylaxis during long-term hyperalimentation and daily as a therapeutic agent when a deficiency is diagnosed.


Nutrition ◽  
2019 ◽  
Vol 67-68 ◽  
pp. 110515 ◽  
Author(s):  
Yu-Jun Wong ◽  
Huey-Ming Lum ◽  
Stephanie Fook-Chong ◽  
Soon-Thye Lim ◽  
Ennaliza Salazar

PEDIATRICS ◽  
1982 ◽  
Vol 69 (6) ◽  
pp. 801-803
Author(s):  
Paul A. Palma ◽  
Susan B. Conley ◽  
Sharon S. Crandell ◽  
Susan E. Denson

Total parenteral nutrition has become a mainstay in the management of infants following complicated abdominal surgery. As we have become sophisticated in our understanding of micronutrient nutrition, the term total parenteral nutrition has proved more a goal to be attained than a reality. In an effort to bypass the gastrointestinal tract and nurture critically ill postoperative patients intravenously, a new setting for the manifestation of deficiency states has emerged. This is illustrated by three infants who developed zinc deficiency during postoperative parenteral alimentation despite intravenous zinc supplementation (Fig 1). The pathogenesis of this syndrome and its complications are described, possible etiologies are considered, and recommendations for prevention and therapy are suggested.


2014 ◽  
Vol 28 (5) ◽  
pp. 2073-2087 ◽  
Author(s):  
Weidong Xiao ◽  
Yongjia Feng ◽  
Jens J. Holst ◽  
Bolette Hartmann ◽  
Hua Yang ◽  
...  

2018 ◽  
Vol 24 ◽  
pp. 215-216
Author(s):  
Tariq Alrasheed ◽  
Gaurav Bhalla ◽  
Naveen Kakumanu ◽  
George Hebdon ◽  
Saleh Aldasouqi

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