scholarly journals Age-related changes in retrobulbar circulation: a literature review

2019 ◽  
Vol 40 (2) ◽  
pp. 493-501 ◽  
Author(s):  
Marta P. Wiącek ◽  
Monika Modrzejewska ◽  
Daniel Zaborski

Abstract Introduction The advances in research methods used in ophthalmology allow for an increasingly accurate examination of the eyes, as well as the morphology and function of the vessels. Colour Doppler imaging is still the first-line method for the analysis of parameters of retrobulbar circulation. Therefore, the aim of this work was to present the current state of knowledge about anatomical and functional age-related changes in retrobulbar arteries. Methods A literature search was performed mainly based on the PubMed database. Results The anatomy of retrobulbar arteries, histological background of age-related vascular changes, age-related changes in retrobulbar blood flow in the ophthalmic artery, central retinal artery, short posterior ciliary arteries, and the reference values for the age-dependent retrobulbar circulation parameters measured by colour Doppler imaging are discussed in this review. Conclusion The age of the subject should always be taken into account when interpreting the parameters of retrobulbar blood flow measured by colour Doppler imaging.

2011 ◽  
Vol 89 (8) ◽  
pp. e631-e634 ◽  
Author(s):  
Panayiota Founti ◽  
Alon Harris ◽  
Domniki Papadopoulou ◽  
Petros Emmanouilidis ◽  
Brent Siesky ◽  
...  

1995 ◽  
Vol 233 (2) ◽  
pp. 80-84 ◽  
Author(s):  
Tom H. Williamson ◽  
Gordon N. Dutton ◽  
Grant M. Baxter ◽  
Andrew Pyott ◽  
William Wykes

2011 ◽  
Vol 89 (8) ◽  
pp. e609-e630 ◽  
Author(s):  
Ingeborg Stalmans ◽  
Evelien Vandewalle ◽  
Douglas R. Anderson ◽  
Vital P. Costa ◽  
Ronald E. P. Frenkel ◽  
...  

2019 ◽  
Vol 30 (2) ◽  
pp. 235-244 ◽  
Author(s):  
Fia Vosborg ◽  
Lasse Malmqvist ◽  
Steffen Hamann

Diseases of the optic nerve head involving changes in blood flow are common. However, the pathophysiology is not always fully understood. Several non-invasive methods for measuring optic nerve head blood flow are available, but currently no gold standard has been established. Methods for measuring blood flow in optic neuropathies including colour Doppler imaging, retinal function imager, optical coherence tomography angiography and laser speckle flowgraphy are reviewed. Ultrasound colour Doppler imaging is a fast measurement technique where several different parameters, especially the blood flow velocity, can be calculated. Though used for many years in ophthalmology, its use is not standardized and it requires significant observer skills. The retinal function imager is a direct method where the haemoglobin in erythrocytes is visualized and blood flow velocities in retinal vessels are calculated from a series of photos. The technique is not suitable for direct measurement of blood flow within the optic nerve head. Laser speckle flowgraphy uses a laser light which creates a light scatter pattern in the tissue. Particles moving in the area causes changes in the speckle pattern from which a relative blood flow can be estimated. It is, however, not known whether optic nerve head microcirculation is measurable with the technique. Optical coherence tomography angiography uses multiple scans to evaluate blood flow with good reproducibility but often problems with artefacts. The technique is continuously being refined and increasingly used in research as a tool for the study of blood flow in retinopathies and optic neuropathies. Most of the conducted studies are based on small sample sizes, but some of the methods show promising results in an optic nerve head blood flow research setting. Further and larger studies are required to provide standardized and comparable measurements before one or more of the methods can be considered clinical helpful in daily practice.


Eye ◽  
1995 ◽  
Vol 9 (1) ◽  
pp. 29-33 ◽  
Author(s):  
Zahida Butt ◽  
Graham McKillop ◽  
Colm O'Brien ◽  
Paul Allan ◽  
Peter Aspinall

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