Evaluation of the effect of bimatoprost/timolol fixed combination on ocular blood flow in patients with ocular hypertension using colour Doppler imaging. Preliminary study

Diabetic retinopathy is the most common cause of vision loss among people with diabetes and a leading cause of blindness among working-age adults in India. It is a form of microangiopathy, and is the most common ocular complication seen in diabetic patients. Diabetic retinopathy progresses from non proliferative to proliferative retinopathy. The non proliferative retinopathy is the milder form and it is reversible. As the progression to proliferative retinopathy happens, the patients are symptomatic and become irreversible. Vascular changes and subsequent ocular hemodynamic changes are critical events in the pathogenesis of diabetic retinopathy. Colour doppler imaging is one of the most widely used and well-established techniques for assessing ocular blood flow velocities in the retro bulbar vessels. This is a non-invasive, painless imaging method with highly reproducibility. Estimation of orbital blood flow velocity from colour doppler imaging of the ophthalmic artery and central retinal artery is a technique offering great potential for the identification of early retinopathy in diabetic patients.

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Volumetric colour Doppler imaging: a useful tool for the determination of ocular blood flow in glaucoma patients?

Eye ◽

10.1038/sj.eye.6701935 ◽

2005 ◽

Vol 20 (6) ◽

pp. 668-673 ◽

Cited By ~ 9

Author(s):

O Zeitz ◽

S E Vilchez ◽

E T Matthiessen ◽

G Richard ◽

M Klemm

Keyword(s):

Blood Flow ◽

Ocular Blood Flow ◽

Doppler Imaging ◽

Colour Doppler ◽

Colour Doppler Imaging

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Retrobulbar ocular blood flow changes measured by colour Doppler imaging after intra-arterial chemotherapy in retinoblastoma

British Journal of Ophthalmology ◽

10.1136/bjophthalmol-2016-310056 ◽

2017 ◽

Vol 101 (10) ◽

pp. 1419-1422 ◽

Cited By ~ 4

Author(s):

Kang Xue ◽

Ailin Liu ◽

Ren Hui ◽

Jing Zhang ◽

Jiang Qian

Keyword(s):

Blood Flow ◽

Ocular Blood Flow ◽

Doppler Imaging ◽

Colour Doppler ◽

Colour Doppler Imaging ◽

Flow Changes

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Colour Doppler imaging evaluation of blood flow parameters in the ophthalmic artery in acute and chronic phases of optic neuritis in multiple sclerosis

Acta Ophthalmologica ◽

10.1111/j.1755-3768.2008.01195.x ◽

2009 ◽

Vol 87 (1) ◽

pp. 65-70 ◽

Cited By ~ 18

Author(s):

Pavel Hradílek ◽

Pavel Stourac ◽

Michal Bar ◽

Olga Zapletalová ◽

David Školoudík

Keyword(s):

Multiple Sclerosis ◽

Blood Flow ◽

Optic Neuritis ◽

Ophthalmic Artery ◽

Doppler Imaging ◽

Colour Doppler ◽

Imaging Evaluation ◽

Flow Parameters ◽

Colour Doppler Imaging

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The pulsatile ocular blood flow behaviour in open angle glaucoma patients after replacing timolol therapy with timolol and dorzolamide fixed combination: preliminary study

Acta Ophthalmologica Scandinavica ◽

10.1034/j.1600-0420.80.s236.35.x ◽

2002 ◽

Vol 80 ◽

pp. 55-56 ◽

Cited By ~ 3

Author(s):

G. Manni ◽

M. Centofanti ◽

D. Gregori ◽

F. Oddone ◽

M. Scipioni ◽

...

Keyword(s):

Blood Flow ◽

Fixed Combination ◽

Open Angle Glaucoma ◽

Ocular Blood Flow ◽

Flow Behaviour ◽

Open Angle ◽

Pulsatile Ocular Blood Flow ◽

Preliminary Study

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Age-related changes in retrobulbar circulation: a literature review

International Ophthalmology ◽

10.1007/s10792-019-01176-8 ◽

2019 ◽

Vol 40 (2) ◽

pp. 493-501 ◽

Cited By ~ 2

Author(s):

Marta P. Wiącek ◽

Monika Modrzejewska ◽

Daniel Zaborski

Keyword(s):

Blood Flow ◽

Doppler Imaging ◽

Colour Doppler ◽

Colour Doppler Imaging ◽

Age Related ◽

Pubmed Database ◽

Retrobulbar Blood Flow ◽

Circulation Parameters ◽

And Function ◽

Age Related Changes

Abstract Introduction The advances in research methods used in ophthalmology allow for an increasingly accurate examination of the eyes, as well as the morphology and function of the vessels. Colour Doppler imaging is still the first-line method for the analysis of parameters of retrobulbar circulation. Therefore, the aim of this work was to present the current state of knowledge about anatomical and functional age-related changes in retrobulbar arteries. Methods A literature search was performed mainly based on the PubMed database. Results The anatomy of retrobulbar arteries, histological background of age-related vascular changes, age-related changes in retrobulbar blood flow in the ophthalmic artery, central retinal artery, short posterior ciliary arteries, and the reference values for the age-dependent retrobulbar circulation parameters measured by colour Doppler imaging are discussed in this review. Conclusion The age of the subject should always be taken into account when interpreting the parameters of retrobulbar blood flow measured by colour Doppler imaging.

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