scholarly journals Sertoli cell-conditioned medium induces germ cell differentiation in human embryonic stem cells

2011 ◽  
Vol 28 (5) ◽  
pp. 471-480 ◽  
Author(s):  
Mieke Geens ◽  
Karen Dora Sermon ◽  
Hilde Van de Velde ◽  
Herman Tournaye
2019 ◽  
Vol 112 (3) ◽  
pp. e101-e102
Author(s):  
Aysha Trout ◽  
Philip Xie ◽  
Alessandra Parrella ◽  
Zev Rosenwaks ◽  
Gianpiero D. Palermo

2015 ◽  
Vol 21 (5) ◽  
pp. 410-423 ◽  
Author(s):  
Galbha Duggal ◽  
Björn Heindryckx ◽  
Sharat Warrier ◽  
Jasin Taelman ◽  
Margot Van der Jeught ◽  
...  

2016 ◽  
Vol 53 (4) ◽  
pp. 371-380
Author(s):  
Tarlan Eslami-Arshaghi ◽  
Saeid Vakilian ◽  
Ehsan Seyedjafari ◽  
Abdolreza Ardeshirylajimi ◽  
Masoud Soleimani ◽  
...  

PLoS ONE ◽  
2009 ◽  
Vol 4 (4) ◽  
pp. e5338 ◽  
Author(s):  
Kaori Yamauchi ◽  
Kouichi Hasegawa ◽  
Shinichiro Chuma ◽  
Norio Nakatsuji ◽  
Hirofumi Suemori

Zygote ◽  
2013 ◽  
Vol 22 (4) ◽  
pp. 513-520 ◽  
Author(s):  
I. Bahena ◽  
E. Xu ◽  
M. Betancourt ◽  
E. Casas ◽  
Y. Ducolomb ◽  
...  

SummaryIn a previous study, we have identified a set of conserved spermatogenic genes whose expression is restricted to testis and ovary and that are developmentally regulated. One of these genes, the transcription factor Mael, has been reported to play an essential role in mouse spermatogenesis. Nevertheless, the role of Mael in mouse oogenesis has not been defined. In order to analyse the role of Mael in mouse oogenesis, the expression of this gene was blocked during early oogenesis in mouse in vitro using RNAi technology. In addition, the role of Mael during differentiation of embryonic stem cells (ESC) into germ cells in vitro was analysed. Results show that downregulation of Mael by a specific short interfering RNA disrupted fetal oocyte growth and differentiation in fetal ovary explants in culture and the expression of several germ-cell markers in ESC during their differentiation. These results suggest that there is an important role for Mael in early oogenesis and during germ-cell differentiation from embryonic stem cells in mouse in vitro.


2009 ◽  
Vol 1 (2) ◽  
pp. 93-103 ◽  
Author(s):  
Zhuo Yu ◽  
Ping Ji ◽  
Jinping Cao ◽  
Shu Zhu ◽  
Yao Li ◽  
...  

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