Effect of Paullinia cupana Mart. Commercial Extract During the Aging of Middle Age Wistar Rats: Differential Effects on the Hippocampus and Striatum

2017 ◽  
Vol 42 (8) ◽  
pp. 2257-2273 ◽  
Author(s):  
Moara Rodrigues Mingori ◽  
Luana Heimfarth ◽  
Charles Francisco Ferreira ◽  
Henrique Mautone Gomes ◽  
Karla Suzana Moresco ◽  
...  
2009 ◽  
Vol 92 (2) ◽  
pp. 304-313 ◽  
Author(s):  
William J. McBride ◽  
Jonathan A. Schultz ◽  
Mark W. Kimpel ◽  
Jeanette N. McClintick ◽  
Mu Wang ◽  
...  

2006 ◽  
Vol 103 (9) ◽  
pp. 3450-3455 ◽  
Author(s):  
M. J. McKinley ◽  
D. A. Denton ◽  
C. J. Thomas ◽  
R. L. Woods ◽  
M. L. Mathai

2015 ◽  
Vol 16 (6) ◽  
pp. 775-788 ◽  
Author(s):  
Rumani Singh ◽  
Shaffi Manchanda ◽  
Taranjeet Kaur ◽  
Sushil Kumar ◽  
Dinesh Lakhanpal ◽  
...  

2020 ◽  
Vol 70 (3) ◽  
pp. 387-397 ◽  
Author(s):  
León Jesús Germán-Ponciano ◽  
Abraham Puga-Olguín ◽  
María De Jesús Rovirosa-Hernández ◽  
Mario Caba ◽  
Enrique Meza ◽  
...  

AbstractThe aim of this study was to compare the effects of acute (a single injection) and chronic (21 consecutive days) treatments with chrysin 2, 4, and 8 μmol kg−1 on anxiety-like behavior and Fos immunoreactivity in the lateral septum nucleus (LSN), a structure that is involved in the regulation of anxiety, in male Wistar rats. These effects were compared with the clinically effective anxiolytic diazepam 7 μmol kg−1. The results showed that acute, but not chronic treatment, with 4 μmol kg−1 chrysin exerted anxiolytic- and anti- depressant-like effects with these effects being similar to that of diazepam. Also, none of the above-mentioned treatments did alter Fos immunoreactivity in the LSN, but a tendency towards the reduction of this variable was detected with chrysin 4 μmol kg−1 and diazepam 7 μmol kg−1. Altogether, results suggest that chrysin exerts anxiolytic-like effects, however, it can produce pharmacological tolerance after repeated use, similar to benzodiazepines.


2018 ◽  
Vol 106 ◽  
pp. 105-111 ◽  
Author(s):  
Priscila Vázquez-León ◽  
Carolina Campos-Rodríguez ◽  
Carlos Gonzalez-Pliego ◽  
Abraham Miranda-Páez

Sign in / Sign up

Export Citation Format

Share Document