Middle age onset short-term intermittent fasting dietary restriction prevents brain function impairments in male Wistar rats

2015 ◽  
Vol 16 (6) ◽  
pp. 775-788 ◽  
Author(s):  
Rumani Singh ◽  
Shaffi Manchanda ◽  
Taranjeet Kaur ◽  
Sushil Kumar ◽  
Dinesh Lakhanpal ◽  
...  
Keyword(s):  
Dietary Restriction ◽  
Brain Function ◽  
Wistar Rats ◽  
Middle Age ◽  
Intermittent Fasting ◽  
Short Term ◽  
Male Wistar Rats

Short term inhalation toxicity of a liquid aerosol of CdS/Cd(OH)2 core shell quantum dots in male Wistar rats

2012 ◽  
Vol 208 (2) ◽  
pp. 115-124 ◽  
Author(s):  
L. Ma-Hock ◽  
S. Brill ◽  
W. Wohlleben ◽  
P.M.A. Farias ◽  
C.R. Chaves ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Wistar Rats ◽  
Core Shell ◽  
Inhalation Toxicity ◽  
Short Term ◽  
Male Wistar Rats

No effect of acute tryptophan depletion on phosphodiesterase inhibition-related improvements of short-term object memory in male Wistar rats

2013 ◽  
Vol 128 (2) ◽  
pp. 107-113 ◽  
Author(s):  
E. L. van Donkelaar ◽  
J. Prickaerts ◽  
S. Akkerman ◽  
K. Rutten ◽  
H. W. M. Steinbusch ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Acute Tryptophan Depletion ◽  
Tryptophan Depletion ◽  
Phosphodiesterase Inhibition ◽  
Short Term ◽  
Object Memory ◽  
Male Wistar Rats

Reproductive toxicity of lapachol in adult male Wistar rats submitted to short-term treatment

2007 ◽  
Vol 21 (7) ◽  
pp. 658-662 ◽  
Author(s):  
Rita de Cássia da Silveira e Sá ◽  
Martha de Oliveira Guerra
Keyword(s):  
Adult Male ◽  
Wistar Rats ◽  
Reproductive Toxicity ◽  
Term Treatment ◽  
Short Term ◽  
Short Term Treatment ◽  
Male Wistar Rats

scholarly journals Late-onset intermittent fasting dietary restriction as a potential intervention to retard age-associated brain function impairments in male rats

AGE ◽  
2011 ◽  
Vol 34 (4) ◽  
pp. 917-933 ◽  
Author(s):  
Rumani Singh ◽  
Dinesh Lakhanpal ◽  
Sushil Kumar ◽  
Sandeep Sharma ◽  
Hardeep Kataria ◽  
...  
Keyword(s):  
Dietary Restriction ◽  
Brain Function ◽  
Late Onset ◽  
Male Rats ◽  
Intermittent Fasting ◽  
Potential Intervention

scholarly journals Cytokine and microRNA levels during different periods of paradoxical sleep deprivation and sleep recovery in rats

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e5567 ◽  
Author(s):  
Malinalli Brianza-Padilla ◽  
Fausto Sánchez-Muñoz ◽  
Gonzalo Vázquez-Palacios ◽  
Fengyang Huang ◽  
Julio César Almanza-Pérez ◽  
...  
Keyword(s):  
Sleep Deprivation ◽  
Wistar Rats ◽  
Inflammatory Responses ◽  
Paradoxical Sleep ◽  
Serum Levels ◽  
Paradoxical Sleep Deprivation ◽  
Short Term ◽  
Threefold Increase ◽  
Male Wistar Rats

Background Sleep has a fundamental role in the regulation of homeostasis. The aim of this study was to assess the effect of different periods of paradoxical sleep deprivation (PSD) and recovery on serum levels of cytokines and miRNAs related to inflammatory responses. Methods Male Wistar rats were submitted to a PSD of 24, 96, or 192 h, or of 192 h followed by 20 days of recovery (192 h PSD+R). The concentrations of corticosterone, cytokines (IL-6, TNF, IL-10, Adiponectin) and miRNAs (miR-146a, miR-155, miR-223, miR-16, miR-126, miR-21) in serum were evaluated. Results At PSD 24 h a significant increase of IL-6 and decrease of IL-10 were observed. At PSD 96h adiponectin increased. At 192 h of PSD IL-6 increased significantly again, accompanied by a threefold increase of IL-10 and an increase of serum corticosterone. After 20 days of recovery (192 h PSD+R) corticosterone, IL-6 and TNF levels increased significantly, while IL-10 decreased also significantly. Regarding the miRNAs at 24 h of PSD serum miR-146a, miR-155, miR-223, and miR-16 levels all increased. At 96 h of PSD miR-223 decreased. At 192 h of PSD decreases in miR-16 and miR-126 were observed. After recovery serum miR-21 increased and miR-16 decreased. Conclusion PSD induces a dynamic response likely reflecting the induced cellular stress and manifested as variating hormonal and inflammatory responses. Sleep deprivation disturbed corticosterone, cytokine and miRNA levels in serum related to the duration of sleep deprivation, as short-term PSD produced effects similar to those of an acute inflammatory response and long-term PSD induced long-lasting disturbances of biological mediators.

scholarly journals Correction to: Sterigmatocystin moderately induces oxidative stress in male Wistar rats after short-term oral treatment

2020 ◽  
Author(s):  
Dubravka Rašić ◽  
Daniela Jakšić ◽  
Andrea Hulina Tomašković ◽  
Domagoj Kifer ◽  
Nevenka Kopjar ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Wistar Rats ◽  
Oral Treatment ◽  
Short Term ◽  
Male Wistar Rats

EFFECT OF AEROBIC EXERCISE ON SHORT-AND LONG-TERM MEMORY IN ADULT MALE WISTAR RATS

2020 ◽  
pp. 15-18
Author(s):  
SOPHIE YOLANDA ◽  
GUSTI CANDRA PAMUNGKAS ◽  
TRINOVITA ANDRAINI ◽  
DEWI IRAWATI SOERIA SANTOSO ◽  
SUHARTI BINTI SIDIK ◽  
...  
Keyword(s):  
Aerobic Exercise ◽  
Wistar Rats ◽  
Short Term Memory ◽  
Memory Function ◽  
Long Term Memory ◽  
Short Term ◽  
Term Memory ◽  
Significant Difference ◽  
Male Wistar Rats

Objective: Memory is an essential function of cognition in humans, but an age- and disease-related deterioration of this function is common. The currently known treatments have high failure rates, and thus, the slowing down of memory degeneration at an early age is the preferred preventive approach. Exercise, specifically aerobic exercise, has been proven to enhance memory via various pathways, such as neurogenesis, angiogenesis, and growth factor expression. The aim of this study is to assess the effect of aerobic exercise on short-term and long-term memory function in rats. Methods: Twenty-four male Wistar rats aged 7 mo were randomly distributed into four groups: Control, short-term memory (C-S); Control, long-term memory (C-L); Aerobic, short-term memory (A-S); and Aerobic, long-term memory (A-L). The aerobic groups received exercise treatment for 30 min each five times per week, at a treadmill speed of 20 m/min. The treatment duration was 8 w. Short-term memory was assessed using the forced alteration Y-maze test, and long-term memory was assessed using the object location task. Results: The findings showed that rats placed under the aerobic exercise regimen had significantly better long-term memory function at the end of 8 w (p = 0.006), while no significant difference was observed in short-term memory function between the aerobic exercise group and the control group. Conclusion: The present study shows that aerobic exercise is beneficial in improving long-term memory function in rats.

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