Three-component condensation of 4-aminoisothiazole derivatives with aldehydes and Meldrum’s acid. Synthesis of 6,7-dihydro-4H-isothiazolo[4,5-b]pyridin-5-ones

Russian Chemical Bulletin ◽

10.1007/s11172-009-0211-3 ◽

2009 ◽

Vol 58 (7) ◽

pp. 1538-1541 ◽

Author(s):

B. V. Lichitsky ◽

A. N. Komogortsev ◽

R. M. Belyi ◽

A. A. Dudinov ◽

M. M. Krayushkin

Keyword(s):

Acid Synthesis ◽

Meldrum's Acid ◽

Meldrum’S Acid

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Some Unusual Reactions of Meldrum's Acid. Synthesis of Cinnamic Acids, Coumarins and 2-Benzyl-1-Indanone

Journal of Chemical Research ◽

10.3184/030823406776331151 ◽

2006 ◽

Vol 2006 (1) ◽

pp. 12-14 ◽

Author(s):

P. P. Mahulikar ◽

R. B. Mane

Keyword(s):

Acid Synthesis ◽

Meldrum's Acid ◽

Cinnamic Acids ◽

Meldrum’S Acid

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Dual Inhibition of AChE and BChE with the C-5 Substituted Derivative of Meldrum’s Acid: Synthesis, Structure Elucidation, and Molecular Docking Studies

Crystals ◽

10.3390/cryst7070211 ◽

2017 ◽

Vol 7 (7) ◽

pp. 211 ◽

Author(s):

Haroon Mehfooz ◽

Aamer Saeed ◽

Anamika Sharma ◽

Fernando Albericio ◽

Fayaz Larik ◽

...

Keyword(s):

Molecular Docking ◽

Structure Elucidation ◽

Acid Synthesis ◽

Docking Studies ◽

Meldrum's Acid ◽

Meldrum’S Acid ◽

Molecular Docking Studies ◽

Dual Inhibition

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C,O-Dialkylation of Meldrum's Acid: Synthesis and Reactivity of 1,3,7,7-Tetramethyl-4H,10H-6,8,9-trioxa-2-thiabenz[f]azulen-5-one

The Journal of Organic Chemistry ◽

10.1021/jo034708i ◽

2003 ◽

Vol 68 (19) ◽

pp. 7455-7459 ◽

Author(s):

Chad A. Snyder ◽

John P. Selegue ◽

Eniolami Dosunmu ◽

Nathan C. Tice ◽

Sean Parkin

Keyword(s):

Acid Synthesis ◽

Meldrum's Acid ◽

Meldrum’S Acid

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5-Arylidene derivatives of Meldrum’s acid: Synthesis, structural characterization using single crystal and powder crystal X-ray diffraction, and electronic properties

Journal of Molecular Structure ◽

10.1016/j.molstruc.2015.03.002 ◽

2015 ◽

Vol 1092 ◽

pp. 51-62 ◽

Author(s):

Tanusri Dey ◽

Soumen Ghosh ◽

Somnath Ghosh ◽

Alok Kumar Mukherjee

Keyword(s):

Single Crystal ◽

Electronic Properties ◽

Structural Characterization ◽

Acid Synthesis ◽

Meldrum's Acid ◽

X Ray Diffraction ◽

Meldrum’S Acid ◽

X Ray ◽

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Three-component condensation of 5-aminopyrazole derivatives with isatins and Meldrum’s acid. Synthesis of 1,7-dihydrospiro[pyrazolo[3,4-b]-pyridine-4,3′-indole]-2′,6(1′H,5H)-diones

Russian Chemical Bulletin ◽

10.1007/s11172-009-0202-4 ◽

2009 ◽

Vol 58 (7) ◽

pp. 1504-1508 ◽

Author(s):

B. V. Lichitsky ◽

A. N. Komogortsev ◽

A. A. Dudinov ◽

M. M. Krayushkin

Keyword(s):

Acid Synthesis ◽

Meldrum's Acid ◽

Meldrum’S Acid

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Three-Component Condensation of 4-Imino-1-Phenylimidazolidin-2-One with Aldehydes and Meldrum's Acid: Synthesis of Imidazo[4,5-b]Pyridine-2,5(4H,6H)-Diones and 5-Substituted 1-Phenylhydantoins

Chemistry of Heterocyclic Compounds ◽

10.1007/s10593-019-02548-9 ◽

2019 ◽

Vol 55 (9) ◽

pp. 851-855 ◽

Author(s):

Constantine S. Krylov ◽

Andrey N. Komogortsev ◽

Boris V. Lichitsky ◽

Artem N. Fakhrutdinov ◽

Arkady А. Dudinov ◽

...

Keyword(s):

Acid Synthesis ◽

Meldrum's Acid ◽

Meldrum’S Acid ◽

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Three-component condensation of 5-aminoimidazole derivatives with aldehydes and Meldrum’s acid. Synthesis of 3,4,6,7-tetrahydroimidazo[4,5-b]pyridin-5-ones

Russian Chemical Bulletin ◽

10.1007/s11172-012-0211-6 ◽

2012 ◽

Vol 61 (8) ◽

pp. 1591-1595 ◽

Author(s):

B. V. Lichitsky ◽

A. N. Komogortsev ◽

A. A. Dudinov ◽

M. M. Krayushkin

Keyword(s):

Acid Synthesis ◽

Meldrum's Acid ◽

Meldrum’S Acid

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Electrochemical Oxidation of Catechols in the Presence of Phenyl-Meldrum's Acid. Synthesis and Kinetic Evaluation

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.58.23 ◽

2010 ◽

Vol 58 (1) ◽

pp. 23-26 ◽

Author(s):

Davood Nematollahi ◽

Maryam Bamzadeh ◽

Hasan Shayani-Jam

Keyword(s):

Electrochemical Oxidation ◽

Acid Synthesis ◽

Meldrum's Acid ◽

Meldrum’S Acid ◽

Kinetic Evaluation

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Three-component condensation of 3-aminothiophene derivatives with isatines and Meldrum’s acid. Synthesis of 2,5′-dioxo-3′-phenyl-5′,6′-dihydro-4′H-spiro[indoline-3,7′-thieno[3,2-b]pyridine]-2′-carboxylic acids

Russian Chemical Bulletin ◽

10.1007/s11172-013-0136-8 ◽

2013 ◽

Vol 62 (4) ◽

pp. 1026-1031 ◽

Author(s):

B. V. Lichitsky ◽

R. M. Belyi ◽

A. N. Komogortsev ◽

A. A. Dudinov ◽

M. M. Krayushkin

Keyword(s):

Carboxylic Acids ◽

Acid Synthesis ◽

Meldrum's Acid ◽

Meldrum’S Acid

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One-Pot Three-Component Condensation of β-Naphthol with Arylaldehydes and Meldrum's Acid: Synthesis of 1-Aryl-1,2-Dihydro-Benzo[f]Chromen-3-Ones

Journal of Chemical Research ◽

10.3184/174751917x14902201357374 ◽

2017 ◽

Vol 41 (4) ◽

pp. 250-252 ◽

Author(s):

Hossein Mehrabi ◽

Faezeh Najafian-Ashrafi ◽

Reza Ranjbar-Karimi

Keyword(s):

Spectroscopic Data ◽

Acid Synthesis ◽

Meldrum's Acid ◽

Meldrum’S Acid ◽

One Pot ◽

Simple Method ◽

Three Component Reaction

An efficient and simple method for the synthesis of 1-aryl-1,2-dihydro-benzo[f]chromen-3-ones via a one-pot three-component reaction of β-naphthol, arylaldehydes and Meldrum's acid with Et3N as a base in CH3CN under reflux is reported. All the products were obtained in good to excellent yields and their structures were established from their spectroscopic data.

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