One-Pot Three-Component Condensation of β-Naphthol with Arylaldehydes and Meldrum's Acid: Synthesis of 1-Aryl-1,2-Dihydro-Benzo[f]Chromen-3-Ones

2017 ◽  
Vol 41 (4) ◽  
pp. 250-252 ◽  
Author(s):  
Hossein Mehrabi ◽  
Faezeh Najafian-Ashrafi ◽  
Reza Ranjbar-Karimi

An efficient and simple method for the synthesis of 1-aryl-1,2-dihydro-benzo[f]chromen-3-ones via a one-pot three-component reaction of β-naphthol, arylaldehydes and Meldrum's acid with Et3N as a base in CH3CN under reflux is reported. All the products were obtained in good to excellent yields and their structures were established from their spectroscopic data.

2018 ◽  
Vol 42 (6) ◽  
pp. 326-328 ◽  
Author(s):  
Hossein Mehrabi ◽  
Tayebeh Yarahmadi ◽  
Farzaneh Alizadeh Bami

A one-pot method for the preparation of new 4-aryl-2-thioxo-3,4-dihydropyrimidines via a three-component reaction of Meldrum's acid with arylaldehydes and acetylthiourea in the presence of p-toluenesulfonic acid as catalyst in CH3CN under reflux is reported.


2020 ◽  
Vol 23 (23) ◽  
pp. 2626-2634
Author(s):  
Saiedeh Kamalifar ◽  
Hamzeh Kiyani

: An efficient and facial one-pot synthesis of 4-aryl-3,4-dihydrobenzo[g]quinoline- 2,5,10(1H)-triones was developed for the first time. The process proceeded via the three-component cyclocondensation of 2-amino-1,4-naphthoquinone with Meldrum’s acid and substituted benzaldehydes under green conditions. The fused 3,4-dihydropyridin-2(1H)- one-ring naphthoquinones have been synthesized with good to high yields in refluxing ethanol as a green reaction medium. This protocol is simple and effective as well as does not involve the assistance of the catalyst, additive, or hazardous solvents.


2004 ◽  
Vol 34 (1) ◽  
pp. 25-32 ◽  
Author(s):  
Uday V. Desai ◽  
D. M. Pore ◽  
R. B. Mane ◽  
S. B. Solabannavar ◽  
P. P. Wadgaonkar

2009 ◽  
Vol 58 (7) ◽  
pp. 1538-1541 ◽  
Author(s):  
B. V. Lichitsky ◽  
A. N. Komogortsev ◽  
R. M. Belyi ◽  
A. A. Dudinov ◽  
M. M. Krayushkin

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