HIT in the head: a systematic review of cerebral venous sinus thrombosis in classical and autoimmune heparin-induced thrombocytopenia

2021 ◽  
Author(s):  
Megan M. J. Bauman ◽  
Ryan M. Naylor ◽  
Eelco F. Wijdicks
Keyword(s):  
Systematic Review ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Heparin Induced Thrombocytopenia ◽  
Venous Sinus Thrombosis

Management of paediatric otogenic cerebral venous sinus thrombosis: a systematic review

2015 ◽  
Vol 40 (6) ◽  
pp. 704-714 ◽  
Author(s):  
B.Y.W. Wong ◽  
S. Hickman ◽  
M. Richards ◽  
P. Jassar ◽  
T. Wilson
Keyword(s):  
Systematic Review ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis

Cerebral venous sinus thrombosis in pregnancy and puerperium: A pooled, systematic review

2017 ◽  
Vol 39 ◽  
pp. 9-15 ◽  
Author(s):  
Ahmed I. Kashkoush ◽  
Henry Ma ◽  
Nitin Agarwal ◽  
David Panczykowski ◽  
Daniel Tonetti ◽  
...  
Keyword(s):  
Systematic Review ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis ◽  
In Pregnancy

Spontaneous heparin-induced thrombocytopenia presenting as cerebral venous sinus thrombosis

2020 ◽  
pp. 10.1212/CPJ.0000000000000805
Author(s):  
Ginette Moores ◽  
Theodore E. Warkentin ◽  
Mohammed A.M. Farooqi ◽  
Stefan D. Jevtic ◽  
Michelle P. Zeller ◽  
...  
Keyword(s):  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Heparin Induced Thrombocytopenia ◽  
Venous Sinus Thrombosis

Endovascular mechanical thrombectomy for cerebral venous sinus thrombosis: a systematic review

2017 ◽  
Vol 9 (11) ◽  
pp. 1086-1092 ◽  
Author(s):  
Adeel Ilyas ◽  
Ching-Jen Chen ◽  
Daniel M Raper ◽  
Dale Ding ◽  
Thomas Buell ◽  
...  
Keyword(s):  
Systematic Review ◽  
Mechanical Thrombectomy ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis ◽  
Endovascular Mechanical Thrombectomy

scholarly journals Successful endovascular therapy for cerebral venous sinus thrombosis accompanied by heparin-induced thrombocytopenia

2020 ◽  
Vol 26 (3) ◽  
pp. 341-345
Author(s):  
Yoshihisa Fukushima ◽  
Kenji Takahashi ◽  
Ichiro Nakahara
Keyword(s):  
Medical Treatment ◽  
Endovascular Therapy ◽  
Sinus Thrombosis ◽  
Venous Drainage ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Heparin Induced Thrombocytopenia ◽  
Venous Sinus Thrombosis ◽  
Excellent Outcome ◽  
Disturbance Of Consciousness

Introduction Heparin-induced thrombocytopenia (HIT) is an immune-mediated complication of heparin exposure. A limited number of studies have reported cerebral venous sinus thrombosis accompanied by heparin-induced thrombocytopenia. Here, we present a case of successful endovascular therapy (EVT) without periprocedural heparinization in this situation. Case presentation A 47-year-old woman taking an oral contraceptive was admitted to our hospital with severe headache to be diagnosed as cerebral venous sinus thrombosis. Initially, she got improved by medical treatment with intravenous unfractionated heparin. However, she rapidly developed disturbance of consciousness and right hemiplegia due to cerebral venous sinus thrombosis accompanied by heparin-induced thrombocytopenia on the 14th hospital day. She underwent emergent EVT by immediate conversion of anticoagulation from heparin to argatroban. Despite a large clot burden, sufficient recanalization and anterograde venous drainage were re-established by combined EVT including aspiration, balloon sinoplasty, and local thrombolysis with urokinase infusion. She got improved immediately after the intervention and discharged home without any neurological sequelae after two months. Conclusion This unique case of cerebral venous sinus thrombosis worsened by occurrence of heparin-induced thrombocytopenia during the treatment finally resulted in excellent outcome highlights effectiveness of emergent endovascular intervention for critical cerebral venous sinus thrombosis resistant to initial medical treatment and of immediate establishment of effective anticoagulant strategy for both of heparin-induced thrombocytopenia and cerebral venous sinus thrombosis. Neuroendovascular therapy for cerebral venous sinus thrombosis using alternative argatroban to heparin for periprocedural anticoagulation might be safe and feasible.

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