Protective effects of fucoidan against 4-nitroquinolin-1-oxide provoked genetic damage in mouse bone marrow cells

2020 ◽  
Vol 27 (25) ◽  
pp. 31760-31766
Author(s):  
Arumugam Ponnan ◽  
Arunkumar Kulanthaiyesu ◽  
Murugan Marudhamuthu ◽  
Kamalakkannan Palanisamy ◽  
Murugan Kadarkarai
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Cells ◽  
Mouse Bone Marrow ◽  
Protective Effects ◽  
Genetic Damage ◽  
Mouse Bone Marrow Cells ◽  
Marrow Cells

Protective effects of indole-3-carbinol on cyclophosphamide-induced clastogenecity in mouse bone marrow cells

2004 ◽  
Vol 23 (5) ◽  
pp. 245-250 ◽  
Author(s):  
Yogeshwer Shukla ◽  
Bhawna Srivastava ◽  
Annu Arora ◽  
L KS Chauhan
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Cells ◽  
Significant Inhibition ◽  
Mouse Bone Marrow ◽  
Protective Effects ◽  
The Status ◽  
Chromosomal Mutations ◽  
Mouse Bone Marrow Cells ◽  
Marrow Cells

Indole-3-carbinol (I3C) is present in many cruciferous vegetables and is known to possess protective properties against chemically induced toxicity and carcinogenesis. In the present study, the antimutagenic potential of I3C has been evaluated using in vivo chromosomal aberration (CA) assay as a cytogenetic end point. Chromosomal analysis was carried out in mouse bone marrow cells following administration of I3C (5 mg/kg; i.p.) for 5 consecutive days. Cyclophosphamide (CP), a well known mutagen, was given at two dose levels of 25 mg/kg b.wt. and 100 mg/kg b.wt., respectively, 24 hours prior to the last dose of I3C. Two groups of five mice each were also injected with CP (25 or 100 mg/kg b.wt.) alone whereas for the vehicle control a group of mice was injected with normal saline only. The results revealed a significant inhibition in the frequencies of CP-induced CAs and aberrant cells in bone marrow cells of I3C-supplemented Swiss albino mice. The antimutagenic potential of I3C towards CP was also evident as the status of mitotic index (MI) was found to show an increment. This study revealed the antigenotoxic potential of I3C against CP- induced chromosomal mutations.

Protective effects of lupeol against benzo[a]pyrene induced clastogenicity in mouse bone marrow cells

2008 ◽  
Vol 52 (10) ◽  
pp. 1117-1120 ◽  
Author(s):  
Sahdeo Prasad ◽  
Vinay Kumar Yadav ◽  
Smita Srivastava ◽  
Yogeshwer Shukla
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Cells ◽  
Mouse Bone Marrow ◽  
Protective Effects ◽  
Mouse Bone Marrow Cells ◽  
Marrow Cells

scholarly journals Brahmarasayana protects against Ethyl methanesulfonate or Methyl methanesulfonate induced chromosomal aberrations in mouse bone marrow cells

2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Kanive Parashiva Guruprasad ◽  
Advait Subramanian ◽  
Vikram Jeet Singh ◽  
Raghavendra Sudheer Kumar Sharma ◽  
Puthiya Mundyat Gopinath ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Chromosomal Aberrations ◽  
Bone Marrow Cells ◽  
Ethyl Methanesulfonate ◽  
Methyl Methanesulfonate ◽  
Mouse Bone Marrow ◽  
Mouse Bone Marrow Cells ◽  
Marrow Cells

scholarly journals Hepatocyte-like cells from directed differentiation of mouse bone marrow cells in vitro1

2005 ◽  
Vol 26 (4) ◽  
pp. 469-476 ◽  
Author(s):  
Xiao-lei SHI ◽  
Yu-dong QIU ◽  
Qiang LI ◽  
Ting XIE ◽  
Zhang-hua ZHU ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Cells ◽  
Mouse Bone Marrow ◽  
Directed Differentiation ◽  
Mouse Bone Marrow Cells ◽  
Marrow Cells

Induction of micronuclei in mouse bone marrow cells: An evaluation of nucleoside analogues used in the treatment of AIDS

1991 ◽  
Vol 18 (3) ◽  
pp. 168-183 ◽  
Author(s):  
Marcia D. Phillips ◽  
Bruce Nascimbeni ◽  
Raymond R. Tice ◽  
Michael D. Shelby ◽  
A. A. Van Zeeland
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Cells ◽  
Nucleoside Analogues ◽  
Mouse Bone Marrow ◽  
Mouse Bone Marrow Cells ◽  
Marrow Cells

J-LEAPS Vaccines Mature Mouse Bone Marrow Cells to Dendritic Cells-1 (DC1) which can Deliver Protective Immunity

2010 ◽  
Vol 135 ◽  
pp. S32
Author(s):  
Patricia Taylor ◽  
Gary Koski ◽  
Erin Bailey ◽  
Daniel Zimmerman ◽  
Ken S. Rosenthal
Keyword(s):  
Bone Marrow ◽  
Dendritic Cells ◽  
Protective Immunity ◽  
Bone Marrow Cells ◽  
Mouse Bone Marrow ◽  
Mature Mouse ◽  
Mouse Bone Marrow Cells ◽  
Marrow Cells
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