Evaluation of a blood-based geroscience biomarker index in a randomized trial of caloric restriction and exercise in older adults with heart failure with preserved ejection fraction

GeroScience ◽  
2022 ◽  
Author(s):  
Jamie N. Justice ◽  
Nicholas M. Pajewski ◽  
Mark A. Espeland ◽  
Peter Brubaker ◽  
Denise K. Houston ◽  
...  
Keyword(s):  
Heart Failure ◽  
Older Adults ◽  
Ejection Fraction ◽  
Randomized Trial ◽  
Caloric Restriction ◽  
Preserved Ejection Fraction

Exercise Intolerance in Older Adults With Heart Failure With Preserved Ejection Fraction

2021 ◽  
Vol 78 (11) ◽  
pp. 1166-1187
Author(s):  
Ambarish Pandey ◽  
Sanjiv J. Shah ◽  
Javed Butler ◽  
Dean L. Kellogg ◽  
Gregory D. Lewis ◽  
...  
Keyword(s):  
Heart Failure ◽  
Older Adults ◽  
Ejection Fraction ◽  
Exercise Intolerance ◽  
Preserved Ejection Fraction

PATTERN OF β-BLOCKER USE FOLLOWING HOSPITALIZATION OF OLDER ADULTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF) FROM THE REGARDS STUDY

2019 ◽  
Vol 73 (9) ◽  
pp. 798
Author(s):  
Brian Yum ◽  
Alexi Archambault ◽  
Jerard Kneifati-Hayek ◽  
Ligong Chen ◽  
Emily Levitan ◽  
...  
Keyword(s):  
Heart Failure ◽  
Older Adults ◽  
Ejection Fraction ◽  
Preserved Ejection Fraction ◽  
Β Blocker ◽  
Regards Study

scholarly journals Reply to: Heart Failure With Preserved Ejection Fraction in Older Adults

2019 ◽  
Vol 68 (3) ◽  
pp. 665-666
Author(s):  
Kenichi Matsushita ◽  
Kazumasa Harada ◽  
Tetsuro Miyazaki ◽  
Takamichi Miyamoto ◽  
Shun Kohsaka ◽  
...  
Keyword(s):  
Heart Failure ◽  
Older Adults ◽  
Ejection Fraction ◽  
Preserved Ejection Fraction

Update on diastolic heart failure or heart failure with preserved ejection fraction in the older adults

2012 ◽  
Vol 45 (1) ◽  
pp. 37-50 ◽  
Author(s):  
Kannayiram Alagiakrishnan ◽  
Maciej Banach ◽  
Linda G. Jones ◽  
Subrata Datta ◽  
Ali Ahmed ◽  
...  
Keyword(s):  
Heart Failure ◽  
Older Adults ◽  
Ejection Fraction ◽  
Diastolic Heart Failure ◽  
Preserved Ejection Fraction

scholarly journals Treating Anemia in Older Adults With Heart Failure With a Preserved Ejection Fraction With Epoetin Alfa

2013 ◽  
Vol 6 (2) ◽  
pp. 254-263 ◽  
Author(s):  
Mathew S. Maurer ◽  
Sergio Teruya ◽  
Bibhas Chakraborty ◽  
Stephen Helmke ◽  
Donna Mancini
Keyword(s):  
Heart Failure ◽  
Older Adults ◽  
Ejection Fraction ◽  
Preserved Ejection Fraction ◽  
Epoetin Alfa

scholarly journals Adaptive support ventilation as an effective treatment option for central sleep apnea in an older adult with heart failure with preserved ejection fraction: a case report

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Yuriko Hajika ◽  
Yuji Kawaguchi ◽  
Kenji Hamazaki ◽  
Yasuro Kumeda
Keyword(s):  
Heart Failure ◽  
Older Adults ◽  
Sleep Apnea ◽  
Ejection Fraction ◽  
Daytime Sleepiness ◽  
Sleep Disordered Breathing ◽  
Central Sleep Apnea ◽  
Preserved Ejection Fraction ◽  
Adaptive Support Ventilation ◽  
Adaptive Support

Abstract Background Adaptive support ventilation (ASV) is a proposed treatment option for central sleep apnea (CSA). Although the effectiveness of ASV remains unclear, some studies have reported promising results regarding the use of ASV in patients with heart failure with preserved ejection fraction (HfpEF). To illustrate the importance of suspecting and diagnosing sleep-disordered breathing (SDB) in older adults unable to recognize symptoms, we discuss a case in which ASV was effective in a patient with CSA and HfpEF, based on changes in the Holter electrocardiogram (ECG). Case presentation. An 82-year-old man presented to our hospital with vomiting on April 19, 2021. Approximately 10 years before admission, he was diagnosed with type 1 diabetes mellitus and recently required full support from his wife for daily activities due to cognitive dysfunction. Two days before admission, his wife was unable to administer insulin due to excessively high glucose levels, which were displayed as “high” on the patient’s glucose meter; therefore, we diagnosed the patient with diabetic ketoacidosis. After recovery, we initiated intensive insulin therapy for glycemic control. However, the patient exhibited excessive daytime sleepiness, and numerous premature ventricular contractions were observed on his ECG monitor despite the absence of hypoglycemia. As we suspected sleep-disordered breathing (SDB), we performed portable polysomnography (PSG), which revealed CSA. PSG revealed a central type of apnea and hypopnea due to an apnea–hypopnea index of 37.6, which was > 5. Moreover, the patient had daytime sleepiness; thus, we diagnosed him with CSA. We performed ASV and observed its effect using portable PSG and Holter ECG. His episodes of apnea and hypopnea were resolved, and an apparent improvement was confirmed through Holter ECG. Conclusion Medical staff should carefully monitor adult adults for signs of or risk factors for SDB to prevent serious complications. Future studies on ASV should focus on older patients with arrhythmia, as the prevalence of CSA may be underreported in this population and determine the effectiveness of ASV in patients with HfpEF, especially in older adults.

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