Postmortem distribution of AB-CHMINACA, 5-fluoro-AMB, and diphenidine in body fluids and solid tissues in a fatal poisoning case: usefulness of adipose tissue for detection of the drugs in unchanged forms

2014 ◽  
Vol 33 (1) ◽  
pp. 45-53 ◽  
Author(s):  
Koutaro Hasegawa ◽  
Amin Wurita ◽  
Kayoko Minakata ◽  
Kunio Gonmori ◽  
Hideki Nozawa ◽  
...  
2014 ◽  
Vol 33 (1) ◽  
pp. 141-147 ◽  
Author(s):  
Koutaro Hasegawa ◽  
Amin Wurita ◽  
Kayoko Minakata ◽  
Kunio Gonmori ◽  
Hideki Nozawa ◽  
...  

2014 ◽  
Vol 16 (5) ◽  
pp. 241-246 ◽  
Author(s):  
Amin Wurita ◽  
Koutaro Hasegawa ◽  
Kayoko Minakata ◽  
Kunio Gonmori ◽  
Hideki Nozawa ◽  
...  

2015 ◽  
Vol 33 (2) ◽  
pp. 380-387 ◽  
Author(s):  
Koutaro Hasegawa ◽  
Amin Wurita ◽  
Kayoko Minakata ◽  
Kunio Gonmori ◽  
Hideki Nozawa ◽  
...  

2015 ◽  
Vol 17 (5) ◽  
pp. 394-400 ◽  
Author(s):  
Koutaro Hasegawa ◽  
Amin Wurita ◽  
Kayoko Minakata ◽  
Kunio Gonmori ◽  
Hideki Nozawa ◽  
...  

Author(s):  
Jovana Jagodić ◽  
Branislav Rovčanin ◽  
Slavica Borković-Mitić ◽  
Ljiljana Vujotić ◽  
Viacheslav Avdin ◽  
...  

2013 ◽  
Vol 31 (2) ◽  
pp. 328-332 ◽  
Author(s):  
Takeshi Saito ◽  
Akira Namera ◽  
Motoki Osawa ◽  
Hiromichi Aoki ◽  
Sadaki Inokuchi

2021 ◽  
Vol 36 (3) ◽  
pp. 199-203
Author(s):  
Michael Kraemer ◽  
Cornelius Hess ◽  
Alexandra Maas ◽  
Burkhard Madea ◽  
Andras Bilkei-Gorzo ◽  
...  

Abstract Objectives In a previous investigation we searched for the occurrence of palmitic acid ester compounds of delta9-tetrahydrocannabinol (THC) and its primary metabolite 11-hydroxy-delta9-THC (11-OH-THC) in human body fluids and tissues (THC palmitic acid monoester [THC-Pal] and 11-OH-THC palmitic acid diester [11-OH-THC-DiPal]). As those esters could not be detected in various human body fluids (e.g. blood) or tissues (e.g. adipose tissue) we extended the investigation analyzing adipose tissue samples of mice previously given synthetic THC or a cannabis extract. Methods In total, 48 adipose tissue samples previously tested positive for THC by means of a liquid chromatographic triple quadrupole mass spectrometric (LC-QQQ-MS) method were analyzed for the presence of THC-Pal and 11-OH-THC-DiPal by means of LC-QQQ-MS. Results THC-Pal and 11-OH-THC-DiPal were not detected among the adipose tissue samples analyzed despite the presence of high THC concentrations within the adipose tissue. THC concentrations in adipose tissue were in a range of approximately 7–2,595 ng/g (median: 468 ng/g, average: 704 ng/g). Conclusions A (site-specific) synthesis of 11-OH-THC palmitic acid monoesters (11-hydroxy-delta9-THC-1-palmitate and 11-palmitoyloxy-delta9-THC) still remains to be done. After synthesis of these monoesters, their presence in the body fluids and tissues after THC administration should be investigated.


2004 ◽  
Vol 139 (2-3) ◽  
pp. 191-194 ◽  
Author(s):  
G. Boatto ◽  
M. Nieddu ◽  
A. Carta ◽  
A. Pau ◽  
S. Lorenzoni ◽  
...  

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