Spontaneous contractions of isolated rat portal vein under temperature perturbations

2010 ◽  
Vol 48 (9) ◽  
pp. 887-894 ◽  
Author(s):  
Vesna Vuksanović ◽  
Vera Gal ◽  
Mirjana M. Platiša ◽  
Ljiljana Gojković-Bukarica
Keyword(s):  
Portal Vein ◽  
Rat Portal Vein ◽  
Spontaneous Contractions ◽  
Isolated Rat

Possible interactions between neurotensin and prostaglandins in the isolated rat portal vein

Life Sciences ◽  
1980 ◽  
Vol 27 (3) ◽  
pp. 259-267 ◽  
Author(s):  
F. Rioux ◽  
R. Quirion ◽  
M.A. Leblanc ◽  
D. Regoli ◽  
S. St-Pierre
Keyword(s):  
Portal Vein ◽  
Rat Portal Vein ◽  
Isolated Rat

Modifications evoked by piretanide in the mechanical activity of cardiovascular tissues

1985 ◽  
Vol 63 (4) ◽  
pp. 283-286
Author(s):  
J. L. Lacuara ◽  
R. D. Ruiz ◽  
M. Fiol de Cuneo
Keyword(s):  
Portal Vein ◽  
Contractile Activity ◽  
Mechanisms Of Action ◽  
Mechanical Activity ◽  
Vascular Tissues ◽  
Cardiovascular Tissues ◽  
Rat Portal Vein ◽  
Isolated Rat

The effects of piretanide upon mechanical activity and pharmacological reactivity of vascular and myocardial tissues from normotensive rats were investigated. Magnitude of phasic contractions of isolated rat portal vein was diminished by the drug in a dose-related manner; contractile depression induced by piretanide (10−4 M) was less in the presence of insulin (0.1 U/mL), glucose (22 mM) or pyruvate (5 mM). Responses to KCl (90 mM), or norepinephrine (2.5 × 10−5 M) were also reduced. Contractile activity of atria and ventricle strips was diminished only when piretanide reached 10−4 M. Results support direct actions of piretanide upon cardiac and vascular tissues. Possible mechanisms of action are discussed.

Sign in / Sign up

Export Citation Format

Share Document