Lagged segmented Poincaré plot analysis for risk stratification in patients with dilated cardiomyopathy

Summary Background: The prognostic value of heart rate variability in patients with dilated cardiomyopathy (DCM) is limited and does not contribute to risk stratification although the dynamics of ventricular repolarization differs considerably between DCM patients and healthy subjects. Neither linear nor nonlinear methods of heart rate variability analysis could discriminate between patients at high and low risk for sudden cardiac death. Objective: The aim of this study was to analyze the suitability of the new developed segmented Poincaré plot analysis (SPPA) to enhance risk stratification in DCM. Methods: In contrast to the usual applied Poincaré plot analysis the SPPA retains nonlinear features from investigated beat-to-beat interval time series. Main features of SPPA are the rotation of cloud of points and their succeeded variability depended segmentation. Results: Significant row and column probabilities were calculated from the segments and led to discrimination (up to p < 0.005) between low and high risk in DCM patients. Conclusion: For the first time an index from Poincaré plot analysis of heart rate variability was able to contribute to risk stratification in patients suffering from DCM.

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Comparison of nonlinear methods symbolic dynamics, detrended fluctuation, and Poincaré plot analysis in risk stratification in patients with dilated cardiomyopathy

Chaos An Interdisciplinary Journal of Nonlinear Science ◽

10.1063/1.2404633 ◽

2007 ◽

Vol 17 (1) ◽

pp. 015120 ◽

Cited By ~ 45

Author(s):

Andreas Voss ◽

Rico Schroeder ◽

Sandra Truebner ◽

Matthias Goernig ◽

Hans Reiner Figulla ◽

...

Keyword(s):

Risk Stratification ◽

Dilated Cardiomyopathy ◽

Symbolic Dynamics ◽

Poincaré Plot ◽

Nonlinear Methods ◽

Plot Analysis ◽

Detrended Fluctuation

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Arrhythmic Risk Stratification in Nonischemic Dilated Cardiomyopathy

Case Medical Research ◽

10.31525/ct1-nct04246450 ◽

2020 ◽

Author(s):

Keyword(s):

Risk Stratification ◽

Dilated Cardiomyopathy ◽

Nonischemic Dilated Cardiomyopathy

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QT variability analysis for risk stratification in patients with dilated cardiomyopathy

2014 8th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) ◽

10.1109/esgco.2014.6847509 ◽

2014 ◽

Author(s):

Claudia Fischer ◽

Andrea Seeck ◽

Rico Schroeder ◽

Matthias Goernig ◽

Alexander Schirdewan ◽

...

Keyword(s):

Risk Stratification ◽

Dilated Cardiomyopathy ◽

Variability Analysis ◽

Qt Variability

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Sudden Cardiac Death in Hereditary Dilated Cardiomyopathy

Sudden Cardiac Death ◽

10.5772/intechopen.91702 ◽

2020 ◽

Author(s):

Marianna Leopoulou ◽

Jo Ann LeQuang ◽

Joseph V. Pergolizzi ◽

Peter Magnusson

Keyword(s):

Sudden Cardiac Death ◽

Left Ventricle ◽

Sudden Death ◽

Risk Stratification ◽

Dilated Cardiomyopathy ◽

Cardiac Death ◽

Disease Risk ◽

Systolic Dysfunction ◽

Preventive Strategies ◽

Genetic Origin

Dilated cardiomyopathy (DCM) is characterized by the phenotype of a dilated left ventricle with systolic dysfunction. It is classified as hereditary when it is deemed of genetic origin; more than 50 genes are reported to be related to the condition. Symptoms include, among others, dyspnea, fatigue, arrhythmias, and syncope. Unfortunately, sudden cardiac death may be the first manifestation of the disease. Risk stratification regarding sudden death in hereditary DCM as well as preventive management poses a challenge due to the heterogeneity of the disease. The purpose of this chapter is to present the epidemiology, risk stratification, and preventive strategies of sudden cardiac death in hereditary DCM.

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