Head and Neck Low-Grade Fibromyxoid Sarcoma: A Clinicopathologic Study of 15 Cases

Author(s):  
Sandra Gjorgova Gjeorgjievski ◽  
Karen Fritchie ◽  
Judith Jebastin Thangaiah ◽  
Andrew L. Folpe ◽  
Nasir Ud Din
2018 ◽  
Vol 69 (3) ◽  
pp. 219-225 ◽  
Author(s):  
Andrea Sambri ◽  
Alberto Righi ◽  
Gianmarco Tuzzato ◽  
Davide Donati ◽  
Giuseppe Bianchi

2021 ◽  
Vol 14 (5) ◽  
pp. e237083
Author(s):  
Muhammad Hammad Deewani ◽  
Muhammad Hassan Danish ◽  
Muhammad Sohail Awan ◽  
Nasir Ud Din

Low-grade fibromyxoid sarcoma (LGFMS) is an uncommon soft-tissue malignancy. LGFMS preferentially affects trunks and extremities of young adults; however, occasional cases have been reported in different sites of head and neck region including oral cavity, larynx and oropharynx. LGFMS usually exhibit areas of collagenised and myxoid stroma with appearance of spindle cells in whorling pattern. It is a challenge to diagnose it accurately as most of the time it is misdiagnosed as benign neoplastic entity of spindle cells. There have been only few isolated cases of LGFMS reported in head and neck region and LGFMS originating from the parapharyngeal space has never been reported before. We recently experienced a case of low grade fibomyxoid sarcoma in parapharyngeal space of neck. LGFMS have the propensity to locally recur and to metastasise. Due to its rarity in head and neck region, there are no well-established treatment and follow-up guidelines.


2015 ◽  
Vol 10 (2) ◽  
pp. 161-166 ◽  
Author(s):  
Morgan L. Cowan ◽  
Lester D. Thompson ◽  
Marino E. Leon ◽  
Justin A. Bishop

2015 ◽  
Vol 28 (7) ◽  
pp. 944-953 ◽  
Author(s):  
Michiel P J van der Horst ◽  
Zlatko Marusic ◽  
Jason L Hornick ◽  
Boštjan Luzar ◽  
Thomas Brenn

2009 ◽  
Vol 27 (9) ◽  
pp. 375-380 ◽  
Author(s):  
Eriko Maeda ◽  
Satoshi Ohta ◽  
Takeyuki Watadani ◽  
Akiteru Goto ◽  
Atsushi Nakajima ◽  
...  

2006 ◽  
Vol 130 (9) ◽  
pp. 1358-1360 ◽  
Author(s):  
Stephen E. Vernon ◽  
Pablo A. Bejarano

Abstract Low-grade fibromyxoid sarcomas are uncommon deep soft tissue neoplasms first described by Evans in 1987. They exhibit a deceptively benign appearance, with a whorled or linear arrangement of spindle-shaped cells showing few to absent mitoses. A characteristic, but not specific, feature is the presence of areas of myxoid stroma. Recurrences are common, and late metastases have been recorded. A closely related but morphologically distinct tumor, the so-called hyalinizing spindle cell tumor with giant rosettes, has also been described; both neoplasms share the same cytogenetic abnormality, a balanced translocation resulting in a FUS/CREB3L2 fusion gene. Because of similar clinical behavior and the common cytogenetic abnormality, some authors prefer to consider both lesions as a single entity within the spectrum of low-grade sarcomas.


2018 ◽  
Vol 12 ◽  
pp. 24-28
Author(s):  
Yasuaki Tsuchida ◽  
Yoshitane Tsukamoto ◽  
Hiroyuki Futani ◽  
Shunsuke Kumanishi ◽  
Takahiro Watanabe ◽  
...  

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