scholarly journals Controlled downregulation of the cannabinoid CB1 receptor provides a promising approach for the treatment of obesity and obesity-derived type 2 diabetes

2015 ◽  
Vol 21 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Dai Lu ◽  
Rachel Dopart ◽  
Debra A. Kendall
Keyword(s):  
Type 2 Diabetes ◽  
Cb1 Receptor ◽  
Cannabinoid Cb1 Receptor ◽  
Treatment Of Obesity

Naltrexone/bupropion for the treatment of obesity and obesity with Type 2 diabetes

2016 ◽  
Vol 12 (2) ◽  
pp. 129-138 ◽  
Author(s):  
Caroline M Apovian
Keyword(s):  
Type 2 Diabetes ◽  
Treatment Of Obesity

Drug Treatment of Obesity in Type 2 Diabetes Mellitus

1990 ◽  
Vol 7 (2) ◽  
pp. 99-104 ◽  
Author(s):  
M. A. Carpenter ◽  
H. J. Bodansky
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Drug Treatment ◽  
Treatment Of Obesity

MC4R as a Target for Pharmacotherapeutic Treatment of Obesity and Type 2 Diabetes

2020 ◽  
pp. 935-946
Author(s):  
Juliana Pereira Lopes Gonçalves ◽  
Daniel Palmer ◽  
Morten Meldal
Keyword(s):  
Type 2 Diabetes ◽  
Treatment Of Obesity

scholarly journals Advances in Acupuncture and its Associated Therapies for the Prevention and Treatment of Obesity Type 2 Diabetes Mellitus

2020 ◽  
Vol 4 (5) ◽  
Author(s):  
Kaiya Zhang ◽  
Yuanyuan Ren ◽  
Yanyan Zhou
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Disease ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Clinical Practice ◽  
Clinical Symptoms ◽  
Embedding Therapy ◽  
Prevention And Treatment ◽  
Treatment Of Obesity

Obesity type 2 diabetes mellitus is a common metabolic disease in clinical practice, and its prevalence is increasing rapidly with the aging of the population and changes in lifestyle. Acupuncture, as a distinctive therapy, has its unique advantages in the treatment of obesity type 2 diabetes and has an irreplaceable role in a variety of treatment methods. The author organized the literature on acupuncture and its related therapies to prevent and treat obesity type 2 diabetes in recent years and found that acupuncture and its associated therapies to prevent and treat obesity type 2 diabetes mainly include: simple acupuncture, electroacupuncture, acupoint catgut embedding therapy, auricular-plaster therapy and other treatments, all of which can safely and effectively improve clinical symptoms, acupuncture and its related therapies to treat obesity type 2 diabetes has a broad prospect, worthy of further clinical promotion.

scholarly journals Methods of treatment of obesity in patients with type 2 diabetes

2021 ◽  
Vol 77 (7) ◽  
pp. 442-450
Author(s):  
Igor Pasek ◽  
Lidia Wiska ◽  
Patrycja Kopytko ◽  
Bolesław Banach
Keyword(s):  
Type 2 Diabetes ◽  
Treatment Of Obesity ◽  
Methods Of Treatment

OXM-104, a potential candidate for the treatment of obesity, NASH and type 2 diabetes

2021 ◽  
Author(s):  
Ashref Kayed ◽  
Simone Melander ◽  
Kim Andreassen ◽  
Morten Karsdal ◽  
Kim Henriksen
Keyword(s):  
Type 2 Diabetes ◽  
Receptor Agonist ◽  
Therapeutic Option ◽  
Treatment Options ◽  
Potential Candidate ◽  
Alcoholic Fatty Liver ◽  
Glucagon Like Peptide 1 ◽  
Treatment Of Obesity ◽  
Long Acting

Abstract Obesity-related metabolic disorders, including non-alcoholic fatty liver disease and its more progressive form non-alcoholic steatohepatitis, are causing an increased health burden, especially due to the lack of approved treatment options. Using preclinical models of NASH, obesity, and type 2 diabetes, we investigated the effects of a long-acting glucagon-like peptide-1(GLP-1) and glucagon (GCG) receptor agonist OXM-104 head to head with once-daily GLP-1/GCG receptor agonist cotadutide and once-weekly GLP-1 receptor agonist semaglutide. OXM-104, cotadutide, and semaglutide elicited marked reductions in body weight and improved glucose control. In contrast, hepatoprotective effects, i.e., reductions in steatosis and fibrosis, as well as liver fibrosis biomarkers, were more prominent with OXM-104 and cotadutide than effects seen with semaglutide. This is demonstrated by improved NAFLD activity score (NAS) by OXM-104 and cotadutide which underlines the importance of the GCG receptor. Thus, these results underline the potential of OXM-104 as a promising therapeutic option for the resolution of NASH, but also as a therapeutic option for type 2 diabetes and obesity.

Ketogenic diets as treatment of obesity and type 2 diabetes mellitus

2020 ◽  
Vol 21 (3) ◽  
pp. 381-397 ◽  
Author(s):  
Felipe F. Casanueva ◽  
Marco Castellana ◽  
Diego Bellido ◽  
Pierpaolo Trimboli ◽  
Ana I. Castro ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Ketogenic Diets ◽  
Treatment Of Obesity
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