Eudesmanolides from Taraxacum mongolicum and their inhibitory effects on the production of nitric oxide

2011 ◽  
Vol 34 (1) ◽  
pp. 37-41 ◽  
Author(s):  
Young-Hee Kim ◽  
Soo-Jin Choo ◽  
In-Ja Ryoo ◽  
Jong-Seok Ahn ◽  
Ick-Dong Yoo
1999 ◽  
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pp. 1034-1040 ◽  
Author(s):  
Alison M Emsley ◽  
Jamie Y Jeremy ◽  
Guiomar N Gomes ◽  
Gianni D Angelini ◽  
Frances Plane

2021 ◽  
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pp. 230-238
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Jun Gu Kim ◽  
Jin Woo Lee ◽  
Thi Phuong Linh Le ◽  
Jae Sang Han ◽  
Haeun Kwon ◽  
...  

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pp. 1934578X1501000 ◽  
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Nilubon Sornkaew ◽  
Yuan Lin ◽  
Fei Wang ◽  
Guolin Zhang ◽  
Ratchanaporn Chokchaisiri ◽  
...  

Eight new diarylheptanoids, a 1.2:1 mixture of (3S)- and (3 R)-1-(4-hydroxyphenyl)-7-phenyl-(4 E,6 E)-4,6-heptadien-3-ol (1a and 1b), a racemic mixture of (3S)- and (3 R)-1-(4-hydroxyphenyl)-3-methoxy-7-phenyl-(4 E,6 E)-4,6-heptadiene (2a and 2b), a ca. 1:1 mixture of (3S)- and (3 R)-1-(4-hydroxy-3-methoxyphenyl)-3-methoxy-7-phenyl)-(4 E,6 E)-4,6-heptadiene (3a and 3b), 3-acetoxy-1-(3,4-dihydroxyphenyl)-7-phenylheptan-5-ol (4), (3 R)-1-(4,5-dihydroxyphenyl)-7-phenyl-(6 E)-6-hepten-3,2′-epoxide (5), and thirteen known diarylheptanoids, 6-12, a 3:1 mixture of 13a and 13b, and 14-17, were isolated from the rhizomes of Curcuma comosa from Sakon Nakhon, northeastern part of Thailand. The isolated compounds were evaluated for their antiinflammatory activities on the inhibition of lipopolysaccharide-induced nitric oxide production in macrophage RAW 264.7 cells and the diarylheptanoids 1a and 1b mixture and 14 exhibited potent inhibitory activity.


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