Schisandrin A reverses doxorubicin-resistant human breast cancer cell line by the inhibition of P65 and Stat3 phosphorylation

Breast Cancer ◽  
2017 ◽  
Vol 25 (2) ◽  
pp. 233-242 ◽  
Author(s):  
Zong-Lin Zhang ◽  
Qing-Cheng Jiang ◽  
Su-Rong Wang
2003 ◽  
Vol 278 (44) ◽  
pp. 43363-43372 ◽  
Author(s):  
Jun Kawagoe ◽  
Masahide Ohmichi ◽  
Toshifumi Takahashi ◽  
Chika Ohshima ◽  
Seiji Mabuchi ◽  
...  

2021 ◽  
Vol 66 (1) ◽  
pp. 65-71
Author(s):  
Hung Nguyen Phi ◽  
Toan Tran Quoc ◽  
Tuan Nguyen Anh ◽  
Vy Trinh Ngoc Thao ◽  
Yen Ngo Thi Ngoc ◽  
...  

Three alkaloids (named rutaecarpine (1), evodiamine (2), schinifoline (3) and one phenylpropanoid, integrifoliodiol (4)) have been isolated from the EtOAc extract of the fruits of Tetradium ruticarpum (A. Juss.) T. G. Hartley collected in Lang Son province. Their structures have been identified by using 1D and 2D NMR spectroscopies. All four compounds were tested for their cytotoxicity against the human breast cancer cell line (MCF-7) and tamoxifen-resistant breast cancer cell line (MCF\TAMR). The results showed that rutaecarpine (1) inhibited the growth of MCF7 and MCF\TAMR with its IC50 values of 41.2 and 64.6 µM, respectively. In addition, compounds 1, 2, and 4 showed moderate activity toward MCF-7 cell line.


2003 ◽  
Vol 32 (8) ◽  
pp. 1595-1603 ◽  
Author(s):  
J. Vassy ◽  
S. Portet ◽  
M. Beil ◽  
G. Millot ◽  
F. Fauvel-Lafève ◽  
...  

2011 ◽  
Vol 205 ◽  
pp. S80
Author(s):  
C. Ventura ◽  
M.A. Núñez ◽  
V. Gaido ◽  
D. Martinel Lamas ◽  
A.S. Randi ◽  
...  

2008 ◽  
Vol 29 (10) ◽  
pp. 1233-1239 ◽  
Author(s):  
Xiao-yong LEI ◽  
Shu-qiong YAO ◽  
Xu-yu ZU ◽  
Ze-xiang HUANG ◽  
Li-juan LIU ◽  
...  

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