An autopsy case of primary jejunal pouch cancer which protruded from the abdominal wall 14 years after total gastrectomy for gastric cancer

2020 ◽  
Vol 13 (6) ◽  
pp. 1091-1095
Author(s):  
Yuki Kanayama ◽  
Hitoshi Takagi ◽  
Satoshi Takakusagi ◽  
Yozo Yokoyama ◽  
Kazuko Kizawa ◽  
...  
2020 ◽  
Vol 13 (1) ◽  
pp. 225-232
Author(s):  
Takamichi Yokoe ◽  
Michio Sato ◽  
Masashi Yahagi ◽  
Murat Dogru ◽  
Hiroto Fujisaki ◽  
...  

We report the case of a 65-year-old male who developed heterochronous local recurrences of gastric cancer in the jejunal pouch (J-pouch) four times after total gastrectomy. He underwent total gastrectomy, J-pouch, and Roux-en-Y reconstruction for stage II gastric cancer in 2005. Four local recurrences appeared on the esophago-jejunal anastomosis, the suture line within the pouch, the esophago-jejunal anastomosis, and the anastomosis between the jejunum and Y-loop, which were resected by partial excision or endoscopic submucosal dissection. Suture line recurrence of gastric cancer is rare. The common features for each recurrence included the surgically negative resection margins, observation of the same histopathological subtype, absence of remote metastasis or peritoneal seeding, and the recurrence on the anastomotic suture line, suggesting that the cause of recurrence was the implantation of exfoliated cancer cells probably in the suture line. However, there is no established procedure for preventing implantation recurrence currently, the effectiveness of lumen lavage is suggested.


2005 ◽  
Vol 38 (6) ◽  
pp. 585-591
Author(s):  
Yasuyuki Kawachi ◽  
Takeaki Shimizu ◽  
Keiya Nikkuni ◽  
Atsushi Nishimura ◽  
Kazuhiko Tsunoda ◽  
...  

2021 ◽  
Author(s):  
Soomin An ◽  
Wankyu Eo ◽  
YounJung Kim

Abstract Background: This study aimed to evaluate the prognostic potential of skeletal muscle mass and muscle quality at the level of the third lumbar vertebra (L3) using computerized tomography (CT) images in patients with stage I–III gastric cancer (GC) who underwent curative gastric resection.Methods: Patients with stage I–III GC who underwent curative gastric resection between October 2006 and June 2014 were enrolled in this study. Demographic and clinical parameters were collected and analyzed. The muscle-related parameters (MRPs), such as the area of total abdominal wall musculature (SMA), area of paraspinal muscle (PMA), mean muscle attenuation (MA) within the total abdominal wall musculature (SMMA), and MA in the paraspinal muscle (PMMA), were measured at the L3 level using CT images. The Kaplan-Meier curve analyses and Cox proportional hazards model were applied to the MRPs, demographic, and clinical parameters to explore the overall survival (OS) and disease-free survival (DFS).Results: Overall, data from 339 patients (233 men and 116 women) were analyzed in this study. In the multivariate Cox model, the elderly (hazard ratio [HR] 2.08, 95% confidence interval [CI] 1.30–3.32, p=0.002), total gastrectomy (HR 2.14, 95% CI 1.32–3.48, p=0.002), stage (HR 3.41, 95% CI 2.10–5.54, p<0.001), perineural invasion (HR 2.01, 95% CI 1.02–3.93, p=0.042), prognostic nutritional index (PNI) (HR 0.91, 95% CI 0.88–0.95, p<0.001), and PMMA (HR 2.36, 95% CI 1.47–3.78), p<0.001) were prognostic factors for OS. Similarly, the elderly (HR 1.68, 95% CI 1.09–2.59, p=0.018), total gastrectomy (HR 2.16, 95% CI 1.37–3.38, p<0.001, stage (HR 4.16, 95% CI 2.64–6.54, p<0.001), PNI (HR 0.91, 95% CI 0.87–0.94, p<0.001), and PMMA (HR 2.22, 95% CI 1.42–3.47, p<0.001) were prognostic factors for DFS.Conclusions: PMMA is suggested as a determinant of OS and DFS in stage I through III GC patients who underwent gastrectomy. Because PMMA is a newly characterized parameter in GC, external validation before clinical applications is a prerequisite.


1999 ◽  
Vol 32 (4) ◽  
pp. 978-982
Author(s):  
Yasumasa Kondoh ◽  
Yasuo Kajiura ◽  
Kenji Nakamura ◽  
Masao Miyaji ◽  
Kyoji Ogoshi ◽  
...  

1999 ◽  
Vol 2 (3) ◽  
pp. 194-197 ◽  
Author(s):  
Kazuya Miyoshi ◽  
Sadanori Fuchimoto ◽  
Toshihide Ohsaki ◽  
Tatsuhiko Sakata ◽  
Isao Takeda ◽  
...  

2019 ◽  
Vol 12 (2) ◽  
pp. 671-680
Author(s):  
Hidenori Maki ◽  
Yasuhiro Yuasa ◽  
Satoshi Fujiwara ◽  
Mizuki Fukuta ◽  
Taihei Takeuchi ◽  
...  

Conversion surgery has been reported but few cases have undergone surgical R0 resection after second-line chemotherapy. We report a case of an unresectable locally advanced gastric cancer in a patient who finally underwent the operation (R0) after second-line chemotherapy. The 77-year-old male was diagnosed with gastric cancer (cT4 [SI; Skin, Liver] N0M0 c Stage IIIA) with invasion to the skin of the abdominal wall, and chemotherapy was initially performed because of his poor performance status and due to the large defect in the abdominal wall that might occur if an operation was performed. Partial response (PR) was observed after S-1+CDDP (SP) therapy, which was then stopped after which progressive disease (PD) was observed. Ramucirumab+Paclitaxel (RAM/PTX) therapy was chosen as second-line therapy, and PR was obtained again, following which total gastrectomy was performed (D2 dissection of lymph nodes, Roux-en-Y reconstruction, and combined resection of the partial skin and the affected region of the liver). At 30 months postoperatively, no recurrence has occurred and the patient is alive after the operation without chemotherapy.


Sign in / Sign up

Export Citation Format

Share Document