scholarly journals Difficulty in differentiating between IgG4-related hepatic inflammatory pseudotumor and intrahepatic cholangiocarcinoma

2020 ◽  
Author(s):  
Ai Hamano ◽  
Reiko Yamada ◽  
Kazunari Kurata ◽  
Junya Tsuboi ◽  
Hiroyuki Inoue ◽  
...  
Keyword(s):  
Liver Biopsy ◽  
Intrahepatic Cholangiocarcinoma ◽  
Inflammatory Pseudotumor ◽  
Detailed Examination ◽  
Carbohydrate Antigen ◽  
Biliary Duct ◽  
Imaging Findings ◽  
Left Lateral Segment ◽  
Enhanced Computed Tomography ◽  
Hepatic Inflammatory Pseudotumor

Abstract A 71-year-old man on prednisolone for immunoglobulin (Ig) G4-related renal disease showed increased carbohydrate antigen (CA) 19–9 level; abdominal enhanced computed tomography (CT) showed a lesion in the left lateral segment and dilatation of the peripheral biliary duct. He was referred to our hospital for detailed examination for suspected intrahepatic cholangiocarcinoma. CT and magnetic resonance imaging findings were similar to those for intrahepatic cholangiocarcinoma. However, endoscopic retrograde cholangiopancreatography showed a smooth narrowing of the bile duct which suggested inflammatory disease. Liver biopsy was performed; IgG4-related hepatic inflammatory pseudotumor (IPT) was diagnosed. IgG4-related hepatic IPTs are rare diseases that develop in association with the development of sclerosing cholangitis. Most of these lesions develop in the hepatic hilum and the imaging findings of these tumors are similar to those of hilar cholangiocarcinomas. Thus, hepatic IPTs are difficult to differentiate from malignancy; in some cases, surgical resection has been considered for establishing the diagnosis. In the present case, we could diagnose hepatic IPT on the basis of liver biopsy, which is the recommended approach in cases of suspected hepatic IPT.

scholarly journals Hepatic Epithelioid Hemangioendothelioma Presenting Synchronously with Hepatocellular Carcinoma

2021 ◽  
pp. 344-351
Author(s):  
Hiroki Kanno ◽  
Toshihiro Sato ◽  
Ryuta Midorikawa ◽  
Satoki Kojima ◽  
Shogo Fukutomi ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Carbohydrate Antigen ◽  
Epithelioid Hemangioendothelioma ◽  
Arterial Phase ◽  
Rapid Progression ◽  
Imaging Findings ◽  
Liver Segment ◽  
Contrast Enhanced ◽  
Well Differentiated ◽  
Enhanced Computed Tomography

Hepatic epithelioid hemangioendothelioma (EHE) is a rare malignant tumor with unknown pathogenesis. Herein, we report a case of a hepatic EHE presenting synchronously with a hepatocellular carcinoma (HCC). To the best of our knowledge, this is the second case report of synchronous hepatic EHE and HCC. An 84-year-old man presented with back pain. During examination, a tumor in liver segment 3 was coincidentally detected. Tumor marker (carbohydrate antigen 19-9, alpha-fetoprotein, and protein induced by vitamin K absence or antagonist-II) levels were elevated. Contrast-enhanced computed tomography revealed perinodular enhancement in the arterial and portal phases. Another tumor was detected in liver segment 2, which was homogeneously enhanced in the arterial phase, followed by washout in the portal and late phases. Based on these imaging findings, we diagnosed the tumor in segment 3 as a solitary cholangiocellular carcinoma and the tumor in segment 2 as a solitary HCC. Lateral sectionectomy of the liver was performed. Microscopically, spindle-shaped and epithelioid cells were present in the tumor in segment 3. On immunohistochemistry, the tumor cells were positive for CD31 and CD34, focally positive for D2-40, and negative for AE1/AE3. Therefore, the tumor in segment 3 was ultimately diagnosed as an EHE and the tumor in segment 2 as a well-differentiated HCC. Preoperative diagnosis of EHE is difficult owing to the lack of specific findings. Intratumoral calcification, halo sign, and lollipop sign are occasionally found in EHE and are useful imaging findings for diagnosis. Clinical behavior is unpredictable, ranging from indolent growth to rapid progression. Clinical or pathological predictors of the course of EHE are urgently required.

Intrahepatic Cholangiocarcinoma Mimicking Hepatic Inflammatory Pseudotumor

2007 ◽  
Vol 11 (3) ◽  
pp. 398-402 ◽  
Author(s):  
Kumiko Kitajima ◽  
Hiroaki Shiba ◽  
Takuya Nojiri ◽  
Tadashi Uwagawa ◽  
Yuichi Ishida ◽  
...  
Keyword(s):  
Intrahepatic Cholangiocarcinoma ◽  
Inflammatory Pseudotumor ◽  
Hepatic Inflammatory Pseudotumor

scholarly journals A Case of Hepatic Inflammatory Pseudotumor Mimicking Intrahepatic Cholangiocarcinoma

2018 ◽  
Vol 43 (2) ◽  
pp. 253-257
Author(s):  
Kyohei Abe ◽  
Yasuro Futagawa ◽  
Tomoyoshi Okamoto ◽  
Masaru Kanehira ◽  
Katsuhiko Yanaga
Keyword(s):  
Intrahepatic Cholangiocarcinoma ◽  
Inflammatory Pseudotumor ◽  
Hepatic Inflammatory Pseudotumor

Hepatic Inflammatory Pseudotumor Mimicking Intrahepatic Cholangiocarcinoma: Report of a Case

Surgery Today ◽  
2003 ◽  
Vol 33 (9) ◽  
pp. 714-717 ◽  
Author(s):  
Keisuke Inaba ◽  
Shohachi Suzuki ◽  
Yoshihiro Yokoi ◽  
Shigeyasu Ota ◽  
Toshio Nakamura ◽  
...  
Keyword(s):  
Intrahepatic Cholangiocarcinoma ◽  
Inflammatory Pseudotumor ◽  
Hepatic Inflammatory Pseudotumor

Imaging Findings of Head and Neck Inflammatory Pseudotumor

2009 ◽  
Vol 193 (4) ◽  
pp. 1180-1186 ◽  
Author(s):  
Sung Bin Park ◽  
Jeong Hyun Lee ◽  
Young Cheol Weon
Keyword(s):  
Head And Neck ◽  
Inflammatory Pseudotumor ◽  
Imaging Findings

scholarly journals Accuracy of brush cytology in biliopancreatic strictures: a single-center cohort study

2021 ◽  
Vol 49 (2) ◽  
pp. 030006052098777
Author(s):  
Song-Ming Ding ◽  
Ai-Li Lu ◽  
Bing-Qian Xu ◽  
Shao-Hua Shi ◽  
Muhammad Ibrahim Alhadi Edoo ◽  
...  
Keyword(s):  
Duct Cell ◽  
Carbohydrate Antigen ◽  
Maximum Diameter ◽  
Biliary Duct ◽  
Brush Cytology ◽  
Tumor Biopsy ◽  
Bile Duct Wall ◽  
Negative Results ◽  
Brushing Cytology ◽  
Positive Results

Objective False positive and negative results are associated with biliary tract cell brushing cytology during endoscopic retrograde cholangiopancreatography (ERCP). The causes are uncertain. The purpose of this study was to evaluate the accuracy of diagnoses made via cell brushing in our center, and to explore the factors influencing diagnosis. Methods The clinical data of patients who underwent cell brushing at our center from January 2016 to August 2019 were retrospectively analyzed. These included age, gender, stricture location, thickness of the bile duct wall in the narrow segment, maximum diameter of the biliary duct above the stricture, number of cell brush smears, carbohydrate antigen 19-9, and carcinoembryonic antigen. Positive brush cytology results were compared with results of surgical histology or tumor biopsy as well as with the patient’s clinical course. Results Of the 48 patients who underwent cell brushing cytology, 27 (56.3%) had positive results. The sensitivity and specificity of biliary duct cell brushing was 79.4%, and 85.7%, respectively. None of the above-mentioned factors were associated with positive cytology brushing results. Conclusions Cell brushing cytology remains a reliable method for diagnosis of pancreaticobiliary malignancies.

scholarly journals IgG4-related hepatic inflammatory pseudotumor with sclerosing cholangitis: a case report and review of the literature

Cases Journal ◽  
2009 ◽  
Vol 2 (1) ◽  
pp. 7029 ◽  
Author(s):  
Itaru Naitoh ◽  
Takahiro Nakazawa ◽  
Hirotaka Ohara ◽  
Tomoaki Ando ◽  
Kazuki Hayashi ◽  
...  
Keyword(s):  
Case Report ◽  
Sclerosing Cholangitis ◽  
Inflammatory Pseudotumor ◽  
Review Of The Literature ◽  
Hepatic Inflammatory Pseudotumor

Cardiac metastasis of osteosarcoma

Open Medicine ◽  
2010 ◽  
Vol 5 (5) ◽  
pp. 551-555
Author(s):  
Hilal Sahin ◽  
Naim Ceylan ◽  
Selen Bayraktaroglu ◽  
Recep Savas
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Case Reports ◽  
Primary Tumour ◽  
Cardiac Metastasis ◽  
Imaging Findings ◽  
Cardiac Metastases ◽  
Enhanced Computed Tomography ◽  
Demographic Features

AbstractCardiac osteosarcoma metastasis is extremely rare and is documented in several case reports in the literature. The behaviour of osteosarcoma metastases is similar to the primary tumour. Thoracic non-enhanced computed tomography (CT) examination is beneficial in the detection of calcific cardiac metastases. In this case report, we describe a 29-year-old woman with cardiac osteosarcoma metastasis after 7 years of follow-up, compare the demographic features with previous cases and discuss the imaging findings.

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