A case of gastric signet-ring cell carcinoma with a long-term retrospective follow-up of 17 years

2021 ◽  
Author(s):  
Junichi Muraishi ◽  
Masaki Miyaoka ◽  
Kentaro Imamura ◽  
Kensei Ohtsu ◽  
Takao Kanemitsu ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Signet Ring ◽  
Ring Cell

Fundic Gland Polyp With Parietal Cell Vacuolation Mimicking Signet Ring Cell Carcinoma

2021 ◽  
pp. 106689692199418
Author(s):  
John D. Coyne ◽  
S. Thampy
Keyword(s):  
Proton Pump Inhibitor ◽  
Cell Carcinoma ◽  
Parietal Cell ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Fundic Gland ◽  
Fundic Gland Polyp ◽  
Signet Ring ◽  
Ring Cell

Pseudo-signet ring parietal cell vacuolation has been described as a mimic of invasive signet ring cell carcinoma. Moreover, signet ring cell carcinoma has been described in a fundic gland polyp. This case demonstrates parietal cell vacuolation in a fundic gland polyp in a patient on a long-term proton pump inhibitor.

scholarly journals Signet-ring Cell Carcinoma Derived from a Main Duct-type Intraductal Papillary Mucinous Neoplasm of the Pancreas: A Case Report with Long-term Follow-up

2018 ◽  
Vol 57 (8) ◽  
pp. 1093-1099 ◽  
Author(s):  
Toshitaka Sakai ◽  
Shinsuke Koshita ◽  
Kei Ito ◽  
Yoshihide Kanno ◽  
Takahisa Ogawa ◽  
...  
Keyword(s):  
Case Report ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Main Duct ◽  
Mucinous Neoplasm ◽  
Signet Ring ◽  
Long Term Follow Up ◽  
Ring Cell

scholarly journals Signet Ring Cell Carcinoma of the Appendix: A Case Report of Long-Term Survival

2019 ◽  
Vol 72 (1) ◽  
pp. 13-19
Author(s):  
Kenichi Ishizu ◽  
Toshio Nakamura ◽  
Kennnoki Kyo ◽  
Kazuya Okamoto ◽  
Takahiro Shimamura
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Term Survival ◽  
Long Term Survival ◽  
Signet Ring ◽  
Ring Cell

scholarly journals Long-Term Survival of a Patient with Invasive Signet-Ring Cell Carcinoma of the Urinary Bladder Managed by Combined S-1 and Cisplatin Adjuvant Chemotherapy

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Takashi Hamakawa ◽  
Yoshiyuki Kojima ◽  
Taku Naiki ◽  
Yasue Kubota ◽  
Takahiro Yasui ◽  
...  
Keyword(s):  
Adjuvant Chemotherapy ◽  
Urinary Bladder ◽  
Cell Carcinoma ◽  
Radical Cystectomy ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Term Survival ◽  
Signet Ring ◽  
Ring Cell

Primary signet-ring cell carcinoma of the urinary bladder is extremely rare and patient survival is very poor. The disease usually presents at advanced stages because the cancer progresses rapidly. The only option for effective treatment is radical cystectomy, and no effective chemotherapy has been established for this variant. We report a case of signet-ring cell carcinoma of the urinary bladder with a long-term survival of 90 months owing to radical cystectomy and combination adjuvant chemotherapy with S-1 and cisplatin. To our knowledge, this is the first report to demonstrate the long-term therapeutic activity of combination S-1 and cisplatin adjuvant chemotherapy against invasive signet-ring cell carcinoma of the urinary bladder.

scholarly journals A Case of Large-Intestine Signet Ring Cell Carcinoma with Prostatic Metastasis and Long-term 2-year Survival

2011 ◽  
Vol 44 (4) ◽  
pp. 482-489
Author(s):  
Tetsuji Yoshikawa ◽  
Katsutoshi Shouda ◽  
Yoshihiro Kitagawa ◽  
Hideyuki Chou ◽  
Hiroshi Ishii ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Large Intestine ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Signet Ring ◽  
Ring Cell

scholarly journals Signet Ring Cell Carcinoma of the Ampulla of Vater: A Rare Histopathological Variant

2018 ◽  
Vol 12 (1) ◽  
pp. 194-201 ◽  
Author(s):  
Guus W. de Klein ◽  
Joop van Baarlen ◽  
Leonie J. Mekenkamp ◽  
Mike S.L. Liem ◽  
Joost M. Klaase
Keyword(s):  
Cell Carcinoma ◽  
Immunohistochemical Staining ◽  
Mixed Type ◽  
Ampulla Of Vater ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Endoscopic Retrograde ◽  
Signet Ring ◽  
Ring Cell

Signet ring cell carcinoma (SRCC) of the ampulla of Vater is an extremely rare tumor. Our case describes a 45-year-old female presenting with jaundice and pruritus. Computed tomography, endoscopy, and endoscopic retrograde cholangiopancreatography showed a tumor of the ampulla of Vater without distant metastasis. Histological biopsy confirmed a malignant tumor with SRCC characteristics and immunohistochemical staining revealed a mixed type profile (both intestinal and pancreatobiliary characteristics). A pylorus-preserving pancreatoduodenectomy was performed and the patient recovered without complications. Pathology results concluded a pT2N0 ampullary SRCC. SRCC of the ampulla of Vater is known to be highly malignant. After 13 months of follow-up, our patient showed no signs of recurrence.

scholarly journals Primary Signet-Ring Cell Adenocarcinoma of the Urinary Bladder Treated with Partial Cystectomy: A Case Report and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Umesh Jayarajah ◽  
D. M. Hilary Fernando ◽  
Kasun Bandara Herath ◽  
M. V. Chandu de Silva ◽  
S. A. S. Goonewardena
Keyword(s):  
Cell Carcinoma ◽  
General Condition ◽  
Bladder Tumour ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Partial Cystectomy ◽  
Poor General Condition ◽  
Signet Ring ◽  
Ring Cell

Primary signet-ring cell carcinoma is a variant of adenocarcinoma which is extremely rare, associated with poor prognosis and generally found to be resistant to chemotherapy and radiotherapy. We report a case of primary signet-ring cell carcinoma of the bladder which was successfully treated with partial cystectomy. A 71-year-old female with a history of type 2 diabetes, hypertension, and ischaemic heart disease presented with painless haematuria for 2 months’ duration. The abdominal ultrasonography showed a localised polypoidal vesical growth arising from the bladder dome. Cystoscopy revealed an exophytic solid tumour in the anterior fundal wall. A deep transurethral resection of bladder tumour was done and histology revealed an adenocarcinoma composed of mucinous and signet-ring cell components. Later, considering the patient’s age and the poor general condition, a partial cystectomy was done. Follow-up cystoscopy and ultrasonography were done at 12 months and there was no evidence of tumour recurrence and the patient is currently symptom-free. Partial cystectomy may be considered in patients with localised tumour without evidence of metastasis and poor general condition. Regular cystoscopies and ultrasound imaging are necessary for follow-up and early identification of recurrences.

scholarly journals Primary Signet Ring Cell Carcinoma of the Prostate: A Rare Case Report

2018 ◽  
Vol 7 (8) ◽  
pp. 218 ◽  
Author(s):  
Alper Gök ◽  
Can Tuygun ◽  
Müge Akmansu ◽  
Ayşegül Aksakal Uslu ◽  
Ibrahim Güven Kartal ◽  
...  
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Prostate Adenocarcinoma ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Rare Form ◽  
Signet Ring ◽  
Rare Case Report ◽  
Ring Cell

Primary prostatic signet ring cell carcinoma is a rare form of cancer with a poor prognosis, which is generally treated with a traditional prostate adenocarcinoma therapy. This case report presents a 70-year-old diagnosed with primary prostatic signet ring cell carcinoma, treated with a combination of radiotherapy and hormone therapy and a 16 month survival without an evidence of the disease at follow up.

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