Prognostic significance of blood pressure response during vasodilator stress Rb-82 positron emission tomography myocardial perfusion imaging

2016 ◽  
Vol 24 (6) ◽  
pp. 1966-1975 ◽  
Author(s):  
Bradley Witbrodt ◽  
Abhinav Goyal ◽  
Anita A. Kelkar ◽  
Sharmila Dorbala ◽  
Benjamin J. W. Chow ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Positron Emission Tomography ◽  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Perfusion Imaging ◽  
Blood Pressure Response ◽  
Prognostic Significance ◽  
Emission Tomography ◽  
Vasodilator Stress ◽  
Positron Emission

Relative Prognostic Significance of Positron Emission Tomography Myocardial Perfusion Imaging Markers in Cardiomyopathy

2021 ◽  
Vol 14 (10) ◽  
Author(s):  
Merrill Thomas ◽  
Brett W. Sperry ◽  
Poghni Peri-Okonny ◽  
Ali O. Malik ◽  
A. Iain McGhie ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Perfusion Imaging ◽  
Prognostic Significance ◽  
Emission Tomography ◽  
Left Ventricular Ejection ◽  
Positron Emission ◽  
All Cause Mortality ◽  
Rubidium 82

Background: Rubidium-82 positron emission tomography myocardial perfusion imaging provides measurements of perfusion, myocardial blood flow and reserve (MBFR), and changes in left ventricular ejection fraction (LVEF) at rest and peak stress. Although all of these variables are known to provide prognostic information, they have not been well studied in patients with heart failure due to reduced LVEF. Methods: Between 2010 and 2016, 1255 consecutive unique patients with LVEF≤40% were included in this study who underwent rubidium-82 positron emission tomography myocardial perfusion imaging and did not have subsequent revascularization within 90 days. Perfusion assessment was scored semiquantitatively, and LVEF reserve (stress-rest LVEF) and global MBFR (stress/rest MBF) were quantified using automated software. Cox proportional hazards models adjusted for 14 clinical and 7 test characteristics were used to define the independent prognostic significance of MBFR on all-cause mortality. Results: Of 1255 patients followed for a mean of 3.2 years, 454 (36.2%) died. After adjusting for clinical variables, the magnitude of fixed and reversible perfusion defects was prognostic of death ( P =0.02 and 0.01, respectively), while the rest LVEF was not ( P =0.18). The addition of LVEF reserve did not add any incremental value, while the addition of MBFR revealed incremental prognostic value (hazard ratio per 0.1 unit decrease in MBFR=1.08 [95% CI, 1.05–1.11], P <0.001) with fixed and reversible defects becoming nonsignificant ( P =0.07 and 0.29, respectively). There was no interaction between MBFR and cause of cardiomyopathy (ischemic versus nonischemic). Conclusions: In patients with a known cardiomyopathy who did not require early revascularization, reduced MBFR as obtained by positron emission tomography myocardial perfusion imaging is associated with all-cause mortality while other positron emission tomography myocardial perfusion imaging measures were not.

Metastatic breast cancer diagnosed by rubidium-82 positron emission tomography myocardial perfusion imaging

2017 ◽  
Vol 25 (3) ◽  
pp. 1048-1050
Author(s):  
Ali Shafiq ◽  
Khawaja Afzal Ammar ◽  
Lynn Gilles ◽  
Nolan Machernis ◽  
Debra Mahlum ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Positron Emission Tomography ◽  
Metastatic Breast Cancer ◽  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Perfusion Imaging ◽  
Metastatic Breast ◽  
Emission Tomography ◽  
Positron Emission ◽  
Rubidium 82

Feasibility of exercise treadmill 13N-ammonia positron emission tomography myocardial perfusion imaging using an off-site cyclotron

2020 ◽  
Author(s):  
Daniel R. Harland ◽  
Patrycja Z. Galazka ◽  
Jerry Rasmussen ◽  
Debra Mahlum ◽  
Janelle Falk ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Perfusion Imaging ◽  
Emission Tomography ◽  
Positron Emission ◽  
Exercise Treadmill

Manganese-52m: A new myocardial perfusion imaging agent for positron emission tomography that does not require an on-site cyclotron

1982 ◽  
Vol 49 (4) ◽  
pp. 979
Author(s):  
Joann Urquhart ◽  
Randolph E. Patterson ◽  
Roger Aamodt ◽  
Edith Speir ◽  
Robert Kessler
Keyword(s):  
Positron Emission Tomography ◽  
Myocardial Perfusion Imaging ◽  
Myocardial Perfusion ◽  
Perfusion Imaging ◽  
Emission Tomography ◽  
Imaging Agent ◽  
Positron Emission
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