scholarly journals Combination of recombinant follicle stimulating hormone with human menopausal gonadotrophin or recombinant luteinizing hormone in a long gonadotrophin-releasing hormone agonist protocol: a retrospective study

2012 ◽  
Vol 11 (3) ◽  
pp. 129-133 ◽  
Author(s):  
Gottumukkala Achyuta Rama Raju ◽  
S. C. Teng ◽  
Prathigudupu Kavitha ◽  
Balabomma Kavitha Lakshmi ◽  
Cheemakurthi Ravikrishna
Keyword(s):  
Retrospective Study ◽  
Luteinizing Hormone ◽  
Follicle Stimulating Hormone ◽  
Releasing Hormone ◽  
Human Menopausal Gonadotrophin ◽  
Gonadotrophin Releasing Hormone ◽  
Recombinant Luteinizing Hormone ◽  
Stimulating Hormone

Differential pituitary response to GnRH in pregnant Booroola-Assaf and Assaf ewes

1992 ◽  
Vol 4 (2) ◽  
pp. 231 ◽  
Author(s):  
E Gootwine ◽  
A Bor ◽  
D Shalhevet ◽  
A Zenou ◽  
R Braw-Tal
Keyword(s):  
Luteinizing Hormone ◽  
Late Stage ◽  
Follicle Stimulating Hormone ◽  
Releasing Hormone ◽  
Gene Carriers ◽  
Basal Plasma ◽  
Gonadotrophin Releasing Hormone ◽  
Stimulating Hormone

Pituitary response to exogenous gonadotrophin-releasing hormone (GnRH) was examined at a late stage of pregnancy in 10 Booroola-Assaf ewes heterozygous at the FecB locus (FecBFec+) and in 11 Assaf ewes that were non-carriers (Fec+Fec+). Basal plasma luteinizing hormone (LH) and follicle stimulating hormone (FSH) concentrations were similar in the two genotypes. Administration of 100 micrograms of GnRH resulted in a significant increase (P < 0.05) in plasma LH and FSH concentrations in most of the ewes treated. Maximal responses were observed 105-135 min after GnRH treatment. Pituitary responses to GnRH were significantly lower (P < 0.05) in Booroola-Assaf than in Assaf ewes. The decreased pituitary responsiveness observed in FecB gene carriers compared with Fec+Fec+ ewes might be due to differences in the concentrations of ovarian or uterine hormones modulating the release of gonadotrophin. The results suggest that FecB-specific differences can be observed at the pituitary level.

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