Long-term quality of life after ileal pouch anal restorative proctocolectomy for ulcerative colitis

2012 ◽  
Vol 32 (1) ◽  
pp. 49-53 ◽  
Author(s):  
Babak Salehimarzijarani ◽  
Niloofar Yahyapour Jalaly ◽  
Zohreh Dadvar ◽  
Gholamreza Hemmasi ◽  
Maryam Ashrafi ◽  
...  
2019 ◽  
Vol 14 (6) ◽  
pp. 726-733 ◽  
Author(s):  
Pramodh Chandrasinghe ◽  
Michele Carvello ◽  
Karin Wasmann ◽  
Caterina Foppa ◽  
Pieter Tanis ◽  
...  

Abstract Background The transanal approach to ileal pouch-anal anastomosis [Ta-IPAA] provides better access to the lower pelvis with lower short-term morbidity in ulcerative colitis [UC]. The aim of this study was to assess the long-term functional outcomes after Ta-IPAA vs transabdominal IPAA [Abd-IPAA] in UC. Methods A multicentre cohort analysis was performed between March 2002 and September 2017. Patient characteristics, surgical details and postoperative outcomes were compared. CGQL [Cleveland global quality of life] score at 12 months with a functioning pouch was considered the primary end point. Results A total of 374 patients [100 Ta-IPAA vs 274 Abd-IPAA] were included. Ta-IPAA demonstrated a comparable overall quality of life [CGQL score] to Abd-IPAA [0.75 ± 0.11 vs 0.71 ± 0.14; respectively, p = 0.1]. Quality of life [7.71 ± 1.17 vs 7.30 ± 1.46; p = 0.04] and energy-level items [7.16 ± 1.52 vs 6.66 ± 1.68; p = 0.03] were significantly better after Ta-IPAA, while the quality of health item was comparable [7.68 ± 1.26 vs 7.64 ± 1.44; p = 0.96]. Analysis excluding anastomotic leaks did not change the overall CGQL scores. Stool frequencies [>10/24 h: 22% vs 21%; p = 1.0] and the rate of a single episode of major incontinence during the following 12-month period [27% vs 26%; p = 0.89] were similar. The differences in 30-day morbidity rates [33% vs 41%; p = 0.2] and anastomotic leak rates were not significant [6% vs 13%; p = 0.09]. Conclusions This study provides evidence of comparable long-term functional outcome and quality of life after Ta-IPAA and Abd-IPAA for UC.


2016 ◽  
Vol 70 (1) ◽  
pp. 38-44
Author(s):  
Marta Kostrejová ◽  
Martin Bortlík ◽  
Dana Ďuricová ◽  
Martin Kolář ◽  
Richard Sequens ◽  
...  

2018 ◽  
Vol 23 (3) ◽  
pp. 571-579 ◽  
Author(s):  
Olga A. Lavryk ◽  
Luca Stocchi ◽  
Tracy L. Hull ◽  
Emre Gorgun ◽  
Sherief Shawki ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Ola Røkke ◽  
Knut Iversen ◽  
Torill Olsen ◽  
Sølvi-Mai Ristesund ◽  
Geir Egil Eide ◽  
...  

Aims. Evaluate the early and long term surgical and functional results of the ileal pouch-reservoir (IPAA) in patients with intractable ulcerative colitis. Material and Methods. Followup of 134 consecutive patients with W-or J-ileal pouch by diseases-specific and general health (SF-36) questionnaire. In the first 44 patients, early and late followup was performed. Results. Followup was performed 7.4 years (0.5–17 years) after construction of W () and J () ileal pouch, which had similar results. There were 14.9% early and 43.6% late complications with 12.7% early and 19.5% late reoperations. Protecting loop-ileostomy used in 54 patients (43.9%), did not protect against complications. Thirteen reservoirs (9.8%) were resected () or deactivated () due to functional failure. Operation time, postoperative complications and pouchitis were determinators for reservoir failure and reduced quality of life. The functional results at followup of 44 patients at 2.5 years (0.8–6.7 years) and 11.5 years (8.2–19.2 years) were remarkably similar. Conclusions. IPAA is a good option for most patients when medication fails. 10% experience failure with inferior quality of life. Protective stoma will not reduce failure rates. After an initial time period, reservoir function will not change over time.


2007 ◽  
Vol 13 (10) ◽  
pp. 1228-1235 ◽  
Author(s):  
Mirjam Tariverdian ◽  
Christine Leowardi ◽  
Ulf Hinz ◽  
Thilo Welsch ◽  
Jan Schmidt ◽  
...  

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