scholarly journals Fibrous Dysplasia Mimicking Bone Metastasis on Both Bone Scintigraphy and 18F-FDG PET-CT: Diagnostic Dilemma in a Patient with Breast Cancer

2012 ◽  
Vol 46 (4) ◽  
pp. 318-319 ◽  
Author(s):  
Sudhir Suman KC ◽  
Punit Sharma ◽  
Harmandeep Singh ◽  
Chandrasekhar Bal ◽  
Rakesh Kumar
2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Kusai M. Al-Muqbel

Objective. To determine the value of 18F-FDG PET/CT in detection of bone marrow (BM) metastasis in breast cancer which is considered an early stage of bone metastasis. Patients and Methods. Retrospectively, breast cancer patients with bone metastasis were included. BM metastasis was considered if the lesion was PET positive/CT occult while bone metastasis was considered if the lesion was PET positive/ CT positive. BM metastases were observed sequentially on F18-FDG PET/CT. Results. We included 35 patients. Eighteen patients (51%) had BM metastases in addition to other bone metastases. BM metastases comprised 24% of all lesions. Posttreatment scan was performed on 26/35 patients. Twenty-three percent of BM metastases had resolved completely without causing bone destruction after treatment. Sixty-five percent of BM metastases had converted into bone metastases after treatment. Twelve percent of BM metastases had persisted after treatment. Conclusion. This retrospective study showed clinically by 18F-FDG PET/CT imaging that BM metastasis is an early stage of bone metastasis in breast cancer. Interestingly, 18F-FDG-PET/CT showed that early eradication of individual BM metastasis by systemic treatment precluded development of bone metastasis. However, more research is needed to study the impact of an early diagnosis of BM metastases on treatment outcome.


2011 ◽  
Vol 52 (7) ◽  
pp. 779-787 ◽  
Author(s):  
Xu Cheng ◽  
Yongjun Li ◽  
Zhaoqiang Xu ◽  
Lihua Bao ◽  
Dianfu Li ◽  
...  

2014 ◽  
Vol 28 (5) ◽  
pp. 411-416 ◽  
Author(s):  
Zhongyi Yang ◽  
Yongping Zhang ◽  
Wei Shi ◽  
Beiling Zhu ◽  
Silong Hu ◽  
...  

Diagnostics ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 682
Author(s):  
Wei-Liang Hung ◽  
Hung-Yen Chan ◽  
Ni-Chun Kuo ◽  
Hung-Pin Chan

A 51-year-old woman who had lung adenocarcinoma was found to have a high uptake area over the right femoral neck by means of bone scintigraphy, suggesting a suspicious bony metastasis. 18F-FDG PET/CT was arranged, and showed an FDG-avid lesion in the same region. However, after augmented CT, a well-defined ground-glass lesion with circular calcification was found, which is the favored benign lesion of fibrous dysplasia. The following imaging of bone scintigraphy and 18F-FDG PET/CT presented no apparent change. This case demonstrates that the treatment scheme should not be solely guided by abnormalities in scintigraphy. Additional imaging is recommended for accurate staging or development of an appropriate treatment plan.


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