National Institutes of Health (NIH) Executive Meeting Summary: Developing Medical Countermeasures to Rescue Opioid-Induced Respiratory Depression (a Trans-Agency Scientific Meeting)—August 6/7, 2019

Study of the human microbiota has been a centuries-long endeavor, but since the inception of the National Institutes of Health (NIH) Human Microbiome Project in 2007, research has greatly expanded, including the space involving radiation injury. As acute radiation syndrome (ARS) is multisystemic, the microbiome niches across all areas of the body may be affected. This review highlights advances in radiation research examining the effect of irradiation on the microbiome and its potential use as a target for medical countermeasures or biodosimetry approaches, or as a medical countermeasure itself. The authors also address animal model considerations for designing studies, and the potential to use the microbiome as a biomarker to assess radiation exposure and predict outcome. Recent research has shown that the microbiome holds enormous potential for mitigation of radiation injury, in the context of both radiotherapy and radiological/nuclear public health emergencies. Gaps still exist, but the field is moving forward with much promise.

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Abstracts of Presentations from the 2020 Trans-Agency Scientific Meeting on Developing Medical Countermeasures to Treat the Acute and Chronic Effects of Ocular Chemical Toxicity, 25–26 February, Bethesda, Maryland

Toxicology Letters ◽

10.1016/j.toxlet.2020.05.026 ◽

2020 ◽

Vol 331 ◽

pp. 1-3 ◽

Cited By ~ 1

Author(s):

David T. Yeung ◽

Houmam Araj ◽

Patrick M. McNutt

Keyword(s):

Scientific Meeting ◽

Chemical Toxicity ◽

Chronic Effects ◽

Acute And Chronic Effects ◽

Medical Countermeasures

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The 1-MeV Electron Microscope Installation at the University of Colorado

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100070485 ◽

1973 ◽

Vol 31 ◽

pp. 8-9 ◽

Cited By ~ 1

Author(s):

Mircea Fotino

Keyword(s):

Electron Microscopy ◽

Developmental Biology ◽

Transmission Electron Microscopy ◽

Electron Microscope ◽

National Institutes Of Health ◽

Experimental Program ◽

University Of Colorado ◽

Transmission Electron ◽

The University ◽

Research Resources

A new 1-MeV transmission electron microscope (Model JEM-1000) was installed at the Department of Molecular, Cellular and Developmental Biology of the University of Colorado in Boulder during the summer and fall of 1972 under the sponsorship of the Division of Research Resources of the National Institutes of Health. The installation was completed in October, 1972. It is installed primarily for the study of biological materials without many of the limitations hitherto unavoidable in standard transmission electron microscopy. Only the technical characteristics of the installation are briefly reviewed here. A more detailed discussion of the experimental program under way is being published elsewhere.

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