Clinicopathological and prognostic significance of hypoxia-inducible factor-1α in esophageal squamous cell carcinoma: a meta-analysis

Tumor Biology ◽  
2014 ◽  
Vol 35 (5) ◽  
pp. 4401-4409 ◽  
Author(s):  
Wei Ping ◽  
Wei Sun ◽  
Yukun Zu ◽  
Wenshu Chen ◽  
Xiangning Fu
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Meta Analysis ◽  
Hypoxia Inducible Factor ◽  
Prognostic Significance ◽  
Hypoxia Inducible Factor 1Α

Expression of p53 Protein in Esophageal Squamous Cell Carcinoma: Relation to Hypoxia-Inducible Factor-1α, Angiogenesis and Apoptosis

Pathobiology ◽  
2005 ◽  
Vol 72 (4) ◽  
pp. 179-185 ◽  
Author(s):  
Shigeru Kimura ◽  
Yasuhiko Kitadai ◽  
Toshio Kuwai ◽  
Shinji Tanaka ◽  
Jun Hihara ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
P53 Protein ◽  
Hypoxia Inducible Factor ◽  
Hypoxia Inducible Factor 1Α

Prognostic significance of C-MYC dysregulation in esophageal squamous cell carcinoma: a meta-analysis

2020 ◽  
Vol 14 (7) ◽  
pp. 599-609
Author(s):  
Xuejiao Shi ◽  
Renhua Zhou ◽  
Leizhen Zheng ◽  
Mawei Jiang
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Web Of Science ◽  
Meta Analysis ◽  
Prognostic Significance ◽  
Cochrane Library ◽  
Poor Overall Survival ◽  
The Cochrane Library

Aim: The clinicopathological and prognostic significance of C-MYC dysregulation (amplification or overexpression) in esophageal squamous cell carcinoma (ESCC) remains controversial. Therefore, we performed this meta-analysis to elucidate this relationship. Materials & methods: Available studies were retrieved from PubMed, Web of Science, EMBASE and the Cochrane Library, and ten studies with a total of 1432 patients were included in this meta-analysis. Results: Pooled results showed that C-MYC dysregulation was significantly associated with poor overall survival (hazard ratio: 1.405 [95% CI: 1.170–1.639]; p < 0.001) and lymph node metastasis (odds ratio: 1.798 [95% CI: 1.125–2.873]; p = 0.014). Subgroup analysis confirmed the results and more prominent predictive effects were observed in the C-MYC amplification group. Conclusion: C-MYC dysregulation is a promising biomarker for ESCC prognosis.

Prognostic significance of overexpressed p16INK4A in esophageal squamous cell carcinoma: a meta-analysis

2016 ◽  
Vol 10 (5) ◽  
pp. 537-546 ◽  
Author(s):  
Lianghai Wang ◽  
Jing Li ◽  
Xiaodan Yu ◽  
Zhiyu Zhang ◽  
Lijuan Pang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Meta Analysis ◽  
Prognostic Significance
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