Combination of zoledronic acid and serine/threonine phosphatase inhibitors induces synergistic cytotoxicity and apoptosis in human breast cancer cells via inhibition of PI3K/Akt pathway

Human Breast ◽

Phosphatase Inhibitors ◽

Synergistic Cytotoxicity

99P Zoledronic Acid in Combination with Serine/Threonine Phosphatase Inhibitors Induces Cytotoxicity and Apoptosis in Human Breast Cancer Cells via Decreasing the Activities of Pp1 and Pp2A

Annals of Oncology ◽

10.1016/s0923-7534(19)65743-1 ◽

2012 ◽

Vol 23 ◽

pp. ii42

Author(s):

Z.G. Surmeli ◽

P. Gursoy ◽

B. Cakar ◽

K. Asli ◽

H. Atmaca ◽

...

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Human Breast ◽

Phosphatase Inhibitors

Intracellular Src Family Kinases Mediate PI3K-Akt Pathway Activation and Resistance to Lapatinib in HER2-Overexpressing Human Breast Cancer Cells.

10.1158/0008-5472.sabcs-09-707 ◽

2009 ◽

Author(s):

B. Rexer ◽

A. Chakrabarty ◽

C. Rinehart ◽

S. Hill ◽

M. Olivares ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Src Family Kinases ◽

Akt Pathway ◽

Human Breast ◽

Pathway Activation

Lower concentrations of curcumin inhibit Her2-Akt pathway components in human breast cancer cells, and other dietary botanicals potentiate this and lapatinib inhibition

Nutrition Research ◽

10.1016/j.nutres.2020.05.007 ◽

2020 ◽

Vol 78 ◽

pp. 93-104

Author(s):

Abhinav R Saxena ◽

Zoran Ilic ◽

Veda Sripada ◽

Dana R. Crawford

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Akt Pathway ◽

Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells

Biochemical Pharmacology ◽

10.1016/j.bcp.2009.10.003 ◽

2010 ◽

Vol 79 (5) ◽

pp. 777-783 ◽

Cited By ~ 36

Author(s):

Johanna Räikkönen ◽

Hannu Mönkkönen ◽

Seppo Auriola ◽

Jukka Mönkkönen

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Mevalonate Pathway ◽

Human Breast ◽

Isopentenyl Pyrophosphate

Synergistic cytotoxicity between tamoxifen and the plant toxin persin in human breast cancer cells is dependent on Bim expression and mediated by modulation of ceramide metabolism

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-07-0374 ◽

2007 ◽

Vol 6 (10) ◽

pp. 2777-2785 ◽

Cited By ~ 22

Author(s):

C. G. Roberts ◽

E. Gurisik ◽

T. J. Biden ◽

R. L. Sutherland ◽

A. J. Butt

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Human Breast ◽

Plant Toxin ◽

Synergistic Cytotoxicity

IL-12 induces autophagy in human breast cancer cells through AMPK and the PI3K/Akt pathway

Molecular Medicine Reports ◽

10.3892/mmr.2017.7114 ◽

2017 ◽

Vol 16 (4) ◽

pp. 4113-4118 ◽

Cited By ~ 15

Author(s):

Yan Lin ◽

Wenbin Kuang ◽

Bitao Wu ◽

Changli Xie ◽

Cuiyin Liu ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Akt Pathway ◽

Early Detection of Bone Metastases in a Murine Model Using Fluorescent Human Breast Cancer Cells: Application to the Use of the Bisphosphonate Zoledronic Acid in the Treatment of Osteolytic Lesions

Journal of Bone and Mineral Research ◽

10.1359/jbmr.2001.16.11.2027 ◽

2001 ◽

Vol 16 (11) ◽

pp. 2027-2034 ◽

Cited By ~ 126

Author(s):

Olivier Peyruchaud ◽

Bent Winding ◽

Isabelle Pécheur ◽

Claire-Marie Serre ◽

Pierre Delmas ◽

...

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Early Detection ◽

Cancer Cells ◽

Murine Model ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Human Breast ◽

Osteolytic Lesions

Author Correction: Synergistic suppression of human breast cancer cells by combination of plumbagin and zoledronic acid in vitro

Acta Pharmacologica Sinica ◽

10.1038/s41401-019-0232-x ◽

2019 ◽

Vol 40 (8) ◽

pp. 1127-1128

Author(s):

Han Qiao ◽

Ting-yu Wang ◽

Wei Yan ◽

An Qin ◽

Qi-ming Fan ◽

...

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Inhibition of the phosphatidylinositol 3-kinase/Akt pathway sensitizes MDA-MB468 human breast cancer cells to cerulenin-induced apoptosis

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-05-0049 ◽

2006 ◽

Vol 5 (3) ◽

pp. 494-501 ◽

Cited By ~ 40

Author(s):

Xuesong Liu ◽

Yan Shi ◽

Vincent L. Giranda ◽

Yan Luo

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Akt Pathway ◽

Human Breast ◽

Phosphatidylinositol 3 Kinase ◽

Induced Apoptosis ◽

Phosphatidylinositol 3

Downregulation of cPLA2γ expression inhibits EGF-induced chemotaxis of human breast cancer cells through Akt pathway

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2011.05.035 ◽

2011 ◽

Vol 409 (3) ◽

pp. 506-512 ◽

Cited By ~ 3

Author(s):

Gang Tian ◽

Xueqian Wang ◽

Fei Zhang ◽

Hua Geng ◽

Wei Hou ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Akt Pathway ◽