Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells

Biochemical Pharmacology ◽

10.1016/j.bcp.2009.10.003 ◽

2010 ◽

Vol 79 (5) ◽

pp. 777-783 ◽

Author(s):

Johanna Räikkönen ◽

Hannu Mönkkönen ◽

Seppo Auriola ◽

Jukka Mönkkönen

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Mevalonate Pathway ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Isopentenyl Pyrophosphate

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Synergistic anti-tumour effects on human breast cancer cells by mevalonate pathway inhibitors atorvastatin and zoledronic acid

Bone Abstracts ◽

10.1530/boneabs.1.pp145 ◽

2013 ◽

Author(s):

Andy Gobel ◽

Stefanie Thiele ◽

Martina Rauner ◽

Lorenz C Hofbauer ◽

Tilman D Rachner

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Mevalonate Pathway ◽

Human Breast Cancer Cells ◽

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Combined inhibition of the mevalonate pathway with statins and zoledronic acid potentiates their anti-tumor effects in human breast cancer cells

Cancer Letters ◽

10.1016/j.canlet.2016.03.004 ◽

2016 ◽

Vol 375 (1) ◽

pp. 162-171 ◽

Author(s):

Andy Göbel ◽

Stefanie Thiele ◽

Andrew J. Browne ◽

Martina Rauner ◽

Valentina M. Zinna ◽

...

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Mevalonate Pathway ◽

Human Breast Cancer Cells ◽

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Induction of mitochondria-dependent apoptosis through the inhibition of mevalonate pathway in human breast cancer cells by YM529, a new third generation bisphosphonate

Cancer Letters ◽

10.1016/j.canlet.2007.01.008 ◽

2007 ◽

Vol 253 (1) ◽

pp. 89-96 ◽

Author(s):

Hiroo Nakajima ◽

Junji Magae ◽

Mie Tsuruga ◽

Koichi Sakaguchi ◽

Ikuya Fujiwara ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Mevalonate Pathway ◽

Third Generation ◽

Human Breast Cancer Cells ◽

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Combination of zoledronic acid and serine/threonine phosphatase inhibitors induces synergistic cytotoxicity and apoptosis in human breast cancer cells via inhibition of PI3K/Akt pathway

Tumor Biology ◽

10.1007/s13277-015-3265-x ◽

2015 ◽

Vol 37 (3) ◽

pp. 3665-3673

Author(s):

Zeki Surmeli ◽

Pinar Gursoy ◽

Atike Pinar Erdogan ◽

Emir Bozkurt ◽

Harika Atmaca ◽

...

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Akt Pathway ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Phosphatase Inhibitors ◽

Synergistic Cytotoxicity

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Simvastatin inhibition of mevalonate pathway induces apoptosis in human breast cancer cells via activation of JNK/CHOP/DR5 signaling pathway

Cancer Letters ◽

10.1016/j.canlet.2012.08.031 ◽

2013 ◽

Vol 329 (1) ◽

pp. 9-16 ◽

Author(s):

Archana Gopalan ◽

Weiping Yu ◽

Bob G. Sanders ◽

Kimberly Kline

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Signaling Pathway ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Mevalonate Pathway ◽

Human Breast Cancer Cells ◽

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Early Detection of Bone Metastases in a Murine Model Using Fluorescent Human Breast Cancer Cells: Application to the Use of the Bisphosphonate Zoledronic Acid in the Treatment of Osteolytic Lesions

Journal of Bone and Mineral Research ◽

10.1359/jbmr.2001.16.11.2027 ◽

2001 ◽

Vol 16 (11) ◽

pp. 2027-2034 ◽

Author(s):

Olivier Peyruchaud ◽

Bent Winding ◽

Isabelle Pécheur ◽

Claire-Marie Serre ◽

Pierre Delmas ◽

...

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Early Detection ◽

Cancer Cells ◽

Murine Model ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Osteolytic Lesions

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Author Correction: Synergistic suppression of human breast cancer cells by combination of plumbagin and zoledronic acid in vitro

Acta Pharmacologica Sinica ◽

10.1038/s41401-019-0232-x ◽

2019 ◽

Vol 40 (8) ◽

pp. 1127-1128

Author(s):

Han Qiao ◽

Ting-yu Wang ◽

Wei Yan ◽

An Qin ◽

Qi-ming Fan ◽

...

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Human Breast Cancer Cells ◽

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Preventive Effects of Zoledronic Acid on Bone Metastasis in Mice Injected with Human Breast Cancer Cells

Journal of Korean Medical Science ◽

10.3346/jkms.2011.26.12.1569 ◽

2011 ◽

Vol 26 (12) ◽

pp. 1569 ◽

Author(s):

Joon Jeong ◽

Kyung Sun Lee ◽

Yang-Kyu Choi ◽

Young Ju Oh ◽

Hy-De Lee

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Bone Metastasis ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Preventive Effects

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99P Zoledronic Acid in Combination with Serine/Threonine Phosphatase Inhibitors Induces Cytotoxicity and Apoptosis in Human Breast Cancer Cells via Decreasing the Activities of Pp1 and Pp2A

Annals of Oncology ◽

10.1016/s0923-7534(19)65743-1 ◽

2012 ◽

Vol 23 ◽

pp. ii42

Author(s):

Z.G. Surmeli ◽

P. Gursoy ◽

B. Cakar ◽

K. Asli ◽

H. Atmaca ◽

...

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Phosphatase Inhibitors

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Synergistic suppression of human breast cancer cells by combination of plumbagin and zoledronic acid In vitro

Acta Pharmacologica Sinica ◽

10.1038/aps.2015.42 ◽

2015 ◽

Vol 36 (9) ◽

pp. 1085-1098 ◽

Author(s):

Han Qiao ◽

Ting-yu Wang ◽

Wei Yan ◽

An Qin ◽

Qi-ming Fan ◽

...

Keyword(s):

Breast Cancer ◽

Zoledronic Acid ◽

Cancer Cells ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Human Breast Cancer Cells ◽

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