Bangabandhu Sheikh Mujib Medical University Journal
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Published By Bangladesh Journals Online

2224-7750, 2074-2908

Author(s):  
Mohammed Mirazur Rahman ◽  
AKM Mosharraf Hossain ◽  
Mohammed Atiqur Rahman ◽  
Shamim Ahmed ◽  
Rajashish Chakrabortty ◽  
...  

This cross-sectional observational study was conducted among COVID-19 patients at Department of Respiratory Medicine, Bangabandhu Sheikh Mujib Medical University from July 2020 to December 2020. During follow-up around three months (90.62±2.21days) after the onset of the first COVID-19 symptoms, 500 patients were taken as the study sample. Our study aimed to assess the persistent symptoms in patients who were discharged from the hospital after recovery from COVID-19. This study has shown that persistent respiratory symptoms were common after COVID-19 and the majority of patients were symptom-free three months after COVID-19 onset. BSMMU J 2021; 14 (COVID -19 Supplement): 19-21


Author(s):  
Mohammad Shamsul Ahsan ◽  
Suman Ahmed ◽  
Rubaiya Khan ◽  
Md Mahbubul Hasan ◽  
Ananya Kar ◽  
...  

This study aimed to estimate the prevalence of depression, anxiety, post-traumatic stress disorder, and insomnia symptoms among frontline health workers during the corona virus disease 19 (COVID-19) pandemic in Bangladesh and to compare these between medical and allied health workers. We conducted a cross-sectional survey between June and August 2020. A total of 479 health care professionals participated in the study. Anxiety and depression were measured using Patient Health Questionnaire-4 (PHQ-4), post-traumatic stress disorder (PTSD) was measured by primary care post-traumatic stress disorder score (PC-PTSD score), and insomnia was measured by Insomnia Severity Index (ISI). We performed logistic regression to assess risk factors associated with psychological symptoms. Overall, prevalence of anxiety, depression, PTSD and insomnia symptoms were 17.6%, 15.5%, 7.6% and 5.9%, respectively. Compared to allied health workers, doctors had significantly higher prevalence of symptoms of anxiety: doctor versus allied health care worker; 21.1% vs 06%, (OR= 4.19; 95% CI= 1.88-9.35; p <0.001); depression: 18% vs 6.8%, (OR= 2.99; 95% CI= 1.40-6.42; p 0.005); PTSD: 9.4% vs 1.7%, (OR= 5.96; 95% CI= 1.41-25.11; p 0.015) and insomnia: 7.4% vs 0.9%, (OR= 9.22; 95% CI= 1.24-68.4; p 0.03),respectively. The logistic regression analysis showed pre-existing medical illness as a predictor of anxiety (OR= 2.85; 95% CI= 1.71-4.76; p <0.001) and depressive symptoms (OR= 2.29; 95% CI= 1.39-3.77; p 0.001). Working more than 6(six) weeks in COVID-19 dedicated hospitals was significantly associated with PSTD symptoms (OR= 2.83; 95% CI= 1.35-5.93; p 0.006) and insomnia (OR= 2.63; 95% CI= 1.15-6.02; p 0.022). Our study demonstrated a high prevalence of symptoms of depression, anxiety, PTSD, and insomnia among Bangladeshi frontline health workers during the COVID-19 pandemic. BSMMU J 2021; 14 (COVID -19 Supplement): 22-29


Author(s):  
Moshiur Rahman Khasru ◽  
Fariha Haseen ◽  
Md Moniruzzaman Khan ◽  
Radia Naz ◽  
Tangila Marzen ◽  
...  

COVID-19 pandemic is now a great headache for the world population. Respiratory symptoms are the main presentation of COVID-19. However, musculoskeletal pain, headache, loss of taste and smell sense, and neurological manifestations may occur. Identification of patterns of musculoskeletal pain, fatigue and physical health status in COVID-19 is crucial. In this cross sectional study, a total 380 individuals with COVID-19 were recruited from the population following selection criteria. Pain varied widely in hip, neck, leg and calf muscles, back and spine, shoulder, arms and hand, and other parts of the body among the respondents. Inconstant, among respondents of younger age group (aged ≤50 year), 37.59% had moderate pain, 6.77% had severe pain, 13.91% had mild pain, and 41.17% had no pain. On the other hand, among older respondents (aged >50 year) 47.37% had moderate pain, 25.44% had severe pain, 13.15% had mild pain, and 14.03% had no pain. The differences between two groups was statistically significant (p<0.05). However, there was no difference in frequency of pain between males and females. Those respondents who had pain was reported having physical health worse than the average compared to that of those who had no pain. BSMMU J 2021; 14 (COVID -19 Supplement): 1-7


Author(s):  
Shishir Sikto Sarker ◽  
SM Ali Hasan ◽  
Md Sarower Islam ◽  
Nimai Das ◽  
Kazi Monisur Rahman ◽  
...  

Corona Virus Disease (COVID-19), a threat to global public health, caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) has now spread to more than two hundred countries in the world. This ongoing pandemic has already been exhausted our health care systems. So determining or predicting the need of healthcare resources has now become a number one priority and the length of hospitalization is a scale which represents the function of the health system of countries. Our objectives were to see the length of hospital stay of COVID-19 patients and its relationship with liver function abnormalities. This obser- vational cross-sectional study was carried out in the COVID-19 inpatient department of BSMMU on 96 patients who are RT-PCR positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Liver function abnormalities (ALT, AST, ALP, PT, serum biliru- bin and serum albumin) were recorded precisely. Length of hospital stay was documented. Occurrence of liver function abnormalities and their relation with length of hospital stay were assessed statistically. Total 96 patients were included. Mean hospital stay was found to be 14.0±6.2 with range from 5.0 to 33 days. Total 49(51.0%) patients required hospital staying ≤14 days and 47(49%) patients were found hospital stay > 14 days. Mean length of hospital stay in case of mild COVID-19 patients was 6.76±1.12 days, in case of moderate Covid-19 patients was 12.22±1.91 days and in severe group it was 19.18±4.81 days. The mean length of hospital stay was statistically significant with raised ALT (18.9±6.2), raised AST(18.9±5.9) and low serum albumin (19.4±7.1) group (p<0.05). No significant association was found between mean length of hospital stay and raised ALP, PT and S. bilirubin group. This study showed that length of hospital stay were significantly higher among severe COVID-19 patients and among liver function abnormalities raised ALT, raised AST and low serum albumin were associated with significant longer hospital stay. Assessing the length of hospital stay is helpful in under- standing and predicting hospital bed demand and optimizing the use of healthcare resources. BSMMU J 2021; 14 (COVID -19 Supplement): 8-12


Author(s):  
Ashraful Hoque ◽  
Talukder Mohammad Al Amin

From the beginning of corona virus disease 19(COVID-19) pandemic, there has been concern how to protect vulnerable group like pregnant women from severe acute respiratory syndrome corona virus 2(SARS-CoV-2). Historically, pregnant women experiences increased mortality during any pandemic situation. Pregnant women show almost the similar clinical features as that of non-pregnant adults with COVID-19 infection. Different systematic reviews have begun to focus light on pregnancy outcomes in COVID-19 patients, but knowledge is very limited and still the basis is case series and individual experiences. Apart from the scientifically proven therapeutic options used in COVID-19 such as steroid, low molecular weight heparin, the role of convalescent plasma therapy (CPT) has never been evaluated. We present a case of a pregnant woman of 32 weeks of conception, treated with CPT with favourable outcome in a private hospital of Dhaka, Bangladesh. BSMMU J 2021; 14 (COVID -19 Supplement): 64-66


Author(s):  
Abhishek Bhadra ◽  
Md Sharfuddin Ahmed ◽  
Mohammed Atiqur Rahman ◽  
Samprity Islam

Abstract not available BSMMU J 2021; 14 (COVID -19 Supplement): 51-56


Author(s):  
Md Sharfuddin Ahmed

Abstract not available BSMMU J 2021; 14 (COVID -19 Supplement): i


Author(s):  
Md Nazmul Hasan ◽  
Chowdhury Adnan Sami ◽  
Md Rasul Amin ◽  
Abed Hussain Khan ◽  
Sunil Kumar Biswas

Autoimmune hemolytic anaemia (AIHA) can be caused by many diseases like connective tissue disease, lymphoproliferative disorder, certain infections and various medications. The coronavirus disease 19(COVID-19) can cause an increased risk of thrombosis. But, the association of AIHA with COVID-19 is not well understood. Here, in this case report a 45-year-old man who presented with fever, cough, anaemia and splenomegaly. On further investigation, he was confirmed as severe COVID-19 case with AIHA. Subsequently he was managed with prednisolone with good results. BSMMU J 2021; 14 (COVID -19 Supplement): 57-59


Author(s):  
Rawnak Jahan ◽  
Mohammed Atiqur Rahman ◽  
AKM Mosharraf Hossain ◽  
Shamim Ahmed ◽  
Rajashish Chakrabortty ◽  
...  

COVID-19 is a highly infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). Recently COVID -19 radiological literature focuses primarily on CT scan findings which are more sensitive (about 97%) and specific than chest x-ray. But it has to be remembered that performing CT scan is not easy during this pandemic situation. So, the aim of the study was to analyze the chest x-ray severity scoring system and its association with outcome in a young adult patient with COVID-19. This cross-sectional study was carried out from September 15 to December 31 2020 in the COVID unit of BSMMU and it included 100 RT-PCR positive COVID-19 patients according to selection criteria. Chest x-ray postero-anterior view was done in the radiology department of BSMMU. Each patient’s chest x-ray was examined by a radiologist and a pulmonologist with experience of 10 years. Radiological scoring was done by using a scoring system. All patients were followed after 20 days from the first presentation to see the outcome. Out of 100 patients, 73 patients (73%) needed hospital admission, 33(33%) patients were hospitalized but did not developed sepsis, 29 (29%) patient developed sepsis, 10(10%) patient needed ICU support among them 2 patients got intubation. 1(1%) patient was dead. Radiological score ≥ 4 was associated with increased risk of hospitalization. (Area under curve = 0.956). Score ≥ 5 was associated with increased risk of sepsis; score ≥7 was associated with increased risk of ICU admission. (p-value<0.001). BSMMU J 2021; 14 (COVID -19 Supplement): 30-35


Author(s):  
SM Rashed Ul Islam ◽  
Tahmina Akther ◽  
Sharmin Sultana ◽  
Paroma Deb ◽  
Asish Kumar Ghosh ◽  
...  

The health care systems in resource limited countries are facing major challenges in dealing with Coronavirus disease (COVID-19). In Bangladesh, a steady increase in the number of COVID-19 cases since its first report on March 8, 2020, has led to an increased demand for COVID-19 detection facilities throughout the country. The detection of severe acute respiratory syndrome (SARS-CoV-2), the causative organism of COVID-19 and a highly infectious group 3(three) organism, requires a high biocontainment laboratory with a certain standard prerequisite infrastructure. This study describes the necessary steps for establishing and running a COVID-19 laboratory under resource constraint settings. Our experience indicates that, with collaborative efforts, funding, and technical support from locally available expertise, it is feasible to set up an optimally functional biocontainment facility with an acceptable quality performance despite several short comings. BSMMU J 2021; 14 (COVID -19 Supplement): 45-50


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