A Thickened Amino-Acid Formula in Infants with Cow’s Milk Allergy Failing to Respond to Protein Hydrolysate Formulas: A Randomized Double-Blind Trial

2014 ◽  
Vol 16 (6) ◽  
pp. 513-522 ◽  
Author(s):  
Christophe Dupont ◽  
Nicolas Kalach ◽  
Pascale Soulaines ◽  
Elena Bradatan ◽  
Alain Lachaux ◽  
...  
2008 ◽  
Vol 121 (2) ◽  
pp. S244-S244
Author(s):  
M MORISSET ◽  
P SOULAINES ◽  
C AUBERTJACQUIN ◽  
F CODREANU ◽  
N MAAMRI ◽  
...  

2016 ◽  
Vol 19 (12) ◽  
pp. 1207-1214 ◽  
Author(s):  
Mauro Batista de Morais ◽  
José Vicente Spolidoro ◽  
Mário César Vieira ◽  
Ary Lopes Cardoso ◽  
Otavio Clark ◽  
...  

2021 ◽  
Vol 47 (1) ◽  
Author(s):  
Rita Nocerino ◽  
Carmen Di Scala ◽  
Serena Coppola ◽  
Veronica Giglio ◽  
Laura Carucci ◽  
...  

Abstract Background Amino acid-based formula (AAF) is a relevant dietary strategy for paediatric patients affected by cow’s milk allergy (CMA). The present study was designed to evaluate the hypoallergenicity of a new AAF in children with immunoglobulin (Ig)E-mediated CMA. Methods According to the criteria provided by the American Academy of Pediatrics Subcommittee on Nutrition and Allergic Diseases, we designed a prospective trial in CMA children (aged 1–36 months) aimed to demonstrate the hypoallergenicity of the new AAF in 90% of subjects with 95% confidence during the double-blind, placebo-controlled challenge (DBPCFC). A skin prick test (SPT) with the new AAF was also performed. Results Twenty-nine children [all Caucasian, 55.2% male, mean age (±SD) 16.9 ± 5.7 months] were enrolled. The SPT and the DBPCFC with the new AAF were negative in all study subjects. Conclusions The study results support the hypoallergenicity of the new AAF. This formula could be considered an additional dietary option for non-breastfed children affected by CMA. Trial registration The trial was registered in the ClinicalTrials.gov Protocol Registration System (ID number: NCT03909113).


1993 ◽  
Vol 152 (9) ◽  
pp. 760-762 ◽  
Author(s):  
V. Ragno ◽  
P. G. Giampietro ◽  
G. Bruno ◽  
L. Businco

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