scholarly journals Comparison of Disease-Modifying Therapies for the Management of Multiple Sclerosis: Analysis of Healthcare Resource Utilization and Relapse Rates from US Insurance Claims Data

2017 ◽  
Vol 2 (1) ◽  
pp. 31-41 ◽  
Author(s):  
Jacqueline Nicholas ◽  
Aaron Boster ◽  
Ning Wu ◽  
Wei-Shi Yeh ◽  
Monica Fay ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Resource Utilization ◽  
Claims Data ◽  
Healthcare Resource ◽  
Healthcare Resource Utilization ◽  
Insurance Claims ◽  
Disease Modifying Therapies ◽  
Insurance Claims Data ◽  
Disease Modifying ◽  
Relapse Rates

scholarly journals Clinical efficacy of teriflunomide over a fixed 2-year duration in the TOWER study

2018 ◽  
Vol 4 (2) ◽  
pp. 205521731877523 ◽  
Author(s):  
Mark S Freedman ◽  
Julia Morawski ◽  
Karthinathan Thangavelu
Keyword(s):  
Multiple Sclerosis ◽  
Clinical Outcomes ◽  
Clinical Efficacy ◽  
Phase 3 ◽  
Comparative Analyses ◽  
Disease Modifying Therapies ◽  
Disease Modifying ◽  
Intent To Treat ◽  
Relapse Rates

Patients enrolled in the phase 3 TOWER study (NCT00751881) of teriflunomide had variable treatment durations (48–173 weeks). This has led to challenges when interpreting results in the context of other phase 3 trials of disease-modifying therapies for multiple sclerosis, which typically have a fixed 2-year duration. This communication reports clinical outcomes in TOWER over a fixed 2-year period. Reductions in annualised relapse rates and 12-week confirmed disability worsening associated with teriflunomide were comparable between overall intent-to-treat and fixed 2-year study populations in TOWER. Consistency in outcomes supports the inclusion of TOWER data in comparative analyses with other disease-modifying therapies. ClinicalTrials.gov: NCT00751881.

scholarly journals Mo1996 – Assessing Severity and Healthcare Resource Utilization in Celiac Disease: A U.S. Claims Data Analysis

2019 ◽  
Vol 156 (6) ◽  
pp. S-916-S-917
Author(s):  
Aliki Taylor ◽  
Barbara H. Johnson ◽  
Katherine Cappell ◽  
Steve Gelwicks ◽  
Song Wang ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Data Analysis ◽  
Resource Utilization ◽  
Claims Data ◽  
Healthcare Resource ◽  
Healthcare Resource Utilization ◽  
Claims Data Analysis
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