Understanding the diversification pattern of three subspecies of swamp deer (Rucervus duvaucelii) during the Pleistocene–Holocene based on mitochondrial and Y chromosome markers

2021 ◽  
Vol 101 (2) ◽  
pp. 217-232
Author(s):  
Ved Prakash Kumar ◽  
Bheem Dutt Joshi ◽  
Reeta Sharma ◽  
Ankita Rajpoot ◽  
Animesh Talukdar ◽  
...  
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Rossana Santiago de Sousa Azulay ◽  
Luís Cristóvão Porto ◽  
Dayse Aparecida Silva ◽  
Maria da Glória Tavares ◽  
Roberta Maria Duailibe Ferreira Reis ◽  
...  

AbstractThis study aimed to investigate the relationship between genetic ancestry inferred from autosomal and Y chromosome markers and HLA genotypes in patients with Type 1 Diabetes from an admixed Brazilian population. Inference of autosomal ancestry; HLA-DRB1, -DQA1 and -DQB1 typifications; and Y chromosome analysis were performed. European autosomal ancestry was about 50%, followed by approximately 25% of African and Native American. The European Y chromosome was predominant. The HLA-DRB1*03 and DRB1*04 alleles presented risk association with T1D. When the Y chromosome was European, DRB1*03 and DRB1*04 homozygote and DRB1*03/DRB1*04 heterozygote genotypes were the most frequent. The results suggest that individuals from Maranhão have a European origin as their major component; and are patrilineal with greater frequency from the R1b haplogroup. The predominance of the HLA-DRB1*03 and DRB1*04 alleles conferring greater risk in our population and being more frequently related to the ancestry of the European Y chromosome suggests that in our population, the risk of T1D can be transmitted by European ancestors of our process miscegenation. However, the Y sample sizes of Africans and Native Americans were small, and further research should be conducted with large mixed sample sizes to clarify this possible association.


2020 ◽  
Vol 56 (7) ◽  
pp. 849-855
Author(s):  
V. N. Kharkov ◽  
L. M. Novikova ◽  
O. V. Shtygasheva ◽  
F. A. Luzina ◽  
I. Yu. Khitrinskaya ◽  
...  

Author(s):  
Tatiana Karafet ◽  
Stephen L. Zegura ◽  
Jennifer Vuturo-Brady ◽  
Olga Posukh ◽  
Ludmila Osipova ◽  
...  

Author(s):  
Y. V. Bogunov ◽  
◽  
O. V. Maltseva ◽  
A. A. Bogunova ◽  
E. V. Balanovskaya ◽  
...  

2014 ◽  
Vol 50 (2) ◽  
pp. 180-190 ◽  
Author(s):  
V. N. Kharkov ◽  
K. V. Khamina ◽  
O. F. Medvedeva ◽  
K. V. Simonova ◽  
E. R. Eremina ◽  
...  

2015 ◽  
Vol 14 ◽  
pp. 210-218 ◽  
Author(s):  
Jorge Mario Cárdenas ◽  
Tanja Heinz ◽  
Jacobo Pardo-Seco ◽  
Vanesa Álvarez-Iglesias ◽  
Patricia Taboada-Echalar ◽  
...  

2013 ◽  
Vol 7 (3) ◽  
pp. e66-e68 ◽  
Author(s):  
Michael D. Coble ◽  
Carolyn R. Hill ◽  
John M. Butler

2021 ◽  
Author(s):  
Rossana Santiago de Sousa Azulay ◽  
Luís Cristóvão Porto ◽  
Dayse Aparecida Silva ◽  
Maria da Gloria Tavares ◽  
Roberta Dualibe ◽  
...  

Abstract This study aimed to investigate the relationship between genetic ancestry inferred from autosomal and Y chromosome markers and HLA genotypes in patients with Type 1 Diabetes from an admixed Brazilian population. Inference of autosomal ancestry; HLA-DRB1, -DQA1 and -DQB1 typifications; and Y chromosome analysis were performed. European autosomal ancestry was about 50%, followed by approximately 25% of African and Native American. The European Y chromosome was predominant. The HLA-DRB1* 03 and DRB1* 04 alleles presented risk association with T1D. When the Y chromosome was European, DRB1*03 and DRB1*04 homozygote and DRB1*03/DRB1*04 heterozygote genotypes were the most frequent. The results suggest that individuals from Maranhão have a European origin as their major component; and are patrilineal with greater frequency from the R1b haplogroup. The predominance of the HLA-DRB1* 03 and DRB1* 04 alleles conferring greater risk in our population and being more frequently related to the ancestry of the European Y chromosome suggests that in our population, the risk of T1D can be transmitted by European ancestors of our process miscegenation. However, the Y sample sizes of Africans and Native Americans were small, and further research should be conducted with large mixed sample sizes to clarify this possible association.


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